Summary ?
GeneID3119
SymbolHLA-DQB1
SynonymsCELIAC1|HLA-DQB|IDDM1
Descriptionmajor histocompatibility complex, class II, DQ beta 1
ReferenceMIM:604305|HGNC:HGNC:4944|Ensembl:ENSG00000179344|HPRD:05054|Vega:OTTHUMG00000031124
Gene typeprotein-coding
Map location6p21.3
Sherlock p-value0.074
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWAScatGenome-wide Association StudiesThis data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_IGenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs3130287chr632050543HLA-DQB131190.12cis
rs3130284chr632140486HLA-DQB131190.02cis
rs2071278chr632165443HLA-DQB131190.06cis
rs3131294chr632180145HLA-DQB131191.351E-4cis
rs3129933chr632336160HLA-DQB131190.04cis
rs3129934chr632336186HLA-DQB131190.19cis
rs7749092chr632449049HLA-DQB131190.03cis
rs9270986chr632574059HLA-DQB131191.444E-5cis
rs9273363chr632626271HLA-DQB131190.06cis
rs9275765chr632689323HLA-DQB131190.11cis
rs9275772chr632689502HLA-DQB131190.15cis
rs6920921chr68884160HLA-DQB131190.13trans
rs3131294chr632180145HLA-DQB131190.01trans
rs9270986chr632574059HLA-DQB131190trans
rs2892394chr101740277HLA-DQB131190.16trans
rs17089379chr1364433308HLA-DQB131190.17trans
rs6098195chr2053340297HLA-DQB131190.13trans
rs6098196chr2053340365HLA-DQB131190.14trans
rs6091960chr2053343341HLA-DQB131190.08trans
rs6098208chr2053343571HLA-DQB131190.13trans
rs4555403chr2053396896HLA-DQB131190.18trans
rs3131291632184066HLA-DQB1ENSG00000179344.124.307E-70452094gtex_brain_ba24
rs3096703632184094HLA-DQB1ENSG00000179344.124.267E-70452066gtex_brain_ba24
rs3134799632184221HLA-DQB1ENSG00000179344.124.122E-70451939gtex_brain_ba24
rs541410751632185922HLA-DQB1ENSG00000179344.124.122E-70450238gtex_brain_ba24
rs3134797632186050HLA-DQB1ENSG00000179344.124.122E-70450110gtex_brain_ba24
rs9268072632232652HLA-DQB1ENSG00000179344.126.596E-80403508gtex_brain_ba24
rs9268118632249987HLA-DQB1ENSG00000179344.122.051E-70386173gtex_brain_ba24
rs9268149632263099HLA-DQB1ENSG00000179344.122.367E-70373061gtex_brain_ba24
rs9268155632266310HLA-DQB1ENSG00000179344.121.634E-70369850gtex_brain_ba24
rs6920338632288089HLA-DQB1ENSG00000179344.122.412E-70348071gtex_brain_ba24
rs7451330632295965HLA-DQB1ENSG00000179344.122.412E-70340195gtex_brain_ba24
rs3117117632321272HLA-DQB1ENSG00000179344.122.412E-70314888gtex_brain_ba24
rs9281766632338620HLA-DQB1ENSG00000179344.128.288E-70297540gtex_brain_ba24
rs3135384632419959HLA-DQB1ENSG00000179344.121.416E-70216201gtex_brain_ba24
rs3129895632421227HLA-DQB1ENSG00000179344.121.824E-70214933gtex_brain_ba24
rs3129898632422125HLA-DQB1ENSG00000179344.121.714E-70214035gtex_brain_ba24
rs9268807632423915HLA-DQB1ENSG00000179344.121.814E-70212245gtex_brain_ba24
rs9268851632429582HLA-DQB1ENSG00000179344.121.331E-70206578gtex_brain_ba24
rs9268927632433085HLA-DQB1ENSG00000179344.121.329E-70203075gtex_brain_ba24
rs9268978632434978HLA-DQB1ENSG00000179344.121.329E-70201182gtex_brain_ba24
rs9269047632438783HLA-DQB1ENSG00000179344.121.294E-70197377gtex_brain_ba24
