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Gene Page: YWHAZ

Summary

GeneID

7534

Symbol

YWHAZ

Synonyms

KCIP-1|MGC111427|MGC126532|MGC138156

Description

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Locus tag

Gene type

protein-coding

Map location

8q23.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Association

A combined odds ratio method (Sun et al. 2008), association studies

Link to SZGene

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 11.6823

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008134

transcription factor binding

IPI

16114898

GO:0019904

protein domain specific binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007165

signal transduction

TAS

16130169

GO:0006916

anti-apoptosis

TAS

16130169

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

TAS

16130169

GO:0042470

melanosome

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AANAT	AA-NAT \| SNAT	arylalkylamine N-acetyltransferase	-	HPRD,BioGRID	11336675
AANAT	AA-NAT \| SNAT	arylalkylamine N-acetyltransferase	AANAT interacts with 14-3-3-zeta isoform. This interaction was modeled on a demonstrated interaction between sheep AANAT and human 14-3-3-zeta.	BIND	8024705 \|11336675 \|11427721
ADAM22	MDC2 \| MGC149832	ADAM metallopeptidase domain 22	-	HPRD	12589811
ADRA2A	ADRA2 \| ADRA2R \| ADRAR \| ALPHA2AAR \| ZNF32	adrenergic, alpha-2A-, receptor	-	HPRD	10224112
ADRA2B	ADRA2L1 \| ADRA2RL1 \| ADRARL1 \| ALPHA2BAR	adrenergic, alpha-2B-, receptor	-	HPRD	10224112
ADRA2C	ADRA2L2 \| ADRA2RL2 \| ADRARL2 \| ALPHA2CAR	adrenergic, alpha-2C-, receptor	-	HPRD	10224112
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	-	HPRD,BioGRID	11956222
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2.	BIND	11956222
ARHGEF2	DKFZp547L106 \| DKFZp547P1516 \| GEF \| GEF-H1 \| GEFH1 \| KIAA0651 \| LFP40 \| P40	rho/rac guanine nucleotide exchange factor (GEF) 2	-	HPRD	14970201
BAD	BBC2 \| BCL2L8	BCL2-associated agonist of cell death	-	HPRD,BioGRID	11410287
BCAR1	CAS \| CAS1 \| CASS1 \| CRKAS \| P130Cas	breast cancer anti-estrogen resistance 1	-	HPRD,BioGRID	10026197
BCR	ALL \| BCR-ABL1 \| BCR1 \| CML \| D22S11 \| D22S662 \| FLJ16453 \| PHL	breakpoint cluster region	-	HPRD	7939633
BRAF	B-RAF1 \| BRAF1 \| FLJ95109 \| MGC126806 \| MGC138284 \| RAFB1	v-raf murine sarcoma viral oncogene homolog B1	Affinity Capture-MS	BioGRID	17353931
BRAF	B-RAF1 \| BRAF1 \| FLJ95109 \| MGC126806 \| MGC138284 \| RAFB1	v-raf murine sarcoma viral oncogene homolog B1	-	HPRD	8668348
BSPRY	FLJ20150	B-box and SPRY domain containing	-	HPRD	12615066
C22orf9	-	chromosome 22 open reading frame 9	Affinity Capture-MS	BioGRID	17353931
CBL	C-CBL \| CBL2 \| RNF55	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Two-hybrid	BioGRID	9367879
CBL	C-CBL \| CBL2 \| RNF55		c-Cbl interacts with 14-3-3-zeta.	BIND	9367879
CDC25A	CDC25A2	cell division cycle 25 homolog A (S. pombe)	-	HPRD,BioGRID	11912208
CDC25B	-	cell division cycle 25 homolog B (S. pombe)	-	HPRD,BioGRID	10713667
CDC25B	-	cell division cycle 25 homolog B (S. pombe)	14-3-3-zeta interacts with phosphorylated CDC25B.	BIND	15629715
CDC25C	CDC25	cell division cycle 25 homolog C (S. pombe)	-	HPRD,BioGRID	10864927
