| Tag | Content |
|---|---|
| Uniprot ID | A0A480TLS3 |
| Entrez ID | |
| Genbank protein ID | HDC26367.1; HDB60254.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Glycine cleavage system P protein |
| Gene symbol | |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | The glycine cleavage system catalyzes the degradation of glycine. |
| Sequence | MQTCARAWGL RLGCGVGGSR RLAGGAGLRW APSGRDSSSG GGDGGGDSRG AAASRLLERL 60 LPRHDDFARR HIGPGDKDQR EMLQALGLAS VDELIEKTVP ASIRLKRPLK MDDPICENEI 120 LATLHAISSK NQIWRSYIGM GYYNCSVPQT ILRNLLENSG WITQYTPYQP EVSQGRLESL 180 LNYQTMVCDI TGMDTANASL LDEGTAAAEA MQLCHRHNKR RKFFVDPRCH PQTIAVIQTR 240 AKYAGVLIEL KLPHEMDFSG KDVSGVLFQY PDTEGKVEDF TELVERAHQA GSLACCATDL 300 LALCILKPPG EFGVDIALGS SQRFGVPLGY GGPHAAFFAV RESLVRMMPG RMVGVTRDAS 360 GKEVYRLALQ TREQHIRRDK ATSNICTAQA LLANMAAMFA IYHGSHGLEH IARRVHNATL 420 ILSEGLKRAG HQLQHNLFFD TLKIHCGCSV KEVLGRAAQR QINIRLFEDD TLGISLDETV 480 NEKDLDDLLW IFGCESSAEL VAESMGEEQR GILGTAFKRT SPFLTHQVFN SYHSETNIVR 540 YMKKLENKDI SLVHSMIPLG SCTMKLNSSS ELTPITWKEF ANIHPFVPLD QAQGYQQLFQ 600 ELEKDLCELT GYDRISFQPN SGAQGEYAGL ATIRAYLDQK GERHRVVCLI PKSAHGTNPA 660 SAHMAGMKIQ PIEVDKYGNI DVAHLKAMVD KHKENLAAIM ITYPSTNGVF EENIGDVCDL 720 IHQHGGQVYL DGANMNAQVG ICRPGDFGSD VSHLNLHKTF CIPHGGGGPG MGPIGVKKHL 780 VPFLPNHPII SVKPSEDAQP LGTVSAAPWG SSSILPISWA YIKMMGGKGL KQATEIAILN 840 ANYMAKRLEK HYRVLFRGAR GYVAHEFILD TRPFKKSANI EAVDVAKRLQ DYGFHAPTMS 900 WPVAGTLMIE PTESEDKAEL DRFCDAMISI RQEISDIEEG RIDPRVNPLK MSPHSLTCVT 960 SSHWDRPYSR EVAAFPLPFV KPENKFWPTI ARIDDIYGDQ HLVCTCPPMD VYESPFSEQK 1020 RASS 1024 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLDC | 507688 | E1BJQ1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 481534 | A0A5F4C8B1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 102174205 | A0A452FM63 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 2731 | P23378 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gldc | 104174 | Q91W43 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GLDC | A0A2I3RPM1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480TLS3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | GLDC | 100343694 | G1SL36 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gldc | A0A0G2JUZ5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | gldc | A0A0G2KSN1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0004375 | glycine dehydrogenase (decarboxylating) activity |
| GO:0016829 | lyase activity |
| GO:0006546 | glycine catabolic process |