rs62405567632453372HLA-DQB1ENSG00000179344.128.914E-70182788gtex_brain_ba24
rs536151678632453543HLA-DQB1ENSG00000179344.121.178E-70182617gtex_brain_ba24
rs571840751632453831HLA-DQB1ENSG00000179344.125.709E-70182329gtex_brain_ba24
rs151209291632455089HLA-DQB1ENSG00000179344.127.063E-70181071gtex_brain_ba24
rs114007941632459031HLA-DQB1ENSG00000179344.128.561E-70177129gtex_brain_ba24
rs75785630632459419HLA-DQB1ENSG00000179344.128.913E-70176741gtex_brain_ba24
rs72849291632479924HLA-DQB1ENSG00000179344.124.738E-70156236gtex_brain_ba24
rs75336735632480546HLA-DQB1ENSG00000179344.125.744E-70155614gtex_brain_ba24
rs112709708632482316HLA-DQB1ENSG00000179344.127.18E-70153844gtex_brain_ba24
rs111537693632482481HLA-DQB1ENSG00000179344.127.521E-70153679gtex_brain_ba24
rs113965088632486456HLA-DQB1ENSG00000179344.124.099E-80149704gtex_brain_ba24
rs73405151632486756HLA-DQB1ENSG00000179344.122.775E-70149404gtex_brain_ba24
rs72508437632488132HLA-DQB1ENSG00000179344.121.547E-70148028gtex_brain_ba24
rs143375763632488545HLA-DQB1ENSG00000179344.122.564E-70147615gtex_brain_ba24
rs191239464632488845HLA-DQB1ENSG00000179344.121.446E-70147315gtex_brain_ba24
rs35507994632489117HLA-DQB1ENSG00000179344.122.132E-80147043gtex_brain_ba24
rs189059541632489501HLA-DQB1ENSG00000179344.128.776E-70146659gtex_brain_ba24
rs149025589632490000HLA-DQB1ENSG00000179344.121.887E-80146160gtex_brain_ba24
rs112784054632490282HLA-DQB1ENSG00000179344.125.604E-70145878gtex_brain_ba24
rs113934686632491971HLA-DQB1ENSG00000179344.126.847E-70144189gtex_brain_ba24
rs146711239632495746HLA-DQB1ENSG00000179344.121.25E-70140414gtex_brain_ba24
rs62405579632498134HLA-DQB1ENSG00000179344.127.543E-70138026gtex_brain_ba24
rs16870187632498584HLA-DQB1ENSG00000179344.125.924E-70137576gtex_brain_ba24
rs78569932632498885HLA-DQB1ENSG00000179344.125.762E-80137275gtex_brain_ba24
rs111596400632499154HLA-DQB1ENSG00000179344.123.474E-70137006gtex_brain_ba24
rs113972770632501169HLA-DQB1ENSG00000179344.122.296E-70134991gtex_brain_ba24
rs28568890632505767HLA-DQB1ENSG00000179344.122.704E-80130393gtex_brain_ba24
rs59894631632505869HLA-DQB1ENSG00000179344.128.771E-90130291gtex_brain_ba24
rs74949117632506846HLA-DQB1ENSG00000179344.127.661E-70129314gtex_brain_ba24
rs67322126632507759HLA-DQB1ENSG00000179344.122.137E-70128401gtex_brain_ba24
rs574680805632508136HLA-DQB1ENSG00000179344.122.138E-70128024gtex_brain_ba24
rs66857824632512539HLA-DQB1ENSG00000179344.129.716E-80123621gtex_brain_ba24
rs71534541632513076HLA-DQB1ENSG00000179344.121.03E-70123084gtex_brain_ba24
rs34442507632513531HLA-DQB1ENSG00000179344.129.795E-80122629gtex_brain_ba24
rs35997662632513575HLA-DQB1ENSG00000179344.123.352E-80122585gtex_brain_ba24
rs34791134632513714HLA-DQB1ENSG00000179344.122.64E-80122446gtex_brain_ba24
rs33998225632513883HLA-DQB1ENSG00000179344.129.528E-80122277gtex_brain_ba24
rs73395560632514671HLA-DQB1ENSG00000179344.121.024E-70121489gtex_brain_ba24
rs61362782632517084HLA-DQB1ENSG00000179344.127.073E-70119076gtex_brain_ba24