CLIC4	CLIC4L \| DKFZp566G223 \| FLJ38640 \| H1 \| MTCLIC \| huH1 \| p64H1	chloride intracellular channel 4	-	HPRD	11563969
CSF2RB	CD131 \| CDw131 \| IL3RB \| IL5RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	-	HPRD,BioGRID	8278375 \|10477722
DFFA	DFF-45 \| DFF1 \| ICAD	DNA fragmentation factor, 45kDa, alpha polypeptide	Affinity Capture-MS	BioGRID	17353931
EDC3	FLJ21128 \| FLJ31777 \| LSM16 \| YJDC \| YJEFN2	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	Affinity Capture-MS	BioGRID	17353931
EGFR	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	EGFR interacts with 14-3-3-zeta.	BIND	15225635
EPB41L3	4.1B \| DAL-1 \| DAL1 \| FLJ37633 \| KIAA0987	erythrocyte membrane protein band 4.1-like 3	Affinity Capture-MS	BioGRID	17353931
FOXO1	FKH1 \| FKHR \| FOXO1A	forkhead box O1	-	HPRD,BioGRID	11237865
FOXO3	AF6q21 \| DKFZp781A0677 \| FKHRL1 \| FKHRL1P2 \| FOXO2 \| FOXO3A \| MGC12739 \| MGC31925	forkhead box O3	-	HPRD,BioGRID	10102273
GP1BA	BSS \| CD42B \| CD42b-alpha \| GP1B \| MGC34595	glycoprotein Ib (platelet), alpha polypeptide	-	HPRD,BioGRID	8631758 \|9454760 \|10627461\|9454760
GP1BB	CD42c	glycoprotein Ib (platelet), beta polypeptide	-	HPRD	8034572 \|10627461
GP1BB	CD42c	glycoprotein Ib (platelet), beta polypeptide	in vitro in vivo Two-hybrid	BioGRID	8034572 \|9454760 \|10627461
HDAC4	HA6116 \| HD4 \| HDAC-A \| HDACA \| KIAA0288	histone deacetylase 4	Reconstituted Complex	BioGRID	11504882
HDAC4	HA6116 \| HD4 \| HDAC-A \| HDACA \| KIAA0288	histone deacetylase 4	-	HPRD	11486037
HMGN1	FLJ27265 \| FLJ31471 \| HMG14 \| MGC104230 \| MGC117425	high-mobility group nucleosome binding domain 1	-	HPRD,BioGRID	12215538
HNRNPL	FLJ35509 \| HNRPL \| P/OKcl.14 \| hnRNP-L	heterogeneous nuclear ribonucleoprotein L	Affinity Capture-MS	BioGRID	17353931
IGF1R	CD221 \| IGFIR \| JTK13 \| MGC142170 \| MGC142172 \| MGC18216	insulin-like growth factor 1 receptor	-	HPRD	9581554
IGF1R	CD221 \| IGFIR \| JTK13 \| MGC142170 \| MGC142172 \| MGC18216	insulin-like growth factor 1 receptor	IGFIR interacts with 14-3-3-zeta isoform.	BIND	9581554
IL9R	CD129	interleukin 9 receptor	-	HPRD,BioGRID	10642536
INPP5A	5PTASE \| DKFZp434A1721 \| MGC116947 \| MGC116949	inositol polyphosphate-5-phosphatase, 40kDa	-	HPRD,BioGRID	9398266
IRS1	HIRS-1	insulin receptor substrate 1	-	HPRD,BioGRID	9312143
IRS2	-	insulin receptor substrate 2	-	HPRD,BioGRID	9312143
KIAA1377	-	KIAA1377	Two-hybrid	BioGRID	16169070
KIF1C	KIAA0706 \| LTXS1	kinesin family member 1C	-	HPRD	10559254
KIF5B	KINH \| KNS \| KNS1 \| UKHC	kinesin family member 5B	Affinity Capture-MS	BioGRID	17353931
KLC1	KLC \| KNS2 \| KNS2A \| MGC15245	kinesin light chain 1	Affinity Capture-MS	BioGRID	17353931
KLC4	KNSL8 \| MGC111777 \| bA387M24.3	kinesin light chain 4	Affinity Capture-MS	BioGRID	17353931
KRT18	CYK18 \| K18	keratin 18	-	HPRD	9524113 \|11917136
LARP1	KIAA0731 \| LARP \| MGC19556	La ribonucleoprotein domain family, member 1	Affinity Capture-MS	BioGRID	17353931
LIMK1	LIMK	LIM domain kinase 1	-	HPRD,BioGRID	12323073
LYST	CHS \| CHS1	lysosomal trafficking regulator	Reconstituted Complex	BioGRID	11984006
MAP3K2	MEKK2 \| MEKK2B	mitogen-activated protein kinase kinase kinase 2	-	HPRD	9452471
