Gene Page: TAT

Summary
GeneID  6898
Symbol  TAT
Synonyms  -
Description  tyrosine aminotransferase
See related  HGNC:11573|MIM:276600|Ensembl:ENSG00000198650|HPRD:11776|
Locus tag  -
Gene type  protein-coding
Map location  16q22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HAUS60.920.92
RYK0.920.89
SP30.910.90
PRPF38A0.910.86
EPB41L50.910.90
CTNND10.910.90
LSM14A0.900.91
SMAD40.900.90
NUP2050.900.88
VEZF10.900.93
Top 10 negatively co-expressed genes
MT-CO2-0.60-0.76
AF347015.31-0.60-0.75
C5orf53-0.59-0.65
IFI27-0.59-0.75
FXYD1-0.59-0.74
AF347015.27-0.59-0.72
AF347015.33-0.57-0.70
CXCL14-0.57-0.74
AF347015.8-0.57-0.73
CA4-0.57-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004838tyrosine transaminase activityIEAglutamate (GO term level: 6)-
GO:0004838tyrosine transaminase activityNASglutamate (GO term level: 6)1973834 
GO:00168471-aminocyclopropane-1-carboxylate synthase activityIEA-
GO:0030170pyridoxal phosphate bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009074aromatic amino acid family catabolic processIEA-
GO:0006519cellular amino acid and derivative metabolic processIEA-
GO:0009058biosynthetic processIEA-
GO:0006559L-phenylalanine catabolic processNAS-
GO:0006572tyrosine catabolic processNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005739mitochondrionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRNGEP | GP88 | PCDGF | PEPI | PGRNgranulinAffinity Capture-Western
Reconstituted Complex		BioGRID12588988 
MDFICHICMyoD family inhibitor domain containingAffinity Capture-Western
Two-hybrid		BioGRID12944466 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 3424All SZGR genes in this pathway
KEGG_TYROSINE_METABOLISM 4230All SZGR genes in this pathway
KEGG_PHENYLALANINE_METABOLISM 1812All SZGR genes in this pathway
PID_HNF3B_PATHWAY 4537All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN 1913All SZGR genes in this pathway
XU_AKT1_TARGETS_6HR 2718All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
SU_LIVER 5532All SZGR genes in this pathway
LEIN_MEDULLA_MARKERS 8148All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 19693All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_A_UP 8452All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
LABBE_WNT3A_TARGETS_UP 11271All SZGR genes in this pathway
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP 11170All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_DN 10971All SZGR genes in this pathway
GUO_TARGETS_OF_IRS1_AND_IRS2 9867All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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