rs66468365632518310HLA-DQB1ENSG00000179344.123.523E-70117850gtex_brain_ba24
rs370702093632519338HLA-DQB1ENSG00000179344.123.855E-70116822gtex_brain_ba24
rs35455030632522650HLA-DQB1ENSG00000179344.129.657E-80113510gtex_brain_ba24
rs35222480632522813HLA-DQB1ENSG00000179344.121.079E-70113347gtex_brain_ba24
rs35058673632523008HLA-DQB1ENSG00000179344.121.041E-70113152gtex_brain_ba24
rs72492333632523401HLA-DQB1ENSG00000179344.126.307E-70112759gtex_brain_ba24
rs185753700632524635HLA-DQB1ENSG00000179344.127.392E-70111525gtex_brain_ba24
rs116267317632524929HLA-DQB1ENSG00000179344.128.462E-70111231gtex_brain_ba24
rs28671583632525327HLA-DQB1ENSG00000179344.124.145E-70110833gtex_brain_ba24
rs28534491632526396HLA-DQB1ENSG00000179344.126.614E-90109764gtex_brain_ba24
rs28624072632527296HLA-DQB1ENSG00000179344.121.724E-90108864gtex_brain_ba24
rs34382945632537290HLA-DQB1ENSG00000179344.129.195E-9098870gtex_brain_ba24
rs58942228632538272HLA-DQB1ENSG00000179344.125.96E-8097888gtex_brain_ba24
rs72847631632538650HLA-DQB1ENSG00000179344.125.453E-7097510gtex_brain_ba24
rs9269350632540548HLA-DQB1ENSG00000179344.125.703E-7095612gtex_brain_ba24
rs76924329632541094HLA-DQB1ENSG00000179344.126.842E-7095066gtex_brain_ba24
rs9269419632541506HLA-DQB1ENSG00000179344.124.633E-8094654gtex_brain_ba24
rs9281855632541593HLA-DQB1ENSG00000179344.121.86E-7094567gtex_brain_ba24
rs9269571632544650HLA-DQB1ENSG00000179344.128.387E-7091510gtex_brain_ba24
rs9269573632544697HLA-DQB1ENSG00000179344.121.385E-8091463gtex_brain_ba24
rs9269579632544772HLA-DQB1ENSG00000179344.128.595E-7091388gtex_brain_ba24
rs9269583632544799HLA-DQB1ENSG00000179344.123.996E-8091361gtex_brain_ba24
rs9269795632549259HLA-DQB1ENSG00000179344.123.831E-7086901gtex_brain_ba24
rs9269840632550150HLA-DQB1ENSG00000179344.124.008E-7086010gtex_brain_ba24
rs9269841632550164HLA-DQB1ENSG00000179344.123.955E-7085996gtex_brain_ba24
rs9269868632550702HLA-DQB1ENSG00000179344.124.003E-7085458gtex_brain_ba24
rs9269869632550715HLA-DQB1ENSG00000179344.123.96E-7085445gtex_brain_ba24
rs35830505632551022HLA-DQB1ENSG00000179344.127.645E-8085138gtex_brain_ba24
rs9269892632551054HLA-DQB1ENSG00000179344.126.466E-8085106gtex_brain_ba24
rs9269893632551058HLA-DQB1ENSG00000179344.125.883E-8085102gtex_brain_ba24
rs9269895632551068HLA-DQB1ENSG00000179344.125.796E-8085092gtex_brain_ba24
rs9269898632551126HLA-DQB1ENSG00000179344.124.344E-7085034gtex_brain_ba24
rs9269901632551192HLA-DQB1ENSG00000179344.129.626E-7084968gtex_brain_ba24
rs9269902632551197HLA-DQB1ENSG00000179344.126.006E-7084963gtex_brain_ba24
rs9269938632551853HLA-DQB1ENSG00000179344.124.392E-8084307gtex_brain_ba24
rs9270187632555965HLA-DQB1ENSG00000179344.123.411E-8080195gtex_brain_ba24
rs9270189632556030HLA-DQB1ENSG00000179344.124.488E-8080130gtex_brain_ba24
rs199625001632556155HLA-DQB1ENSG00000179344.124.48E-7080005gtex_brain_ba24
rs9270299632557435HLA-DQB1ENSG00000179344.121.77E-7078725gtex_brain_ba24
rs9270402632558429HLA-DQB1ENSG00000179344.121.043E-8077731gtex_brain_ba24
