Gene Page: SHOX2

Summary
GeneID  6474
Symbol  SHOX2
Synonyms  OG12|OG12X|OGI2X|SHOT
Description  short stature homeobox 2
See related  HGNC:10854|MIM:602504|Ensembl:ENSG00000168779|
Locus tag  -
Gene type  protein-coding
Map location  3q25-q26.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AC008622.10.920.80
TEAD20.890.68
TP530.880.76
TCF190.880.80
BTG10.870.82
CDCA70.870.80
CDK20.870.69
CDO10.870.72
PTBP10.860.72
KIF220.860.79
Top 10 negatively co-expressed genes
C5orf53-0.51-0.75
FBXO2-0.48-0.59
HLA-F-0.48-0.64
AIFM3-0.48-0.65
AF347015.27-0.47-0.75
AF347015.31-0.47-0.76
CA4-0.47-0.68
PTH1R-0.47-0.63
S100B-0.46-0.69
AF347015.33-0.46-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)9482898 
GO:0001501skeletal system developmentTAS9482898 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007507heart developmentTAS9482898 
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN 5036All SZGR genes in this pathway
NADERI_BREAST_CANCER_PROGNOSIS_DN 1813All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
COWLING_MYCN_TARGETS 4327All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_UP 11866All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
HAN_JNK_SINGALING_UP 3521All SZGR genes in this pathway
BURTON_ADIPOGENESIS_11 5740All SZGR genes in this pathway
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP 2617All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP 7747All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP 8750All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_CLASSICAL 162122All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p8618671Ahsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-18142714331Ahsa-miR-18aUAAGGUGCAUCUAGUGCAGAUA
hsa-miR-18bUAAGGUGCAUCUAGUGCAGUUA
miR-2149209261Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-3307777841A,m8hsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
miR-375148914961A,m8hsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
miR-494162916351Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
miR-9619551961m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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