Gene Page: GNAI1
Summary ?
GeneID | 2770 |
Symbol | GNAI1 |
Synonyms | Gi |
Description | G protein subunit alpha i1 |
Reference | MIM:139310|HGNC:HGNC:4384|Ensembl:ENSG00000127955|HPRD:00756|Vega:OTTHUMG00000023523 |
Gene type | protein-coding |
Map location | 7q21 |
Pascal p-value | 0.003 |
Sherlock p-value | 0.005 |
Fetal beta | 0.448 |
eGene | Caudate basal ganglia Cerebellar Hemisphere Myers' cis & trans |
Support | CANABINOID G-PROTEIN RELAY SEROTONIN Potential synaptic genes |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 1.2615 |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs6040607 | chr20 | 11371092 | GNAI1 | 2770 | 0.14 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
TP53I13 | 0.76 | 0.76 |
RFXANK | 0.74 | 0.69 |
CAPG | 0.74 | 0.67 |
AKR7A2 | 0.72 | 0.66 |
TMEM149 | 0.72 | 0.68 |
TIMP1 | 0.70 | 0.72 |
CLIC1 | 0.69 | 0.63 |
TMEM179B | 0.69 | 0.67 |
TMEM216 | 0.69 | 0.50 |
AL031319.2 | 0.69 | 0.56 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
FBXW7 | -0.50 | -0.61 |
AL031003.1 | -0.47 | -0.56 |
RAB11FIP4 | -0.47 | -0.57 |
TRIM44 | -0.46 | -0.54 |
ERC2 | -0.45 | -0.58 |
SCN2A | -0.45 | -0.59 |
KIF3A | -0.45 | -0.57 |
STXBP5 | -0.44 | -0.56 |
DNAJC6 | -0.44 | -0.56 |
MADD | -0.44 | -0.56 |
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0000166 | nucleotide binding | IEA | - | |
GO:0004871 | signal transducer activity | IEA | - | |
GO:0003924 | GTPase activity | TAS | 2834384 | |
GO:0005515 | protein binding | IPI | 15537540 | |
GO:0005525 | GTP binding | IEA | - | |
GO:0019001 | guanyl nucleotide binding | IEA | - | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0007186 | G-protein coupled receptor protein signaling pathway | IEA | - | |
GO:0007165 | signal transduction | IEA | - | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0005834 | heterotrimeric G-protein complex | TAS | 3110783 | |
GO:0005886 | plasma membrane | TAS | 3139448 |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
ADCY5 | AC5 | adenylate cyclase 5 | - | HPRD,BioGRID | 9748257 |
ADRA2A | ADRA2 | ADRA2R | ADRAR | ALPHA2AAR | ZNF32 | adrenergic, alpha-2A-, receptor | - | HPRD | 11732925 |
CD47 | IAP | MER6 | OA3 | CD47 molecule | - | HPRD | 11306274 |
CNR1 | CANN6 | CB-R | CB1 | CB1A | CB1K5 | CB1R | CNR | cannabinoid receptor 1 (brain) | - | HPRD,BioGRID | 11168387 |
CRHR1 | CRF-R | CRF1 | CRFR1 | CRH-R1h | CRHR | CRHR1f | corticotropin releasing hormone receptor 1 | - | HPRD,BioGRID | 10598591 |
DRD3 | D3DR | ETM1 | FET1 | MGC149204 | MGC149205 | dopamine receptor D3 | - | HPRD | 10978845 |
EPOR | MGC138358 | erythropoietin receptor | Reconstituted Complex | BioGRID | 12538595 |
FFAR1 | FFA1R | GPCR40 | GPR40 | free fatty acid receptor 1 | - | HPRD,BioGRID | 12496284 |12629551 |
GPR1 | - | G protein-coupled receptor 1 | - | HPRD | 14530282 |
GPR143 | OA1 | G protein-coupled receptor 143 | - | HPRD,BioGRID | 10471510 |
GPSM1 | AGS3 | DKFZp727I051 | G-protein signaling modulator 1 (AGS3-like, C. elegans) | Reconstituted Complex | BioGRID | 14530282 |
GPSM2 | LGN | Pins | G-protein signaling modulator 2 (AGS3-like, C. elegans) | LGN interacts with Galphai1. | BIND | 15537540 |
GPSM3 | C6orf9 | G18 | G18.1a | G18.1b | G18.2 | NG1 | G-protein signaling modulator 3 (AGS3-like, C. elegans) | - | HPRD,BioGRID | 14656218 |
