Gene Page: IFI44

Summary ?
GeneID10561
SymbolIFI44
SynonymsMTAP44|TLDC5|p44
Descriptioninterferon induced protein 44
ReferenceMIM:610468|HGNC:HGNC:16938|Ensembl:ENSG00000137965|HPRD:09998|Vega:OTTHUMG00000009723
Gene typeprotein-coding
Map location1p31.1
Pascal p-value0.016
Sherlock p-value0.936
eGeneCerebellar Hemisphere
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IIAGenome scan meta-analysis (All samples)Psr: 0.02692 

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2046622chr179610142IFI44105610.04cis
rs17092900chr173003409IFI44105613.605E-6trans
rs1338574chr1100083461IFI44105610.11trans
rs17121311chr1100314968IFI44105610.14trans
rs12091025chr1149989802IFI44105610.18trans
rs11205098chr1152717431IFI44105610trans
rs16857588chr211675145IFI44105610.03trans
rs10495652chr217139288IFI44105610.01trans
rs6531271chr217139932IFI44105610.01trans
rs12620194chr217148003IFI44105610.01trans
rs1900263chr280376061IFI44105610.01trans
rs10496239chr280376968IFI44105610.01trans
rs11679783chr280377391IFI44105610.01trans
rs17018721chr280385148IFI44105610.02trans
rs2862022chr280388509IFI44105610.01trans
rs17043176chr2114025371IFI44105610trans
rs11897086chr2184596267IFI44105610.17trans
rs10187085chr2184614775IFI44105610.14trans
rs9989867chr2184628012IFI44105610.14trans
rs890527chr3140774852IFI44105610.1trans
rs7612673chr3154499328IFI44105610.02trans
rs159171chr521186325IFI44105610.03trans
rs1678893chr531763244IFI44105619.982E-8trans
snp_a-22745050IFI44105610.01trans
rs4705861chr5131800763IFI44105610.16trans
rs10491308chr5140678473IFI44105610.01trans
rs10516136chr5176381368IFI44105610.04trans
rs13176869chr5179203478IFI44105615.139E-4trans
rs13362722chr66171044IFI44105610.01trans
rs9396602chr615766500IFI44105610.15trans
rs17668963chr684811128IFI44105610.03trans
rs1080960chr684815420IFI44105619.205E-4trans
rs133627530IFI44105610trans
rs7741955chr684829621IFI44105613.94E-4trans
rs17186320chr684897846IFI44105610.18trans
rs17186572chr684903663IFI44105610.11trans
rs6454356chr684917509IFI44105610.12trans
rs12524136chr684935440IFI44105610trans
rs16883826chr691671158IFI44105610.14trans
rs1918752chr6144909076IFI44105610.1trans
rs9376870chr6145206590IFI44105610.18trans
rs7765650chr6145384057IFI44105610.2trans
rs9397692chr6154487314IFI44105615.144E-5trans
rs10485060chr6154516100IFI44105613.24E-4trans
rs9384190chr6154524473IFI44105613.324E-4trans
rs17292544chr6154544809IFI44105611.882E-5trans
rs4591922chr721612318IFI44105610.15trans
rs17171716chr740505332IFI44105612.706E-4trans
rs17160749chr777689922IFI44105610.01trans
rs3779321chr777691378IFI44105610.01trans
rs11974883chr778068523IFI44105610.03trans
rs6943724chr786977647IFI44105610.19trans
rs10503326chr85533604IFI44105610.17trans
rs6586742chr818208340IFI44105610.13trans
rs6994367chr858489813IFI44105610.09trans
rs16922399chr858514611IFI44105610.09trans
rs6994006chr858584893IFI44105610.09trans
rs1550464chr873674315IFI44105610.06trans
rs6986838chr891194553IFI44105610.16trans
rs10283729chr92981636IFI44105610.12trans
rs201062chr1010985931IFI44105610.01trans
rs17111364chr1097901813IFI44105610.16trans
rs10833144chr1119656451IFI44105614.662E-4trans
rs11039838chr1148592091IFI44105610.15trans
rs2367635chr11116129753IFI44105610.16trans
rs2508654chr11120405519IFI44105610.15trans
rs11067420chr12115559121IFI44105610.13trans
rs17061055chr1340835399IFI44105615.976E-4trans
rs17066364chr1345515988IFI44105614.404E-5trans
rs3783149chr1345582764IFI44105610.04trans
rs7332969chr1345612902IFI44105614.404E-5trans
rs4943038chr1352482674IFI44105610.18trans
rs10484008chr1489376562IFI44105612.441E-4trans
rs10150770chr1495375311IFI44105610.01trans
rs16955413chr1529677652IFI44105614.012E-7trans
rs4457950chr1535445709IFI44105610.02trans
rs16969948chr1578864785IFI44105610.13trans
rs16955238chr1681415690IFI44105610.05trans
rs16955255chr1681420130IFI44105610trans
rs16955259chr1681420188IFI44105610.05trans
rs4303487chr1690033254IFI44105610.16trans
rs8098388chr1824080746IFI44105610.01trans
rs8085520chr1840184498IFI44105610.13trans
rs8105452chr1911854016IFI44105610.06trans
rs8104298chr1911867512IFI44105610trans
rs16979927chr2055019249IFI44105616.438E-7trans
rs17433434chr2056487374IFI44105610.11trans
rs17000687chr2249634054IFI44105610.05trans
rs17347454chrX23347700IFI44105614.213E-8trans
rs5952435chrX47321870IFI44105610.07trans
rs689365chrX97074769IFI44105611.599E-4trans
rs108561330IFI44105610trans
rs16995164chrX148536507IFI44105610trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009615response to virusTAS7925411 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL UP 6938All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL DN 7442All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463290All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL UP 276187All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL DN 455304All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS UP 306188All SZGR 2.0 genes in this pathway