MAP3K3	MAPKKK3 \| MEKK3	mitogen-activated protein kinase kinase kinase 3	-	HPRD	9452471
MAP3K5	ASK1 \| MAPKKK5 \| MEKK5	mitogen-activated protein kinase kinase kinase 5	-	HPRD,BioGRID	10411906\|11336675
MAPKAPK2	MK2	mitogen-activated protein kinase-activated protein kinase 2	MAPKAPK2 interacts with and phosphorylates 14-3-3-zeta.	BIND	12861023
MAPT	DDPAC \| FLJ31424 \| FTDP-17 \| MAPTL \| MGC138549 \| MSTD \| MTBT1 \| MTBT2 \| PPND \| TAU	microtubule-associated protein tau	Tau interacts with 14-3-3-zeta.	BIND	12176984
MAPT		microtubule-associated protein tau	-	HPRD,BioGRID	10840038
MLF1	-	myeloid leukemia factor 1	-	HPRD	12176995
NADK	FLJ13052 \| FLJ37724 \| dJ283E3.1	NAD kinase	Affinity Capture-MS	BioGRID	17353931
NCKAP1	FLJ11291 \| HEM2 \| KIAA0587 \| MGC8981 \| NAP1 \| NAP125	NCK-associated protein 1	Affinity Capture-MS	BioGRID	17353931
NFATC2	KIAA0611 \| NFAT1 \| NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	-	HPRD,BioGRID	10611249
NFATC4	NF-ATc4 \| NFAT3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	-	HPRD,BioGRID	10611249
NOLC1	KIAA0035 \| NOPP130 \| NOPP140 \| NS5ATP13 \| P130	nucleolar and coiled-body phosphoprotein 1	Affinity Capture-MS	BioGRID	17353931
PABPC4	APP-1 \| APP1 \| FLJ43938 \| PABP4 \| iPABP	poly(A) binding protein, cytoplasmic 4 (inducible form)	Affinity Capture-MS	BioGRID	17353931
PAK4	-	p21 protein (Cdc42/Rac)-activated kinase 4	Affinity Capture-MS	BioGRID	17353931
PCTK1	FLJ16665 \| PCTAIRE \| PCTAIRE1 \| PCTGAIRE	PCTAIRE protein kinase 1	-	HPRD,BioGRID	9197417
PDC	MEKA \| PHD \| PhLOP \| PhLP	phosducin	-	HPRD	11287646 \|11331285
PFKFB2	DKFZp781D2217 \| MGC138308 \| MGC138310 \| PFK-2/FBPase-2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	-	HPRD	12853467
PRKCA	AAG6 \| MGC129900 \| MGC129901 \| PKC-alpha \| PKCA \| PRKACA	protein kinase C, alpha	-	HPRD,BioGRID	11950841
PRKCD	MAY1 \| MGC49908 \| PKCD \| nPKC-delta	protein kinase C, delta	Affinity Capture-Western	BioGRID	11950841
PRKCE	MGC125656 \| MGC125657 \| PKCE \| nPKC-epsilon	protein kinase C, epsilon	Affinity Capture-Western	BioGRID	11950841
PRKCI	DXS1179E \| MGC26534 \| PKCI \| nPKC-iota	protein kinase C, iota	Reconstituted Complex	BioGRID	12893243
PRKCZ	PKC-ZETA \| PKC2	protein kinase C, zeta	Biochemical Activity Reconstituted Complex	BioGRID	10620507 \|12893243
PRKD1	PKC-MU \| PKCM \| PKD \| PRKCM	protein kinase D1	Reconstituted Complex	BioGRID	12893243
PTPN13	DKFZp686J1497 \| FAP-1 \| PNP1 \| PTP-BAS \| PTP-BL \| PTP1E \| PTPL1 \| PTPLE	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	-	HPRD	9305890
RAF1	CRAF \| NS5 \| Raf-1 \| c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1	Raf-1 interacts with 14-3-3 zeta. This interaction was modelled on a demonstrated interaction between human Raf-1 and murine 14-3-3-zeta.	BIND	7559537
			Affinity Capture-Western Reconstituted Complex	BioGRID	7628630 \|9261098 \|10620507 \|10887173
			-	HPRD	7628630 \|7939632
RAI14	DKFZp564G013 \| KIAA1334 \| NORPEG \| RAI13	retinoic acid induced 14	Affinity Capture-MS	BioGRID	17353931
RALGPS2	FLJ10244 \| FLJ25604 \| KIAA0351 \| dJ595C2.1	Ral GEF with PH domain and SH3 binding motif 2	Affinity Capture-MS	BioGRID	17353931
