Gene Page: HSPA1A

Summary
GeneID  3303
Symbol  HSPA1A
Synonyms  FLJ54303|FLJ54370|FLJ54392|FLJ54408|FLJ75127|HSP70-1|HSP70-1A|HSP70I|HSP72|HSPA1|HSPA1B
Description  heat shock 70kDa protein 1A
See related  HGNC:5232|MIM:140550|Ensembl:ENSG00000204389|HPRD:00774|
Locus tag  DAQB-147D11.1
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.183 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIPI15735003 
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006950response to stressIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AIFM1AIF | MGC111425 | PDCD8apoptosis-inducing factor, mitochondrion-associated, 1-HPRD,BioGRID11533664 
APAF1CED4 | DKFZp781B1145apoptotic peptidase activating factor 1-HPRD10934467 
APEX1APE | APE-1 | APE1 | APEN | APEX | APX | HAP1 | REF-1 | REF1APEX nuclease (multifunctional DNA repair enzyme) 1-HPRD11133992 
APOBFLDBapolipoprotein B (including Ag(x) antigen)-HPRD9252351 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptorAffinity Capture-WesternBioGRID1540595 
BAG1RAP46BCL2-associated athanogeneReconstituted ComplexBioGRID14517289 
BAG2BAG-2 | KIAA0576 | MGC149462 | dJ417I1.2BCL2-associated athanogene 2-HPRD9873016 
BAG3BAG-3 | BIS | CAIR-1 | MGC104307BCL2-associated athanogene 3-HPRD,BioGRID9873016|10980614 
BAG4BAG-4 | SODDBCL2-associated athanogene 4-HPRD,BioGRID11527400 
BAT3BAG-6 | BAG6 | D6S52E | G3HLA-B associated transcript 3in vivoBioGRID11230127 
BCL2Bcl-2B-cell CLL/lymphoma 2-HPRD,BioGRID10354271 
CDK9C-2k | CDC2L4 | CTK1 | PITALRE | TAKcyclin-dependent kinase 9-HPRD,BioGRID10617616 
CUL4A-cullin 4AAffinity Capture-MSBioGRID12481031 
DNAJB1HSPF1 | Hdj1 | Hsp40 | Sis1DnaJ (Hsp40) homolog, subfamily B, member 1-HPRD10593983 
DNAJB11ABBP-2 | ABBP2 | DJ9 | EDJ | ERdj3 | ERj3 | HEDJ | PRO1080 | UNQ537 | hDj9DnaJ (Hsp40) homolog, subfamily B, member 11-HPRD11584023 
EIF2AK1HCR | HRI | KIAA1369eukaryotic translation initiation factor 2-alpha kinase 1in vivoBioGRID12149123 
EIF2AK2EIF2AK1 | MGC126524 | PKR | PRKReukaryotic translation initiation factor 2-alpha kinase 2-HPRD12397061 
FANCCFA3 | FAC | FACC | FLJ14675Fanconi anemia, complementation group CAffinity Capture-Western
Two-hybrid		BioGRID12397061 |14499622 
-HPRD11500375 |12397061 
GRIN1NMDA1 | NMDAR1 | NR1glutamate receptor, ionotropic, N-methyl D-aspartate 1-HPRD10862698 
HSF1HSTF1heat shock transcription factor 1-HPRD,BioGRID9699716 
HSF2MGC117376 | MGC156196 | MGC75048heat shock transcription factor 2HSF2 interacts with hsp70i promoter.BIND15662014 
HSP90AA1FLJ31884 | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP2heat shock protein 90kDa alpha (cytosolic), class A member 1Reconstituted ComplexBioGRID12093808 
HSPBP1-hsp70-interacting protein-HPRD9830037 
IKBKGAMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMOinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gammaReconstituted ComplexBioGRID11877453 
KRT7CK7 | K2C7 | K7 | MGC129731 | MGC3625 | SCLkeratin 7-HPRD11888936 
MAP3K5ASK1 | MAPKKK5 | MEKK5mitogen-activated protein kinase kinase kinase 5-HPRD,BioGRID12391142 
MAP3K7IP2FLJ21885 | KIAA0733 | TAB2mitogen-activated protein kinase kinase kinase 7 interacting protein 2-HPRD14743216 
MSR1CD204 | SCARA1 | SR-A | phSR1 | phSR2macrophage scavenger receptor 1-HPRD,BioGRID11785981 
NQO1DHQU | DIA4 | DTD | NMOR1 | NMORI | QR1NAD(P)H dehydrogenase, quinone 1-HPRD11821413 
NR3C1GCCR | GCR | GR | GRLnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)-HPRD,BioGRID12093808 
PEX5FLJ50634 | FLJ50721 | FLJ51948 | PTS1-BP | PTS1R | PXR1peroxisomal biogenesis factor 5-HPRD11415446 
PPP1R15AGADD34protein phosphatase 1, regulatory (inhibitor) subunit 15A-HPRD12724406 
PTMAMGC104802 | TMSAprothymosin, alpha-HPRD11310559 
RBX1BA554C12.1 | MGC13357 | MGC1481 | RNF75 | ROC1ring-box 1Affinity Capture-MSBioGRID12481031 
RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog gene family, member AAffinity Capture-WesternBioGRID12490434 
SLC5A1D22S675 | NAGT | SGLT1solute carrier family 5 (sodium/glucose cotransporter), member 1-HPRD,BioGRID12082088 
SOX9CMD1 | CMPD1 | SRA1SRY (sex determining region Y)-box 9-HPRD,BioGRID11356186 