rs371863646632559850HLA-DQB1ENSG00000179344.123.5E-8076310gtex_brain_ba24
rs9270643632565721HLA-DQB1ENSG00000179344.126.879E-7070439gtex_brain_ba24
rs9270700632567306HLA-DQB1ENSG00000179344.129.175E-7068854gtex_brain_ba24
rs9270707632567351HLA-DQB1ENSG00000179344.126.92E-8068809gtex_brain_ba24
rs9270717632567506HLA-DQB1ENSG00000179344.127.814E-7068654gtex_brain_ba24
rs9270880632571659HLA-DQB1ENSG00000179344.127.976E-7064501gtex_brain_ba24
rs4478449632571801HLA-DQB1ENSG00000179344.128.068E-7064359gtex_brain_ba24
rs9271065632575619HLA-DQB1ENSG00000179344.122.364E-8060541gtex_brain_ba24
rs9271069632575700HLA-DQB1ENSG00000179344.122.623E-8060460gtex_brain_ba24
rs9271126632576873HLA-DQB1ENSG00000179344.129.072E-7059287gtex_brain_ba24
rs9271176632578127HLA-DQB1ENSG00000179344.125.621E-7058033gtex_brain_ba24
rs9271222632579365HLA-DQB1ENSG00000179344.122.042E-8056795gtex_brain_ba24
rs3997873632580723HLA-DQB1ENSG00000179344.123.045E-8055437gtex_brain_ba24
rs9271347632583543HLA-DQB1ENSG00000179344.123.045E-8052617gtex_brain_ba24
rs541562974632583830HLA-DQB1ENSG00000179344.123.364E-8052330gtex_brain_ba24
rs9271351632583860HLA-DQB1ENSG00000179344.123.045E-8052300gtex_brain_ba24
rs9271353632584014HLA-DQB1ENSG00000179344.123.045E-8052146gtex_brain_ba24
rs9271354632584066HLA-DQB1ENSG00000179344.123.045E-8052094gtex_brain_ba24
rs3129757632584609HLA-DQB1ENSG00000179344.123.045E-8051551gtex_brain_ba24
rs3129758632584625HLA-DQB1ENSG00000179344.121.049E-7051535gtex_brain_ba24
rs3129762632585755HLA-DQB1ENSG00000179344.122.333E-8050405gtex_brain_ba24
rs3135005632586019HLA-DQB1ENSG00000179344.123.045E-8050141gtex_brain_ba24
rs9271366632586854HLA-DQB1ENSG00000179344.123.045E-8049306gtex_brain_ba24
rs9271374632587041HLA-DQB1ENSG00000179344.121.451E-7049119gtex_brain_ba24
rs9271376632587113HLA-DQB1ENSG00000179344.126.916E-10049047gtex_brain_ba24
rs9271413632587768HLA-DQB1ENSG00000179344.123.045E-8048392gtex_brain_ba24
rs9271421632587859HLA-DQB1ENSG00000179344.122.271E-8048301gtex_brain_ba24
rs9271423632587897HLA-DQB1ENSG00000179344.123.045E-8048263gtex_brain_ba24
rs9271481632588877HLA-DQB1ENSG00000179344.123.129E-8047283gtex_brain_ba24
rs562478082632590362HLA-DQB1ENSG00000179344.123.045E-8045798gtex_brain_ba24
rs4959030632591751HLA-DQB1ENSG00000179344.122.517E-9044409gtex_brain_ba24
rs4959108632591922HLA-DQB1ENSG00000179344.125.004E-9044238gtex_brain_ba24
rs9271687632592985HLA-DQB1ENSG00000179344.125.004E-9043175gtex_brain_ba24
rs9271710632593421HLA-DQB1ENSG00000179344.122.427E-9042739gtex_brain_ba24
rs9271775632594328HLA-DQB1ENSG00000179344.124.507E-7041832gtex_brain_ba24
rs3104392632594425HLA-DQB1ENSG00000179344.125.004E-9041735gtex_brain_ba24
rs3104391632594901HLA-DQB1ENSG00000179344.125.131E-9041259gtex_brain_ba24
rs9271874632595424HLA-DQB1ENSG00000179344.121.097E-7040736gtex_brain_ba24
rs3104376632600003HLA-DQB1ENSG00000179344.126.43E-9036157gtex_brain_ba24
rs3104373632600375HLA-DQB1ENSG00000179344.123.894E-9035785gtex_brain_ba24
rs3104369632602482HLA-DQB1ENSG00000179344.122.3E-7033678gtex_brain_ba24