HRH4 | AXOR35 | BG26 | GPCR105 | GPRv53 | H4 | H4R | HH4R | MGC133027 | histamine receptor H4 | - | HPRD | 10973974 |
HTR2A | 5-HT2A | HTR2 | 5-hydroxytryptamine (serotonin) receptor 2A | - | HPRD | 11916537 |
IGF1R | CD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216 | insulin-like growth factor 1 receptor | - | HPRD,BioGRID | 10644671 |
NGB | - | neuroglobin | Reconstituted Complex | BioGRID | 12860983 |
NUMA1 | NUMA | nuclear mitotic apparatus protein 1 | NuMA interacts with Galphai1. | BIND | 15537540 |
OPRM1 | KIAA0403 | MOR | MOR1 | OPRM | opioid receptor, mu 1 | - | HPRD,BioGRID | 12068084 |
RASD1 | AGS1 | DEXRAS1 | MGC:26290 | RAS, dexamethasone-induced 1 | in vitro Reconstituted Complex | BioGRID | 10840027 |11842095 |
RGS10 | - | regulator of G-protein signaling 10 | - | HPRD,BioGRID | 9207071 |
RGS12 | DKFZp761K1617 | DKFZp761K1817 | regulator of G-protein signaling 12 | - | HPRD,BioGRID | 11387333 |
RGS14 | - | regulator of G-protein signaling 14 | - | HPRD,BioGRID | 11387333 |11976690 |
RGS16 | A28-RGS14 | A28-RGS14P | RGS-R | regulator of G-protein signaling 16 | Biochemical Activity | BioGRID | 10878019 |
RGS18 | RGS13 | regulator of G-protein signaling 18 | - | HPRD,BioGRID | 11955952 |
RGS19 | GAIP | RGSGAIP | regulator of G-protein signaling 19 | - | HPRD,BioGRID | 8986788 |10364213 |
RGS4 | DKFZp761F1924 | MGC2124 | MGC60244 | RGP4 | SCZD9 | regulator of G-protein signaling 4 | - | HPRD,BioGRID | 9660808 |11507164 |
RGS5 | MST092 | MST106 | MST129 | MSTP032 | MSTP092 | MSTP106 | MSTP129 | regulator of G-protein signaling 5 | Affinity Capture-Western | BioGRID | 11253162 |
RGS7 | - | regulator of G-protein signaling 7 | - | HPRD,BioGRID | 9572280 |
RIC8A | MGC104517 | MGC131931 | MGC148073 | MGC148074 | RIC8 | synembryn | resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | - | HPRD,BioGRID | 12509430 |
S1PR1 | CHEDG1 | D1S3362 | ECGF1 | EDG-1 | EDG1 | FLJ58121 | S1P1 | sphingosine-1-phosphate receptor 1 | - | HPRD,BioGRID | 8626678 |
S1PR2 | AGR16 | EDG-5 | EDG5 | Gpcr13 | H218 | LPB2 | S1P2 | sphingosine-1-phosphate receptor 2 | - | HPRD | 10488065 |
S1PR3 | EDG-3 | EDG3 | FLJ37523 | FLJ93220 | LPB3 | MGC71696 | S1P3 | sphingosine-1-phosphate receptor 3 | - | HPRD | 10488065 |
S1PR5 | EDG8 | Edg-8 | S1P5 | SPPR-1 | SPPR-2 | sphingosine-1-phosphate receptor 5 | - | HPRD | 11069896 |
SSTR2 | - | somatostatin receptor 2 | - | HPRD,BioGRID | 7914078 |
SSTR3 | - | somatostatin receptor 3 | - | HPRD,BioGRID | 8183236 |
STRN | MGC125642 | SG2NA | striatin, calmodulin binding protein | - | HPRD | 15569929 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG CHEMOKINE SIGNALING PATHWAY | 190 | 128 | All SZGR 2.0 genes in this pathway |
KEGG AXON GUIDANCE | 129 | 103 | All SZGR 2.0 genes in this pathway |
KEGG TIGHT JUNCTION | 134 | 86 | All SZGR 2.0 genes in this pathway |
KEGG GAP JUNCTION | 90 | 68 | All SZGR 2.0 genes in this pathway |
KEGG LEUKOCYTE TRANSENDOTHELIAL MIGRATION | 118 | 78 | All SZGR 2.0 genes in this pathway |
KEGG LONG TERM DEPRESSION | 70 | 53 | All SZGR 2.0 genes in this pathway |
KEGG PROGESTERONE MEDIATED OOCYTE MATURATION | 86 | 59 | All SZGR 2.0 genes in this pathway |
KEGG MELANOGENESIS | 102 | 80 | All SZGR 2.0 genes in this pathway |
BIOCARTA SPPA PATHWAY | 22 | 18 | All SZGR 2.0 genes in this pathway |
