| Tag | Content |
|---|---|
| Uniprot ID | G1SL36 |
| Entrez ID | 100343694 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002708098.3 |
| Ensembl protein ID | ENSOCUP00000003560 |
| Ensembl nucleotide ID | ENSOCUG00000004106 |
| Gene name | Glycine cleavage system P protein |
| Gene symbol | GLDC |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | The glycine cleavage system catalyzes the degradation of glycine. |
| Sequence | MQSCARTWRL RLGSGVGGGR RLPAGARPHL VPRVRDSSSG GGDSGAAGAS RLLERLLPRH 60 DDFAERHIGP GDKDQREMLQ ALGLASIDEL IEKTVPASIR LKRPLKMEDP ICENEILSTL 120 RAISRKNLIW RSYIGMGYYN CSVPQAILRN LLENSGWITQ YTPYQPEISQ GRLESLLNYQ 180 TMVCDMTGMD TANASLLDEA TAAAEAMQLC YRHNKRKKFF VDPRCHPQTI AVIQTRAKYN 240 GVLIELKLPH EMDFSGKDVS GVLFQYPDTE GKVEDFTELV ERAHQTGSLT CCATDLLALC 300 ILRPPGEFGV DIALGSSQRF GVPLGYGGPH AAFFAVRENL VRMMPGRMVG VTRDATGKEV 360 YRLALQTREQ HIRRDKATSN ICTAQALLAN MAAMFAIYHG SRGLEHIARR VHNATLILSE 420 GLKRAGHALQ HDLFFDTLKV QCGCSVKEVL GRAAQRQINF RIFEDGTLGI SLDETVNEKD 480 LDDLLWIFGC ESSAELLAEC MGEELRGIPG SAFKRTSPYL THQVFNRYHS ETNIVRYMKK 540 LENKDISLVH SMIPLGSCTM KLNSSSELSP ITWKEFANIH PFVPLDQAQG YQQLFRELEK 600 DLCELTGYDQ ISFQPNSGAQ GEYAGLATIR AYLDWKGERH RTVCLIPKSA HGTNPASAHM 660 AGMKIQPVEV DKYGNIDAAH LKAMVDKHKE NLAAIMITYP STNGVFEENI SDVCALIHQH 720 GGQVYLDGAN MNAQVGICRP GDFGSDVSHL NLHKTFCIPH GGGGPGMGPI GVKKHLAPFL 780 PNHPIISVKP NEDTWPVGTV SAAPWGSSSI LPISWAYIKM MGGKGLKQAT EIAILNANYM 840 AKRLEKHYRV LFRGARGFVA HEFILDTRPF KKSANIEAVD VAKRLQDYGF HAPTMSWPVA 900 GTLMVEPTES EDKAELDRFC DAMISIRQEI ADIEDGRVDP KVNPLKMSPH SLTCVTSSHW 960 DRPYSREVAA FPLPFVKPEN KFWPTIARID DIYGDQHLVC TCPPMEVYES PFSEQKRASS 1020 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLDC | 507688 | E1BJQ1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 481534 | A0A5F4C8B1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 102174205 | A0A452FM63 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLDC | 2731 | P23378 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gldc | 104174 | Q91W43 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GLDC | A0A2I3RPM1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480TLS3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | GLDC | 100343694 | G1SL36 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gldc | A0A0G2JUZ5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | gldc | A0A0G2KSN1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0005654 | nucleoplasm |
| GO:0005886 | plasma membrane |
| GO:0004375 | glycine dehydrogenase (decarboxylating) activity |
| GO:0016829 | lyase activity |
| GO:0006546 | glycine catabolic process |