rs3104367632603487HLA-DQB1ENSG00000179344.122.641E-8032673gtex_brain_ba24
rs3104364632603968HLA-DQB1ENSG00000179344.122.656E-8032192gtex_brain_ba24
rs3104363632604000HLA-DQB1ENSG00000179344.122.534E-8032160gtex_brain_ba24
rs9272320632604124HLA-DQB1ENSG00000179344.126.833E-7032036gtex_brain_ba24
rs9272330632604213HLA-DQB1ENSG00000179344.127.468E-8031947gtex_brain_ba24
rs574479978632604332HLA-DQB1ENSG00000179344.123.495E-8031828gtex_brain_ba24
rs9272346632604372HLA-DQB1ENSG00000179344.122.354E-8031788gtex_brain_ba24
rs9272350632604410HLA-DQB1ENSG00000179344.123.401E-8031750gtex_brain_ba24
rs9272355632604515HLA-DQB1ENSG00000179344.122.568E-8031645gtex_brain_ba24
rs9272357632604522HLA-DQB1ENSG00000179344.123.697E-8031638gtex_brain_ba24
rs9272367632604625HLA-DQB1ENSG00000179344.121.819E-8031535gtex_brain_ba24
rs9272377632604699HLA-DQB1ENSG00000179344.129.536E-7031461gtex_brain_ba24
rs9272379632604727HLA-DQB1ENSG00000179344.128.74E-7031433gtex_brain_ba24
rs9272387632604776HLA-DQB1ENSG00000179344.121.81E-8031384gtex_brain_ba24
rs9272389632604793HLA-DQB1ENSG00000179344.121.781E-8031367gtex_brain_ba24
rs9272393632604826HLA-DQB1ENSG00000179344.124.802E-8031334gtex_brain_ba24
rs9272416632605043HLA-DQB1ENSG00000179344.122.578E-8031117gtex_brain_ba24
rs3187964632605207HLA-DQB1ENSG00000179344.124.502E-8030953gtex_brain_ba24
rs1047989632605257HLA-DQB1ENSG00000179344.126.706E-7030903gtex_brain_ba24
rs1130034632605274HLA-DQB1ENSG00000179344.122.904E-8030886gtex_brain_ba24
rs9272441632605380HLA-DQB1ENSG00000179344.122.58E-8030780gtex_brain_ba24
rs9272442632605400HLA-DQB1ENSG00000179344.122.572E-8030760gtex_brain_ba24
rs7751376632605437HLA-DQB1ENSG00000179344.123.699E-8030723gtex_brain_ba24
rs9272454632605525HLA-DQB1ENSG00000179344.121.469E-7030635gtex_brain_ba24
rs9272468632605708HLA-DQB1ENSG00000179344.122.381E-8030452gtex_brain_ba24
rs9272473632605738HLA-DQB1ENSG00000179344.123.635E-8030422gtex_brain_ba24
rs9272474632605754HLA-DQB1ENSG00000179344.123.728E-8030406gtex_brain_ba24
rs9272482632605920HLA-DQB1ENSG00000179344.123.003E-8030240gtex_brain_ba24
rs9272484632605943HLA-DQB1ENSG00000179344.123.008E-8030217gtex_brain_ba24
rs9272488632606005HLA-DQB1ENSG00000179344.122.468E-8030155gtex_brain_ba24
rs9272491632606046HLA-DQB1ENSG00000179344.123.335E-8030114gtex_brain_ba24
rs9272494632606085HLA-DQB1ENSG00000179344.123.672E-8030075gtex_brain_ba24
rs9272497632606176HLA-DQB1ENSG00000179344.122.623E-8029984gtex_brain_ba24
rs9272502632606244HLA-DQB1ENSG00000179344.121.225E-8029916gtex_brain_ba24
rs9272513632606380HLA-DQB1ENSG00000179344.124.38E-8029780gtex_brain_ba24
rs9272515632606406HLA-DQB1ENSG00000179344.123.064E-7029754gtex_brain_ba24
rs4530904632606444HLA-DQB1ENSG00000179344.123.034E-9029716gtex_brain_ba24
rs9272528632606617HLA-DQB1ENSG00000179344.121.288E-8029543gtex_brain_ba24
rs9272538632606809HLA-DQB1ENSG00000179344.121.014E-8029351gtex_brain_ba24
rs9272540632606834HLA-DQB1ENSG00000179344.123.863E-8029326gtex_brain_ba24