BIOCARTA BIOPEPTIDES PATHWAY | 45 | 35 | All SZGR 2.0 genes in this pathway |
BIOCARTA CXCR4 PATHWAY | 24 | 22 | All SZGR 2.0 genes in this pathway |
BIOCARTA MPR PATHWAY | 34 | 28 | All SZGR 2.0 genes in this pathway |
BIOCARTA GSK3 PATHWAY | 27 | 26 | All SZGR 2.0 genes in this pathway |
BIOCARTA EDG1 PATHWAY | 27 | 24 | All SZGR 2.0 genes in this pathway |
BIOCARTA GPCR PATHWAY | 37 | 31 | All SZGR 2.0 genes in this pathway |
BIOCARTA PAR1 PATHWAY | 37 | 28 | All SZGR 2.0 genes in this pathway |
ST ADRENERGIC | 36 | 29 | All SZGR 2.0 genes in this pathway |
ST MYOCYTE AD PATHWAY | 27 | 25 | All SZGR 2.0 genes in this pathway |
PID ENDOTHELIN PATHWAY | 63 | 52 | All SZGR 2.0 genes in this pathway |
PID LYSOPHOSPHOLIPID PATHWAY | 66 | 53 | All SZGR 2.0 genes in this pathway |
PID ER NONGENOMIC PATHWAY | 41 | 35 | All SZGR 2.0 genes in this pathway |
PID S1P S1P3 PATHWAY | 29 | 24 | All SZGR 2.0 genes in this pathway |
PID S1P S1P4 PATHWAY | 14 | 11 | All SZGR 2.0 genes in this pathway |
PID SHP2 PATHWAY | 58 | 46 | All SZGR 2.0 genes in this pathway |
PID S1P S1P1 PATHWAY | 21 | 18 | All SZGR 2.0 genes in this pathway |
PID CXCR4 PATHWAY | 102 | 78 | All SZGR 2.0 genes in this pathway |
PID ERBB1 RECEPTOR PROXIMAL PATHWAY | 35 | 29 | All SZGR 2.0 genes in this pathway |
PID S1P META PATHWAY | 21 | 14 | All SZGR 2.0 genes in this pathway |
PID AR NONGENOMIC PATHWAY | 31 | 27 | All SZGR 2.0 genes in this pathway |
PID HEDGEHOG GLI PATHWAY | 48 | 35 | All SZGR 2.0 genes in this pathway |
PID CXCR3 PATHWAY | 43 | 34 | All SZGR 2.0 genes in this pathway |
PID THROMBIN PAR1 PATHWAY | 43 | 32 | All SZGR 2.0 genes in this pathway |
PID S1P S1P2 PATHWAY | 24 | 19 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 186 | 155 | All SZGR 2.0 genes in this pathway |
REACTOME NEURONAL SYSTEM | 279 | 221 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY GPCR | 920 | 449 | All SZGR 2.0 genes in this pathway |
REACTOME INTEGRATION OF ENERGY METABOLISM | 120 | 84 | All SZGR 2.0 genes in this pathway |
REACTOME OPIOID SIGNALLING | 78 | 56 | All SZGR 2.0 genes in this pathway |
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 13 | 9 | All SZGR 2.0 genes in this pathway |
REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL | 137 | 110 | All SZGR 2.0 genes in this pathway |
REACTOME PLC BETA MEDIATED EVENTS | 43 | 32 | All SZGR 2.0 genes in this pathway |
REACTOME G PROTEIN ACTIVATION | 27 | 15 | All SZGR 2.0 genes in this pathway |
REACTOME REGULATION OF INSULIN SECRETION | 93 | 65 | All SZGR 2.0 genes in this pathway |
REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | 25 | 15 | All SZGR 2.0 genes in this pathway |
REACTOME GPCR DOWNSTREAM SIGNALING | 805 | 368 | All SZGR 2.0 genes in this pathway |
REACTOME G ALPHA I SIGNALLING EVENTS | 195 | 114 | All SZGR 2.0 genes in this pathway |
REACTOME G ALPHA S SIGNALLING EVENTS | 121 | 82 | All SZGR 2.0 genes in this pathway |
REACTOME G ALPHA Z SIGNALLING EVENTS | 44 | 29 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNAL AMPLIFICATION | 31 | 19 | All SZGR 2.0 genes in this pathway |
REACTOME ADP SIGNALLING THROUGH P2RY12 | 21 | 10 | All SZGR 2.0 genes in this pathway |
REACTOME GABA B RECEPTOR ACTIVATION | 38 | 26 | All SZGR 2.0 genes in this pathway |