REM1	GD:REM \| GES \| MGC48669 \| REM	RAS (RAD and GEM)-like GTP-binding 1	-	HPRD,BioGRID	10441394
RGS3	C2PA \| FLJ20370 \| FLJ31516 \| FLJ90496 \| PDZ-RGS3 \| RGP3	regulator of G-protein signaling 3	-	HPRD,BioGRID	11985497
RIN1	-	Ras and Rab interactor 1	-	HPRD	9144171
RPL31	MGC88191	ribosomal protein L31	Affinity Capture-MS	BioGRID	17353931
RRAD	RAD \| RAD1 \| REM3	Ras-related associated with diabetes	Affinity Capture-Western	BioGRID	10441394
SAMD4B	FLJ10211 \| MGC99832 \| SMGB	sterile alpha motif domain containing 4B	Affinity Capture-MS	BioGRID	17353931
SF3B1	PRP10 \| PRPF10 \| SAP155 \| SF3b155	splicing factor 3b, subunit 1, 155kDa	Affinity Capture-MS	BioGRID	17353931
SFRS10	DKFZp686F18120 \| Htra2-beta \| SRFS10 \| TRA2-BETA \| TRA2B \| TRAN2B	splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)	Affinity Capture-MS	BioGRID	17353931
SSH1	FLJ38102 \| KIAA1298 \| SSH-1	slingshot homolog 1 (Drosophila)	SSH-1S interacts with 14-3-3-zeta.	BIND	15660133
SSH1	FLJ38102 \| KIAA1298 \| SSH-1	slingshot homolog 1 (Drosophila)	SSH-1L interacts with 14-3-3-zeta.	BIND	15660133
SSH2	KIAA1725 \| MGC78588 \| SSH-2	slingshot homolog 2 (Drosophila)	SSH-2S interacts with 14-3-3-zeta.	BIND	15660133
SSH3	FLJ10928 \| FLJ20515 \| SSH-3	slingshot homolog 3 (Drosophila)	SSH-3S interacts with 14-3-3-zeta.	BIND	15660133
SYN2	SYNII \| SYNIIa \| SYNIIb	synapsin II	Two-hybrid	BioGRID	10358015
TERT	EST2 \| TCS1 \| TP2 \| TRT \| hEST2	telomerase reverse transcriptase	Two-hybrid	BioGRID	10835362
TH	TYH	tyrosine hydroxylase	-	HPRD	11359875
TJP2	MGC26306 \| X104 \| ZO-2 \| ZO2	tight junction protein 2 (zona occludens 2)	Affinity Capture-MS	BioGRID	17353931
TNFAIP3	A20 \| MGC104522 \| MGC138687 \| MGC138688 \| OTUD7C \| TNFA1P2	tumor necrosis factor, alpha-induced protein 3	-	HPRD,BioGRID	9299557
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	9620776
TPH1	MGC119994 \| TPH \| TPRH	tryptophan hydroxylase 1	-	HPRD,BioGRID	8101440
TSC1	KIAA0243 \| LAM \| MGC86987 \| TSC	tuberous sclerosis 1	-	HPRD,BioGRID	12176984
TSC2	FLJ43106 \| LAM \| TSC4	tuberous sclerosis 2	-	HPRD	12176984 \|12438239 \|12468542
			-	HPRD,BioGRID	12176984
			Tumor suppressor protein tuberin interacts with 14-3-3-zeta isoform.	BIND	11533041 \|12176984
UCP2	BMIQ4 \| SLC25A8 \| UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	UCP2 interacts with 14.3.3-zeta.	BIND	10785390
UCP2	BMIQ4 \| SLC25A8 \| UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	-	HPRD,BioGRID	10785390
UCP3	SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	UCP3 interacts with 14.3.3-zeta.	BIND	10785390
UCP3	SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	-	HPRD,BioGRID	10785390
USP8	FLJ34456 \| HumORF8 \| KIAA0055 \| MGC129718 \| UBPY	ubiquitin specific peptidase 8	Affinity Capture-MS	BioGRID	17353931
VIM	FLJ36605	vimentin	-	HPRD,BioGRID	10887173
XRCC6	CTC75 \| CTCBF \| G22P1 \| KU70 \| ML8 \| TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	Two-hybrid	BioGRID	16169070
YWHAZ	KCIP-1 \| MGC111427 \| MGC126532 \| MGC138156	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	Affinity Capture-Western Reconstituted Complex	BioGRID	10887173
			-	HPRD	11336675
			14-3-3zeta homodimerizes.	BIND	12861023