rs9272553632607008HLA-DQB1ENSG00000179344.123.631E-8029152gtex_brain_ba24
rs9279894632607036HLA-DQB1ENSG00000179344.123.557E-8029124gtex_brain_ba24
rs9272555632607042HLA-DQB1ENSG00000179344.123.857E-8029118gtex_brain_ba24
rs9272563632607158HLA-DQB1ENSG00000179344.121.162E-7029002gtex_brain_ba24
rs9272565632607169HLA-DQB1ENSG00000179344.121.161E-7028991gtex_brain_ba24
rs9272567632607200HLA-DQB1ENSG00000179344.121.172E-7028960gtex_brain_ba24
rs9272568632607209HLA-DQB1ENSG00000179344.121.172E-7028951gtex_brain_ba24
rs28383378632607239HLA-DQB1ENSG00000179344.123.196E-7028921gtex_brain_ba24
rs9272574632607281HLA-DQB1ENSG00000179344.122.419E-8028879gtex_brain_ba24
rs9272583632607453HLA-DQB1ENSG00000179344.122.81E-8028707gtex_brain_ba24
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rs2858310632668323HLA-DQB1ENSG00000179344.121.54E-70-32163gtex_brain_putamen_basal
rs2647046632668336HLA-DQB1ENSG00000179344.121.54E-70-32176gtex_brain_putamen_basal
rs3135002632668439HLA-DQB1ENSG00000179344.122.029E-120-32279gtex_brain_putamen_basal
rs2858309632668713HLA-DQB1ENSG00000179344.121.54E-70-32553gtex_brain_putamen_basal
rs1612904632669018HLA-DQB1ENSG00000179344.124.859E-80-32858gtex_brain_putamen_basal
rs3135001632670136HLA-DQB1ENSG00000179344.127.294E-150-33976gtex_brain_putamen_basal
rs2856717632670308HLA-DQB1ENSG00000179344.121.54E-70-34148gtex_brain_putamen_basal
rs2858305632670464HLA-DQB1ENSG00000179344.121.54E-70-34304gtex_brain_putamen_basal
rs2647051632670897HLA-DQB1ENSG00000179344.121.54E-70-34737gtex_brain_putamen_basal
rs2856699632671765HLA-DQB1ENSG00000179344.121.54E-70-35605gtex_brain_putamen_basal
rs3134997632672039HLA-DQB1ENSG00000179344.125.072E-120-35879gtex_brain_putamen_basal
rs3134995632672089HLA-DQB1ENSG00000179344.124.093E-140-35929gtex_brain_putamen_basal
.632672463HLA-DQB1ENSG00000179344.127.294E-150-36303gtex_brain_putamen_basal
rs3134969632674027HLA-DQB1ENSG00000179344.128.784E-120-37867gtex_brain_putamen_basal
rs3134968632674059HLA-DQB1ENSG00000179344.121.961E-120-37899gtex_brain_putamen_basal
rs3134966632674298HLA-DQB1ENSG00000179344.121.211E-140-38138gtex_brain_putamen_basal
rs9275521632674952HLA-DQB1ENSG00000179344.121.54E-70-38792gtex_brain_putamen_basal
rs527493854632675902HLA-DQB1ENSG00000179344.124.823E-80-39742gtex_brain_putamen_basal
rs3129721632676251HLA-DQB1ENSG00000179344.124.859E-80-40091gtex_brain_putamen_basal
rs4947344632677846HLA-DQB1ENSG00000179344.125.189E-100-41686gtex_brain_putamen_basal
rs3129726632678206HLA-DQB1ENSG00000179344.127.294E-150-42046gtex_brain_putamen_basal
rs4947345632678260HLA-DQB1ENSG00000179344.121.54E-70-42100gtex_brain_putamen_basal
rs3135461632680122HLA-DQB1ENSG00000179344.121.371E-100-43962gtex_brain_putamen_basal
rs9275596632681631HLA-DQB1ENSG00000179344.124.859E-80-45471gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0032395MHC class II receptor activityNAS2998758 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002504antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEA-