ST13AAG2 | FAM10A1 | FAM10A4 | FLJ27260 | HIP | HOP | HSPABP | HSPABP1 | MGC129952 | P48 | PRO0786 | SNC6suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)in vivoBioGRID8887650 
STIP1HOP | IEF-SSP-3521 | P60 | STI1 | STI1Lstress-induced-phosphoprotein 1-HPRD12161444 
STUB1CHIP | HSPABP2 | NY-CO-7 | SDCCAG7 | UBOX1STIP1 homology and U-box containing protein 1-HPRD,BioGRID10330192 
TCERG1CA150 | MGC133200 | TAF2Stranscription elongation regulator 1-HPRD15456888 
TOMM70AFLJ90470translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)-HPRD12526792 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD7811761 
TRIM24PTC6 | RNF82 | TF1A | TIF1 | TIF1A | TIF1ALPHA | hTIF1tripartite motif-containing 24-HPRD12677068 
TTC1FLJ46404 | TPR1tetratricopeptide repeat domain 1-HPRD14503850 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 8965All SZGR genes in this pathway
KEGG_PRION_DISEASES 3528All SZGR genes in this pathway
BIOCARTA_TID_PATHWAY 1915All SZGR genes in this pathway
BIOCARTA_P53HYPOXIA_PATHWAY 2321All SZGR genes in this pathway
BIOCARTA_PPARA_PATHWAY 5843All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN 6235All SZGR genes in this pathway
NOJIMA_SFRP2_TARGETS_UP 3123All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP 13680All SZGR genes in this pathway
HOEBEKE_LYMPHOID_STEM_CELL_DN 8659All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP 431237All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_DN 3119All SZGR genes in this pathway
VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN 1610All SZGR genes in this pathway
MAHADEVAN_RESPONSE_TO_MP470_DN 1911All SZGR genes in this pathway
DAUER_STAT3_TARGETS_DN 5034All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
WOOD_EBV_EBNA1_TARGETS_UP 11071All SZGR genes in this pathway
STANHILL_HRAS_TRANSFROMATION_UP 85All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
FUJIWARA_PARK2_HEPATOCYTE_PROLIFERATION_UP 108All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP 11679All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
DEN_INTERACT_WITH_LCA5 2621All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_DN 3822All SZGR genes in this pathway
UEDA_CENTRAL_CLOCK 8862All SZGR genes in this pathway
LAMB_CCND1_TARGETS 1914All SZGR genes in this pathway
MENSSEN_MYC_TARGETS 5335All SZGR genes in this pathway
BROCKE_APOPTOSIS_REVERSED_BY_IL6 14498All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
GENTILE_UV_LOW_DOSE_UP 2719All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
CUI_TCF21_TARGETS_DN 3123All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_8HR_UP 10573All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
DELLA_RESPONSE_TO_TSA_AND_BUTYRATE 2117All SZGR genes in this pathway
SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER 4930All SZGR genes in this pathway
MOREIRA_RESPONSE_TO_TSA_UP 2823All SZGR genes in this pathway
ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP 3021All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C0 10772All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C1 2414All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_DN 10567All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_DN 7844All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN 4831All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN 2413All SZGR genes in this pathway
LIN_NPAS4_TARGETS_UP 163100All SZGR genes in this pathway
CADWELL_ATG16L1_TARGETS_DN 7043All SZGR genes in this pathway
KRISHNAN_FURIN_TARGETS_UP 126All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP 14985All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_UP 4025All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_UP 129All SZGR genes in this pathway
TIAN_TNF_SIGNALING_NOT_VIA_NFKB 2216All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5 3022All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
DALESSIO_TSA_RESPONSE 2916All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_2HR_DN 5535All SZGR genes in this pathway


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