| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3RPM1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000066639 |
| Ensembl nucleotide ID | ENSPTRG00000029347 |
| Gene name | Glycine cleavage system P protein |
| Gene symbol | GLDC |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | The glycine cleavage system catalyzes the degradation of glycine. |
| Sequence | SSLPVCENEI LATLHAISSK NQIWRSYIGM GYYNCSVPQT ILRNLLENSG WITQYTPYQP 60 EVSQGRLESL LNYQTMVCDI TGLDMANASL LDEGTAAAEA LQLCYRHNKR RKFFVDPRCH 120 PQTIAVVQTR AKYTGVLTEL KLPCEMDFSG KDVSGVLFQY PDTEGKVEDF TELVERAHQS 180 GSLACCATDL LALCILRPPG EFGVDIALGS SQRFGVPLGY GGPHAAFFAV RESLVRMMPG 240 RMVGVTRDAT GKEVYRLTLQ TREQHIRRDK ATSNICTAQA LLANMAAMFA IYHGSHGLEH 300 IARRVHNATL ILSEGLKRAG HQLQHDLFFD TLKIQCGCSV KEVLGRAAQR QINFRLFEDG 360 TLGISLDETV NEKDLDDLLW IFGCESSAEL VAESMGEECR GIPGSVFKRT SPFLTHQVFN 420 SYHSETNIVR YMKKLENKDI SLVHSMIPLG SCTMKLNSSS ELAPITWKEF ANIHPFVPLD 480 QAQGYQQLFR ELEKDLCELT GYDQVCFQPN SGAQGEYAGL ATIRAYLNQK GEGHRTVCLI 540 PKSAHGTNPA SAHMAGMKIQ PVEVDKYGNI DAVHLKAMVD KHKENLAAIM ITYPSTNGVF 600 EENISDVCDL IHQHGGQVYL DGANMNAQVG ICRPGDFGSD VSHLNLHKTF CIPHGGGGPG 660 MGPIGVKKHL APFLPNHPVI SLKRNEDACP VGTVSAAPWG SSSILPISWA YIKMMGGKGL 720 KQATETAILN ANYMAKRLEK HYRILFRGAR GYVGHEFILD TRPFKKSANI EAVDVAKRLQ 780 DYGFHAPTMS WPVAGTLMVE PTESEDKAEL DRFCDAMISI RQEIADIEEG RVDPRVNPLK 840 MSPHSLTCVT SSHWDRPYSR EVAAFPLPFV KPENKFWPTI ARIDDIYGDQ HLVCTCPPME 900 VYESPFSEQK RASS 914 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLDC | 507688 | E1BJQ1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 481534 | A0A5F4C8B1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 102174205 | A0A452FM63 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 2731 | P23378 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gldc | 104174 | Q91W43 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GLDC | A0A2I3RPM1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480TLS3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | GLDC | 100343694 | G1SL36 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gldc | A0A0G2JUZ5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | gldc | A0A0G2KSN1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0004375 | glycine dehydrogenase (decarboxylating) activity |
| GO:0016829 | lyase activity |
| GO:0006546 | glycine catabolic process |