GO:0006955immune responseIEA-
GO:0006955immune responseNAS2998758 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016020membraneNAS2998758 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneEXP11048639 |11827988 |15489916 
|17652306 
GO:0042613MHC class II protein complexIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG CELL ADHESION MOLECULES CAMS 13493All SZGR 2.0 genes in this pathway
KEGG ANTIGEN PROCESSING AND PRESENTATION 8965All SZGR 2.0 genes in this pathway
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION 4836All SZGR 2.0 genes in this pathway
KEGG TYPE I DIABETES MELLITUS 4438All SZGR 2.0 genes in this pathway
KEGG LEISHMANIA INFECTION 7256All SZGR 2.0 genes in this pathway
KEGG ASTHMA 3025All SZGR 2.0 genes in this pathway
KEGG AUTOIMMUNE THYROID DISEASE 5349All SZGR 2.0 genes in this pathway
KEGG SYSTEMIC LUPUS ERYTHEMATOSUS 140100All SZGR 2.0 genes in this pathway
KEGG ALLOGRAFT REJECTION 3834All SZGR 2.0 genes in this pathway
KEGG GRAFT VERSUS HOST DISEASE 4231All SZGR 2.0 genes in this pathway
KEGG VIRAL MYOCARDITIS 7358All SZGR 2.0 genes in this pathway
SCHUETZ BREAST CANCER DUCTAL INVASIVE UP 351230All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE UP 423283All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER ADVANCED VS EARLY UP 175120All SZGR 2.0 genes in this pathway
BOGNI TREATMENT RELATED MYELOID LEUKEMIA DN 3319All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE DN 5438All SZGR 2.0 genes in this pathway
ODONNELL TFRC TARGETS UP 456228All SZGR 2.0 genes in this pathway
ODONNELL TARGETS OF MYC AND TFRC UP 8350All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL QUIESCENT DN 4732All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL DIVIDING DN 126All SZGR 2.0 genes in this pathway
GRAHAM CML DIVIDING VS NORMAL DIVIDING DN 106All SZGR 2.0 genes in this pathway
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN 9557All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781465All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES SKIN DN 2720All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES DN 1610All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 4 5WK UP 271175All SZGR 2.0 genes in this pathway
HUMMERICH SKIN CANCER PROGRESSION UP 8858All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392251All SZGR 2.0 genes in this pathway
LUI THYROID CANCER CLUSTER 4 169All SZGR 2.0 genes in this pathway
TERAMOTO OPN TARGETS CLUSTER 7 1916All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER D 3714All SZGR 2.0 genes in this pathway
PETRETTO HEART MASS QTL CIS DN 2415All SZGR 2.0 genes in this pathway
KLEIN PRIMARY EFFUSION LYMPHOMA DN 5842All SZGR 2.0 genes in this pathway
WIELAND UP BY HBV INFECTION 10166All SZGR 2.0 genes in this pathway
SANA RESPONSE TO IFNG UP 7850All SZGR 2.0 genes in this pathway
YAO HOXA10 TARGETS VIA PROGESTERONE UP 7958All SZGR 2.0 genes in this pathway
BROWN MYELOID CELL DEVELOPMENT DN 12986All SZGR 2.0 genes in this pathway