NOJIMA SFRP2 TARGETS DN 2518All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN 275168All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP 182110All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP 15791All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP 194122All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP 175108All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 DN 242165All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 DN 281186All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE UP 204140All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP 157104All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431237All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375806All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE DN 485334All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP 552347All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP 211136All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS F UP 185119All SZGR 2.0 genes in this pathway
OUELLET OVARIAN CANCER INVASIVE VS LMP UP 11785All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER CLUSTER 1 4423All SZGR 2.0 genes in this pathway
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM UP 8157All SZGR 2.0 genes in this pathway
EINAV INTERFERON SIGNATURE IN CANCER 2716All SZGR 2.0 genes in this pathway
DAUER STAT3 TARGETS DN 5034All SZGR 2.0 genes in this pathway
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP 7347All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442892All SZGR 2.0 genes in this pathway
GROSS ELK3 TARGETS DN 3217All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP 769437All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037673All SZGR 2.0 genes in this pathway
DER IFN ALPHA RESPONSE UP 7448All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398262All SZGR 2.0 genes in this pathway
BECKER TAMOXIFEN RESISTANCE UP 5036All SZGR 2.0 genes in this pathway
RADAEVA RESPONSE TO IFNA1 UP 5240All SZGR 2.0 genes in this pathway
DER IFN BETA RESPONSE UP 10267All SZGR 2.0 genes in this pathway
GRANDVAUX IRF3 TARGETS UP 1512All SZGR 2.0 genes in this pathway
LEE LIVER CANCER MYC E2F1 UP 5634All SZGR 2.0 genes in this pathway
LEE LIVER CANCER E2F1 UP 6235All SZGR 2.0 genes in this pathway
ROETH TERT TARGETS UP 1411All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED DN 246180All SZGR 2.0 genes in this pathway
LIANG SILENCED BY METHYLATION 2 5334All SZGR 2.0 genes in this pathway
TRAYNOR RETT SYNDROM UP 4533All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 16HR UP 225139All SZGR 2.0 genes in this pathway
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP 314201All SZGR 2.0 genes in this pathway
CHANG IMMORTALIZED BY HPV31 DN 6545All SZGR 2.0 genes in this pathway
BROWNE INTERFERON RESPONSIVE GENES 6844All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL 254164All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 12HR UP 11168All SZGR 2.0 genes in this pathway
BAELDE DIABETIC NEPHROPATHY DN 434302All SZGR 2.0 genes in this pathway
KIM LRRC3B TARGETS 3024All SZGR 2.0 genes in this pathway
HOWLIN CITED1 TARGETS 2 UP 1710All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P6 9144All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE UP 15692All SZGR 2.0 genes in this pathway
HELLER SILENCED BY METHYLATION UP 282183All SZGR 2.0 genes in this pathway
WALLACE PROSTATE CANCER RACE UP 299167All SZGR 2.0 genes in this pathway
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN 154101All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430288All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973570All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940425All SZGR 2.0 genes in this pathway
MOSERLE IFNA RESPONSE 3119All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP 425298All SZGR 2.0 genes in this pathway
ZHANG INTERFERON RESPONSE 2314All SZGR 2.0 genes in this pathway
WUNDER INFLAMMATORY RESPONSE AND CHOLESTEROL UP 5838All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2 356214All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE UP 181106All SZGR 2.0 genes in this pathway
BOYAULT LIVER CANCER SUBCLASS G5 DN 2717All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721492All SZGR 2.0 genes in this pathway
OHGUCHI LIVER HNF4A TARGETS UP 4430All SZGR 2.0 genes in this pathway
KIM PTEN TARGETS UP 189All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS UP 169105All SZGR 2.0 genes in this pathway
PLASARI TGFB1 SIGNALING VIA NFIC 1HR DN 10677All SZGR 2.0 genes in this pathway
PLASARI TGFB1 SIGNALING VIA NFIC 10HR UP 5438All SZGR 2.0 genes in this pathway
KRIEG KDM3A TARGETS NOT HYPOXIA 208107All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784464All SZGR 2.0 genes in this pathway
BOSCO INTERFERON INDUCED ANTIVIRAL MODULE 7848All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP 289184All SZGR 2.0 genes in this pathway
ZWANG DOWN BY 2ND EGF PULSE 293119All SZGR 2.0 genes in this pathway
HECKER IFNB1 TARGETS 9554All SZGR 2.0 genes in this pathway