REACTOME GABA RECEPTOR ACTIVATION | 52 | 40 | All SZGR 2.0 genes in this pathway |
REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 208 | 138 | All SZGR 2.0 genes in this pathway |
ONKEN UVEAL MELANOMA DN | 526 | 357 | All SZGR 2.0 genes in this pathway |
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | 663 | 425 | All SZGR 2.0 genes in this pathway |
CHARAFE BREAST CANCER LUMINAL VS BASAL DN | 455 | 304 | All SZGR 2.0 genes in this pathway |
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL DN | 460 | 312 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR UP | 85 | 54 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP | 194 | 122 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP | 175 | 108 | All SZGR 2.0 genes in this pathway |
AKL HTLV1 INFECTION UP | 27 | 16 | All SZGR 2.0 genes in this pathway |
RHEIN ALL GLUCOCORTICOID THERAPY DN | 362 | 238 | All SZGR 2.0 genes in this pathway |
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION GRANULOCYTE UP | 55 | 34 | All SZGR 2.0 genes in this pathway |
SENESE HDAC3 TARGETS DN | 536 | 332 | All SZGR 2.0 genes in this pathway |
KINSEY TARGETS OF EWSR1 FLII FUSION DN | 329 | 219 | All SZGR 2.0 genes in this pathway |
KIM WT1 TARGETS DN | 459 | 276 | All SZGR 2.0 genes in this pathway |
JAATINEN HEMATOPOIETIC STEM CELL UP | 316 | 190 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | 633 | 376 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN | 537 | 339 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA UP | 16 | 7 | All SZGR 2.0 genes in this pathway |
GOZGIT ESR1 TARGETS UP | 149 | 84 | All SZGR 2.0 genes in this pathway |
ENK UV RESPONSE EPIDERMIS DN | 508 | 354 | All SZGR 2.0 genes in this pathway |
LANDIS BREAST CANCER PROGRESSION DN | 70 | 43 | All SZGR 2.0 genes in this pathway |
DELYS THYROID CANCER DN | 232 | 154 | All SZGR 2.0 genes in this pathway |
LINDGREN BLADDER CANCER CLUSTER 1 UP | 121 | 71 | All SZGR 2.0 genes in this pathway |
LANDIS ERBB2 BREAST PRENEOPLASTIC DN | 55 | 33 | All SZGR 2.0 genes in this pathway |
LANDIS ERBB2 BREAST TUMORS 324 DN | 149 | 93 | All SZGR 2.0 genes in this pathway |
HU ANGIOGENESIS DN | 37 | 25 | All SZGR 2.0 genes in this pathway |
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 4NM DN | 7 | 6 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP | 83 | 51 | All SZGR 2.0 genes in this pathway |
WANG RESPONSE TO BEXAROTENE DN | 29 | 19 | All SZGR 2.0 genes in this pathway |
NUYTTEN NIPP1 TARGETS DN | 848 | 527 | All SZGR 2.0 genes in this pathway |
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | 382 | 224 | All SZGR 2.0 genes in this pathway |
GOTZMANN EPITHELIAL TO MESENCHYMAL TRANSITION DN | 206 | 136 | All SZGR 2.0 genes in this pathway |
BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
BENPORATH SOX2 TARGETS | 734 | 436 | All SZGR 2.0 genes in this pathway |
STARK PREFRONTAL CORTEX 22Q11 DELETION UP | 195 | 138 | All SZGR 2.0 genes in this pathway |
LE EGR2 TARGETS DN | 108 | 84 | All SZGR 2.0 genes in this pathway |
NADLER OBESITY DN | 48 | 34 | All SZGR 2.0 genes in this pathway |
LI WILMS TUMOR VS FETAL KIDNEY 1 UP | 182 | 119 | All SZGR 2.0 genes in this pathway |
VERHAAK AML WITH NPM1 MUTATED DN | 246 | 180 | All SZGR 2.0 genes in this pathway |
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