YU MYC TARGETS DN 5538All SZGR 2.0 genes in this pathway
LENAOUR DENDRITIC CELL MATURATION UP 11484All SZGR 2.0 genes in this pathway
BASSO CD40 SIGNALING UP 10176All SZGR 2.0 genes in this pathway
GEORGANTAS HSC MARKERS 7147All SZGR 2.0 genes in this pathway
MCLACHLAN DENTAL CARIES DN 245144All SZGR 2.0 genes in this pathway
LEE AGING CEREBELLUM UP 8458All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487303All SZGR 2.0 genes in this pathway
NIELSEN LEIOMYOSARCOMA UP 1810All SZGR 2.0 genes in this pathway
MCLACHLAN DENTAL CARIES UP 253147All SZGR 2.0 genes in this pathway
KIM LRRC3B TARGETS 3024All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY GAMMA RADIATION 8159All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE UP 226164All SZGR 2.0 genes in this pathway
HELLER SILENCED BY METHYLATION UP 282183All SZGR 2.0 genes in this pathway
WALLACE PROSTATE CANCER RACE UP 299167All SZGR 2.0 genes in this pathway
IWANAGA CARCINOGENESIS BY KRAS PTEN DN 353226All SZGR 2.0 genes in this pathway
SMID BREAST CANCER RELAPSE IN PLEURA DN 2715All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B DN 564326All SZGR 2.0 genes in this pathway
SMID BREAST CANCER NORMAL LIKE UP 476285All SZGR 2.0 genes in this pathway
GAURNIER PSMD4 TARGETS 7355All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL DN 216143All SZGR 2.0 genes in this pathway
BREDEMEYER RAG SIGNALING VIA ATM NOT VIA NFKB DN 3823All SZGR 2.0 genes in this pathway
WINTER HYPOXIA METAGENE 242168All SZGR 2.0 genes in this pathway
CROMER TUMORIGENESIS DN 5129All SZGR 2.0 genes in this pathway
BEIER GLIOMA STEM CELL DN 6642All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA D UP 8962All SZGR 2.0 genes in this pathway
WU SILENCED BY METHYLATION IN BLADDER CANCER 5542All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE 346192All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP 10767All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP 13179All SZGR 2.0 genes in this pathway
WUNDER INFLAMMATORY RESPONSE AND CHOLESTEROL UP 5838All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS UP 491316All SZGR 2.0 genes in this pathway
HOFFMANN PRE BI TO LARGE PRE BII LYMPHOCYTE UP 3624All SZGR 2.0 genes in this pathway
HOFFMANN LARGE TO SMALL PRE BII LYMPHOCYTE UP 163102All SZGR 2.0 genes in this pathway
HOFFMANN SMALL PRE BII TO IMMATURE B LYMPHOCYTE UP 7049All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES 389245All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE UP 181106All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION 368247All SZGR 2.0 genes in this pathway
WINNEPENNINCKX MELANOMA METASTASIS DN 4626All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S1 237159All SZGR 2.0 genes in this pathway
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP 7646All SZGR 2.0 genes in this pathway
KIM GLIS2 TARGETS UP 8461All SZGR 2.0 genes in this pathway
FOSTER KDM1A TARGETS UP 266142All SZGR 2.0 genes in this pathway