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_CELL_CYCLE	128	84	All SZGR genes in this pathway
KEGG_OOCYTE_MEIOSIS	114	79	All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	126	103	All SZGR genes in this pathway
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION	59	36	All SZGR genes in this pathway
BIOCARTA_CHREBP2_PATHWAY	42	35	All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	67	54	All SZGR genes in this pathway
SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	51	41	All SZGR genes in this pathway
ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY	37	29	All SZGR genes in this pathway
PID_GMCSF_PATHWAY	37	31	All SZGR genes in this pathway
PID_ATR_PATHWAY	39	25	All SZGR genes in this pathway
PID_LKB1_PATHWAY	47	37	All SZGR genes in this pathway
PID_NFAT_3PATHWAY	54	47	All SZGR genes in this pathway
PID_MTOR_4PATHWAY	69	55	All SZGR genes in this pathway
PID_IGF1_PATHWAY	30	23	All SZGR genes in this pathway
PID_FOXO_PATHWAY	49	43	All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY	105	78	All SZGR genes in this pathway
PID_IL3_PATHWAY	27	19	All SZGR genes in this pathway
PID_PDGFRB_PATHWAY	129	103	All SZGR genes in this pathway
PID_P38_MK2_PATHWAY	21	19	All SZGR genes in this pathway
PID_BETA_CATENIN_NUC_PATHWAY	80	60	All SZGR genes in this pathway
PID_A6B1_A6B4_INTEGRIN_PATHWAY	46	35	All SZGR genes in this pathway
PID_INSULIN_GLUCOSE_PATHWAY	26	24	All SZGR genes in this pathway
PID_PI3KCI_AKT_PATHWAY	35	30	All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY	36	31	All SZGR genes in this pathway
PID_INTEGRIN_A4B1_PATHWAY	33	24	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA	284	128	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA	330	155	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS	107	86	All SZGR genes in this pathway
REACTOME_IL_3_5_AND_GM_CSF_SIGNALING	43	34	All SZGR genes in this pathway
REACTOME_RAP1_SIGNALLING	17	12	All SZGR genes in this pathway
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS	84	50	All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP	17	9	All SZGR genes in this pathway
REACTOME_HEMOSTASIS	466	331	All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM	539	350	All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	270	204	All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	208	138	All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP	783	507	All SZGR genes in this pathway
FRASOR_TAMOXIFEN_RESPONSE_UP	51	36	All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP	423	283	All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP	1382	904	All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP	305	185	All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP	457	269	All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP	501	327	All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	633	376	All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	722	443	All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP	177	113	All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP	530	342	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	770	415	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP	170	114	All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP	117	85	All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_DN	45	29	All SZGR genes in this pathway
LI_LUNG_CANCER	41	30	All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B	392	251	All SZGR genes in this pathway
PATIL_LIVER_CANCER	747	453	All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP	358	245	All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	584	395	All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP	769	437	All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP	1037	673	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	514	330	All SZGR genes in this pathway
SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN	45	33	All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN	206	136	All SZGR genes in this pathway
DEN_INTERACT_WITH_LCA5	26	21	All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON	132	82	All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	151	100	All SZGR genes in this pathway
WANG_TARGETS_OF_MLL_CBP_FUSION_UP	44	26	All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN	163	115	All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN	141	99	All SZGR genes in this pathway
LU_AGING_BRAIN_DN	153	120	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_DN	58	43	All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP	123	75	All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL	311	205	All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN	434	302	All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	264	168	All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE	77	50	All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM	66	47	All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST	132	93	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED	1229	713	All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	315	197	All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP	648	398	All SZGR genes in this pathway
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	463	262	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN	210	128	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN	366	257	All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES	389	245	All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_UP	47	38	All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP	605	377	All SZGR genes in this pathway
GUTIERREZ_MULTIPLE_MYELOMA_UP	35	24	All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN	553	343	All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	824	528	All SZGR genes in this pathway
IKEDA_MIR1_TARGETS_UP	53	39	All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP	116	87	All SZGR genes in this pathway
GUILLAUMOND_KLF10_TARGETS_UP	51	39	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	590	597	1A,m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-149	172	178	m8	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-155	1353	1360	1A,m8	hsa-miR-155	UUAAUGCUAAUCGUGAUAGGGG
miR-193	296	302	m8	hsa-miR-193a	AACUGGCCUACAAAGUCCCAG
miR-193	296	302	m8	hsa-miR-193b	AACUGGCCCUCAAAGUCCCGCUUU
miR-214	613	619	m8	hsa-miR-214^brain	ACAGCAGGCACAGACAGGCAG
miR-30-5p	85	91	m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-328	294	300	m8	hsa-miR-328^brain	CUGGCCCUCUCUGCCCUUCCGU
miR-34b	334	341	1A,m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-433-3p	916	922	1A	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-451	582	588	m8	hsa-miR-451^brain	AAACCGUUACCAUUACUGAGUUU
miR-544	577	583	1A	hsa-miR-544	AUUCUGCAUUUUUAGCAAGU
miR-93.hd/291-3p/294/295/302/372/373/520	426	433	1A,m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.