GENTILE UV RESPONSE CLUSTER D4 | 55 | 37 | All SZGR 2.0 genes in this pathway |
WANG CISPLATIN RESPONSE AND XPC DN | 228 | 146 | All SZGR 2.0 genes in this pathway |
GENTILE UV HIGH DOSE DN | 312 | 203 | All SZGR 2.0 genes in this pathway |
SESTO RESPONSE TO UV C0 | 107 | 72 | All SZGR 2.0 genes in this pathway |
WELCSH BRCA1 TARGETS UP | 198 | 132 | All SZGR 2.0 genes in this pathway |
RIZKI TUMOR INVASIVENESS 3D UP | 210 | 124 | All SZGR 2.0 genes in this pathway |
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING | 510 | 309 | All SZGR 2.0 genes in this pathway |
LABBE TGFB1 TARGETS DN | 108 | 64 | All SZGR 2.0 genes in this pathway |
LEE RECENT THYMIC EMIGRANT | 227 | 128 | All SZGR 2.0 genes in this pathway |
HAN SATB1 TARGETS DN | 442 | 275 | All SZGR 2.0 genes in this pathway |
CROONQUIST NRAS SIGNALING DN | 72 | 47 | All SZGR 2.0 genes in this pathway |
VALK AML CLUSTER 10 | 33 | 22 | All SZGR 2.0 genes in this pathway |
VALK AML WITH EVI1 | 25 | 15 | All SZGR 2.0 genes in this pathway |
CHIANG LIVER CANCER SUBCLASS CTNNB1 UP | 176 | 110 | All SZGR 2.0 genes in this pathway |
CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN | 193 | 112 | All SZGR 2.0 genes in this pathway |
YAGI AML WITH INV 16 TRANSLOCATION | 422 | 277 | All SZGR 2.0 genes in this pathway |
YAGI AML WITH 11Q23 REARRANGED | 351 | 238 | All SZGR 2.0 genes in this pathway |
ASGHARZADEH NEUROBLASTOMA POOR SURVIVAL DN | 46 | 30 | All SZGR 2.0 genes in this pathway |
HOSHIDA LIVER CANCER SUBCLASS S2 | 115 | 74 | All SZGR 2.0 genes in this pathway |
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP | 756 | 494 | All SZGR 2.0 genes in this pathway |
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP | 682 | 440 | All SZGR 2.0 genes in this pathway |
KIM ALL DISORDERS CALB1 CORR UP | 548 | 370 | All SZGR 2.0 genes in this pathway |
VERHAAK GLIOBLASTOMA NEURAL | 129 | 85 | All SZGR 2.0 genes in this pathway |
BILANGES SERUM SENSITIVE VIA TSC1 | 23 | 12 | All SZGR 2.0 genes in this pathway |
FEVR CTNNB1 TARGETS UP | 682 | 433 | All SZGR 2.0 genes in this pathway |
KOHOUTEK CCNT2 TARGETS | 58 | 35 | All SZGR 2.0 genes in this pathway |
PHONG TNF RESPONSE NOT VIA P38 | 337 | 236 | All SZGR 2.0 genes in this pathway |
LIM MAMMARY STEM CELL UP | 489 | 314 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | miRNA seq | ||
---|---|---|---|---|---|
UTR start | UTR end | Match method | |||
miR-124/506 | 1678 | 1684 | m8 | hsa-miR-506 | UAAGGCACCCUUCUGAGUAGA |
hsa-miR-124brain | UAAGGCACGCGGUGAAUGCC | ||||
miR-181 | 88 | 94 | 1A | hsa-miR-181abrain | AACAUUCAACGCUGUCGGUGAGU |
hsa-miR-181bSZ | AACAUUCAUUGCUGUCGGUGGG | ||||
hsa-miR-181cbrain | AACAUUCAACCUGUCGGUGAGU | ||||
hsa-miR-181dbrain | AACAUUCAUUGUUGUCGGUGGGUU | ||||
miR-19 | 549 | 555 | 1A | hsa-miR-19a | UGUGCAAAUCUAUGCAAAACUGA |
hsa-miR-19b | UGUGCAAAUCCAUGCAAAACUGA | ||||
miR-218 | 1816 | 1822 | m8 | hsa-miR-218brain | UUGUGCUUGAUCUAACCAUGU |
miR-320 | 426 | 433 | 1A,m8 | hsa-miR-320 | AAAAGCUGGGUUGAGAGGGCGAA |
miR-384 | 478 | 484 | 1A | hsa-miR-384 | AUUCCUAGAAAUUGUUCAUA |
miR-448 | 265 | 272 | 1A,m8 | hsa-miR-448 | UUGCAUAUGUAGGAUGUCCCAU |
miR-485-3p | 1748 | 1755 | 1A,m8 | hsa-miR-485-3p | GUCAUACACGGCUCUCCUCUCU |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.