Gene Page: SLC25A24
Summary ?
| GeneID | 29957 |
| Symbol | SLC25A24 |
| Synonyms | APC1|SCAMC-1 |
| Description | solute carrier family 25 member 24 |
| Reference | MIM:608744|HGNC:HGNC:20662|Ensembl:ENSG00000085491|HPRD:12290|Vega:OTTHUMG00000011013 |
| Gene type | protein-coding |
| Map location | 1p13.3 |
| Pascal p-value | 0.018 |
| eGene | Anterior cingulate cortex BA24 Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Nucleus accumbens basal ganglia Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs607101 | 1 | 108737302 | SLC25A24 | ENSG00000085491.11 | 1.188E-6 | 0.02 | 6169 | gtex_brain_ba24 |
| rs606640 | 1 | 108737425 | SLC25A24 | ENSG00000085491.11 | 1.136E-6 | 0.02 | 6046 | gtex_brain_ba24 |
| rs606166 | 1 | 108737551 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 5920 | gtex_brain_ba24 |
| rs200641468 | 1 | 108737805 | SLC25A24 | ENSG00000085491.11 | 2.421E-6 | 0.02 | 5666 | gtex_brain_ba24 |
| rs112727363 | 1 | 108737806 | SLC25A24 | ENSG00000085491.11 | 2.228E-6 | 0.02 | 5665 | gtex_brain_ba24 |
| rs505024 | 1 | 108738360 | SLC25A24 | ENSG00000085491.11 | 8.84E-7 | 0.02 | 5111 | gtex_brain_ba24 |
| rs591763 | 1 | 108738436 | SLC25A24 | ENSG00000085491.11 | 1.1E-6 | 0.02 | 5035 | gtex_brain_ba24 |
| rs589073 | 1 | 108739035 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 4436 | gtex_brain_ba24 |
| rs533233 | 1 | 108739104 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 4367 | gtex_brain_ba24 |
| rs685847 | 1 | 108739171 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 4300 | gtex_brain_ba24 |
| rs828992 | 1 | 108739214 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 4257 | gtex_brain_ba24 |
| rs828993 | 1 | 108739228 | SLC25A24 | ENSG00000085491.11 | 1.843E-6 | 0.02 | 4243 | gtex_brain_ba24 |
| rs34292729 | 1 | 108739434 | SLC25A24 | ENSG00000085491.11 | 1.126E-6 | 0.02 | 4037 | gtex_brain_ba24 |
| rs538717 | 1 | 108739705 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 3766 | gtex_brain_ba24 |
| rs594397 | 1 | 108741065 | SLC25A24 | ENSG00000085491.11 | 1.099E-6 | 0.02 | 2406 | gtex_brain_ba24 |
| rs662282 | 1 | 108742954 | SLC25A24 | ENSG00000085491.11 | 1.727E-6 | 0.02 | 517 | gtex_brain_ba24 |
| rs576805 | 1 | 108743042 | SLC25A24 | ENSG00000085491.11 | 1.03E-6 | 0.02 | 429 | gtex_brain_ba24 |
| rs577690 | 1 | 108743140 | SLC25A24 | ENSG00000085491.11 | 1.179E-6 | 0.02 | 331 | gtex_brain_ba24 |
| rs663481 | 1 | 108743178 | SLC25A24 | ENSG00000085491.11 | 1.18E-6 | 0.02 | 293 | gtex_brain_ba24 |
| rs12047398 | 1 | 108693305 | SLC25A24 | ENSG00000085491.11 | 6.031E-7 | 0 | 50166 | gtex_brain_putamen_basal |
| rs10494090 | 1 | 108693336 | SLC25A24 | ENSG00000085491.11 | 6.33E-7 | 0 | 50135 | gtex_brain_putamen_basal |
| rs35707205 | 1 | 108696516 | SLC25A24 | ENSG00000085491.11 | 6.491E-7 | 0 | 46955 | gtex_brain_putamen_basal |
| rs662590 | 1 | 108719572 | SLC25A24 | ENSG00000085491.11 | 2.003E-7 | 0 | 23899 | gtex_brain_putamen_basal |
| rs646578 | 1 | 108723809 | SLC25A24 | ENSG00000085491.11 | 1.973E-7 | 0 | 19662 | gtex_brain_putamen_basal |
| rs58480591 | 1 | 108733296 | SLC25A24 | ENSG00000085491.11 | 8.795E-7 | 0 | 10175 | gtex_brain_putamen_basal |
| rs497819 | 1 | 108734695 | SLC25A24 | ENSG00000085491.11 | 5.493E-7 | 0 | 8776 | gtex_brain_putamen_basal |
| rs607101 | 1 | 108737302 | SLC25A24 | ENSG00000085491.11 | 3.838E-9 | 0 | 6169 | gtex_brain_putamen_basal |
| rs606640 | 1 | 108737425 | SLC25A24 | ENSG00000085491.11 | 3.764E-9 | 0 | 6046 | gtex_brain_putamen_basal |
| rs606166 | 1 | 108737551 | SLC25A24 | ENSG00000085491.11 | 3.905E-9 | 0 | 5920 | gtex_brain_putamen_basal |
| rs200641468 | 1 | 108737805 | SLC25A24 | ENSG00000085491.11 | 7.465E-8 | 0 | 5666 | gtex_brain_putamen_basal |
