Gene Page: CTNNBIP1

Summary
GeneID  56998
Symbol  CTNNBIP1
Synonyms  ICAT|MGC15093
Description  catenin, beta interacting protein 1
See related  HGNC:16913|MIM:607758|Ensembl:ENSG00000178585|HPRD:09677|
Locus tag  -
Gene type  protein-coding
Map location  1p36.22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0069 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008013beta-catenin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0006355regulation of transcription, DNA-dependentTAS10898789 
GO:0009952anterior/posterior pattern formationIEA-
GO:0007165signal transductionTAS10898789 
GO:0008283cell proliferationTAS10898789 
GO:0007275multicellular organismal developmentTAS10898789 
GO:0030178negative regulation of Wnt receptor signaling pathwayIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BEND5C1orf165 | FLJ11588BEN domain containing 5Two-hybridBioGRID16189514 
CASP4ICE(rel)II | ICEREL-II | ICH-2 | Mih1/TX | TXcaspase 4, apoptosis-related cysteine peptidaseAffinity Capture-MSBioGRID17353931 
CPVLHVLP | MGC10029carboxypeptidase, vitellogenic-likeAffinity Capture-MSBioGRID17353931 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDa-HPRD,BioGRID10898789 
CTSAGLB2 | GSL | NGBE | PPCA | PPGBcathepsin AAffinity Capture-MSBioGRID17353931 
GLB1EBP | ELNR1galactosidase, beta 1Affinity Capture-MSBioGRID17353931 
GOT2FLJ40994 | KAT4 | KATIV | mitAATglutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)Affinity Capture-MSBioGRID17353931 
JUPARVD12 | CTNNG | DP3 | DPIII | PDGB | PKGBjunction plakoglobinAffinity Capture-MS
Two-hybrid
BioGRID16189514 |17353931 
NACAP1FKSG17nascent-polypeptide-associated complex alpha polypeptide pseudogene 1Affinity Capture-MSBioGRID17353931 
PNMA2KIAA0883 | MA2 | MM2 | RGAG2paraneoplastic antigen MA2Affinity Capture-MSBioGRID17353931 
PPP2R1AMGC786 | PR65Aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoformAffinity Capture-MSBioGRID17353931 
RPA3REPA3replication protein A3, 14kDaAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_WNT_SIGNALING_PATHWAY 151112All SZGR genes in this pathway
WNT_SIGNALING 8971All SZGR genes in this pathway
PID_BETA_CATENIN_NUC_PATHWAY 8060All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
WANG_RESPONSE_TO_BEXAROTENE_UP 3417All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
WINNEPENNINCKX_MELANOMA_METASTASIS_DN 4626All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-10511517m8hsa-miR-10aUACCCUGUAGAUCCGAAUUUGUG
hsa-miR-10bUACCCUGUAGAACCGAAUUUGU
miR-1454074141A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-192/215362368m8hsa-miR-192CUGACCUAUGAAUUGACAGCC
hsa-miR-215AUGACCUAUGAAUUGACAGAC
miR-233793861A,m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-25/32/92/363/3675715771Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-265425481Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-29350356m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-3233793851Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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