Gene Page: PITPNM1

Summary
GeneID  9600
Symbol  PITPNM1
Synonyms  DRES9|FLJ44997|NIR2|PITPNM|RDGB|RDGB1|RDGBA|RDGBA1|Rd9
Description  phosphatidylinositol transfer protein, membrane-associated 1
See related  HGNC:9003|MIM:608794|Ensembl:ENSG00000110697|HPRD:07497|
Locus tag  -
Gene type  protein-coding
Map location  11q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DUSP150.740.64
C6orf1080.680.52
PLCB20.640.42
HLA-DPB20.630.30
CCDC960.610.13
C14orf1790.610.54
SLC16A80.610.52
EXOC3L0.600.44
F120.600.49
DDC0.600.23
Top 10 negatively co-expressed genes
KCNJ3-0.39-0.47
CDH18-0.38-0.49
ANKRD56-0.38-0.43
OSBPL3-0.37-0.52
ELL2-0.37-0.48
SH3GL2-0.36-0.45
FBXW7-0.36-0.39
CAP2-0.36-0.45
C6orf142-0.35-0.46
SORL1-0.35-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0008526phosphatidylinositol transporter activityTAS9245688 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentTASBrain (GO term level: 7)9245688 
GO:0007602phototransductionTAS9680295 
GO:0006629lipid metabolic processNAS9680295 
GO:0015031protein transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005622intracellularIEA-
GO:0005624membrane fractionTAS9245688 
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0012511monolayer-surrounded lipid storage bodyIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDC2CDC28A | CDK1 | DKFZp686L20222 | MGC111195cell division cycle 2, G1 to S and G2 to MNir2 is phosphorylated by Cdk1.BIND15125835 
PLK1PLK | STPK13polo-like kinase 1 (Drosophila)Nir2 interacts with Plk1.BIND15125835 
PTK2BCADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTKPTK2B protein tyrosine kinase 2 beta-HPRD,BioGRID10022914 
RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog gene family, member ANir2 interacts with RhoA.BIND15125835 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM6 4632All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON 15893All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
VANLOO_SP3_TARGETS_DN 8947All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR 15288All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4911131191Ahsa-miR-491brainAGUGGGGAACCCUUCCAUGAGGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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