| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2KSN1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000135421 |
| Ensembl nucleotide ID | ENSDARG00000035120 |
| Gene name | Glycine dehydrogenase (aminomethyl-transferring) |
| Gene symbol | gldc |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQSCAKSWRV VISRSVSARV PYSNISRKGD VFNKLKATTG DVSANVRCLA TSQVLWSRKI 60 ERILPRHDEF SERHIGPGDK EKREMLNTLG VESVSQLIEN TIPPSIRLGR SLKMDDPVCE 120 NEILDSLQKI ASKNKMWRSY IGMGYYNCSV PPVIQRNLLE NSGWVTQYTP YQPEVSQGRL 180 ESLLNYQTMV CDITGMAVAN ASLLDEGTAA AEAMQLCNRQ NKRRMFYIDP RCHPQTIAVV 240 QTRANYLSIY LSIYLSIYLS ISVFSVCFFL SFCFFLSVHL SVCFSVCLSL FVSISLCFSV 300 CLSLLFFLPV LSFSICLSIF VSQSLSLSLS LTAKFIYFII LKTNLVVLNG QMCPVRDAAG 360 KEVYRLALQT REQHIRRDKA TSNICTAQAL LANMAAMYAL YHGSQGLRHI AERTHNATLI 420 LAEGLKRAGH KLQHENFFDT LKINCGVAGK DILEKATQRE INLRVYSDGL VRNLLYEPYN 480 VKMFTFSVWI FVCSLFIFLS IFQKLIKTTS ENLLICLKHF RKFISYLLFN IYIYIYIYIY 540 MYIYIYIKNN STFYHFNLLL GSCTMKLNSS SELMPITWRE FANIHPFVPL DQAEGYQLLF 600 RQLEKDLCEI TGYDKISFQP NSGAQGEYAG LAAIKAYLNS RGESHRTVDK HKANLAAIMI 660 TYPSTNGVFE ENVSEVCELI HENGGQVYLD GANMNAQVGL CRPGDYGSDV SHLNLHKTFC 720 IPHGGGGPGM GPIGVKQHLA PFLPSHPVVN MQSNNAGSSL GTISAAPWGS SAILPISWAY 780 IKMMGSKGLA HATEVAILNA NYMAKRLENQ YKILFRGTKG FVAHEFILDV RPFKKTANIE 840 AVDVAKRLQD YGFHAPTMSW PVAGTLMIEP TESEDKAELD RFCDSLLAIR QEIADIEEGR 900 MDSRVNPLKM APHSLACITS STWDRPYPRE FAAFPMPFVR PETKFWPTIS RIDDIYGDQH 960 LVCTCPPMDV YESPYEERAS S 981 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLDC | 507688 | E1BJQ1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 481534 | A0A5F4C8B1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 102174205 | A0A452FM63 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 2731 | P23378 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gldc | 104174 | Q91W43 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GLDC | A0A2I3RPM1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480TLS3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | GLDC | 100343694 | G1SL36 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gldc | A0A0G2JUZ5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | gldc | A0A0G2KSN1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005960 | glycine cleavage complex |
| GO:0016021 | integral component of membrane |
| GO:0005739 | mitochondrion |
| GO:0016594 | glycine binding |
| GO:0004375 | glycine dehydrogenase (decarboxylating) activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019464 | glycine decarboxylation via glycine cleavage system |
| Pfam ID | Pfam Term |
|---|---|
| PF02347 | GDC-P |