| rs112727363 | 1 | 108737806 | SLC25A24 | ENSG00000085491.11 | 3.925E-8 | 0 | 5665 | gtex_brain_putamen_basal |
| rs505024 | 1 | 108738360 | SLC25A24 | ENSG00000085491.11 | 3.773E-9 | 0 | 5111 | gtex_brain_putamen_basal |
| rs591763 | 1 | 108738436 | SLC25A24 | ENSG00000085491.11 | 3.762E-9 | 0 | 5035 | gtex_brain_putamen_basal |
| rs589073 | 1 | 108739035 | SLC25A24 | ENSG00000085491.11 | 3.693E-9 | 0 | 4436 | gtex_brain_putamen_basal |
| rs533233 | 1 | 108739104 | SLC25A24 | ENSG00000085491.11 | 3.692E-9 | 0 | 4367 | gtex_brain_putamen_basal |
| rs685847 | 1 | 108739171 | SLC25A24 | ENSG00000085491.11 | 3.691E-9 | 0 | 4300 | gtex_brain_putamen_basal |
| rs828992 | 1 | 108739214 | SLC25A24 | ENSG00000085491.11 | 3.691E-9 | 0 | 4257 | gtex_brain_putamen_basal |
| rs828993 | 1 | 108739228 | SLC25A24 | ENSG00000085491.11 | 1.339E-9 | 0 | 4243 | gtex_brain_putamen_basal |
| rs34292729 | 1 | 108739434 | SLC25A24 | ENSG00000085491.11 | 3.663E-9 | 0 | 4037 | gtex_brain_putamen_basal |
| rs538717 | 1 | 108739705 | SLC25A24 | ENSG00000085491.11 | 3.689E-9 | 0 | 3766 | gtex_brain_putamen_basal |
| rs34148137 | 1 | 108739726 | SLC25A24 | ENSG00000085491.11 | 7.182E-8 | 0 | 3745 | gtex_brain_putamen_basal |
| rs676166 | 1 | 108739849 | SLC25A24 | ENSG00000085491.11 | 1.644E-8 | 0 | 3622 | gtex_brain_putamen_basal |
| rs828994 | 1 | 108740419 | SLC25A24 | ENSG00000085491.11 | 1.644E-8 | 0 | 3052 | gtex_brain_putamen_basal |
| rs828995 | 1 | 108740779 | SLC25A24 | ENSG00000085491.11 | 2.802E-7 | 0 | 2692 | gtex_brain_putamen_basal |
| rs594397 | 1 | 108741065 | SLC25A24 | ENSG00000085491.11 | 3.771E-9 | 0 | 2406 | gtex_brain_putamen_basal |
| rs554709 | 1 | 108742892 | SLC25A24 | ENSG00000085491.11 | 2.828E-8 | 0 | 579 | gtex_brain_putamen_basal |
| rs662282 | 1 | 108742954 | SLC25A24 | ENSG00000085491.11 | 4.44E-9 | 0 | 517 | gtex_brain_putamen_basal |
| rs576805 | 1 | 108743042 | SLC25A24 | ENSG00000085491.11 | 4.272E-9 | 0 | 429 | gtex_brain_putamen_basal |
| rs577690 | 1 | 108743140 | SLC25A24 | ENSG00000085491.11 | 4.223E-9 | 0 | 331 | gtex_brain_putamen_basal |
| rs663481 | 1 | 108743178 | SLC25A24 | ENSG00000085491.11 | 4.226E-9 | 0 | 293 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 3 4WK UP | 214 | 144 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 5 6WK UP | 116 | 68 | All SZGR 2.0 genes in this pathway |
| SEIDEN ONCOGENESIS BY MET | 88 | 53 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS DN | 848 | 527 | All SZGR 2.0 genes in this pathway |
| LIU BREAST CANCER | 30 | 19 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| CERVERA SDHB TARGETS 1 UP | 118 | 66 | All SZGR 2.0 genes in this pathway |
| SHEPARD BMYB MORPHOLINO DN | 200 | 112 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 4 | 307 | 185 | All SZGR 2.0 genes in this pathway |
| HOWLIN CITED1 TARGETS 1 DN | 37 | 22 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| MARSON FOXP3 TARGETS STIMULATED UP | 29 | 19 | All SZGR 2.0 genes in this pathway |
| BOYERINAS ONCOFETAL TARGETS OF LET7A1 | 12 | 9 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL TUMOR UP | 294 | 199 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL CARCINOMA VS ADENOMA DN | 24 | 18 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA C D DN | 252 | 155 | All SZGR 2.0 genes in this pathway |
| CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA PCA1 UP | 101 | 66 | All SZGR 2.0 genes in this pathway |
| DUTERTRE ESTRADIOL RESPONSE 6HR UP | 229 | 149 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |
| PASINI SUZ12 TARGETS DN | 315 | 215 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |
| ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP | 289 | 184 | All SZGR 2.0 genes in this pathway |
| ZWANG EGF INTERVAL UP | 105 | 46 | All SZGR 2.0 genes in this pathway |