Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 476 literature records

Page :1 2 3 4 5 6 7 8 9 10
Entrez IDDescription
6091Dutt1/Robo1 is a classic tumor suppressor gene requiring inactivation of both alleles to elicit lung tumorigenesis in these mice.
3621Decreased expression of the candidate tumor suppressor gene ING1 is associated with advanced neuroblastomas
1474Cystatin m: a novel candidate tumor suppressor gene for breast cancer.
9368NHERF to be a candidate tumor suppressor gene in human breast carcinoma that may be interconnected to the SYK and MERLIN suppressors
51147"detected deletion of the ING4 locus in 10-20% of human breast cancer cell lines and primary breast tumors, supporting the possibility that ING4 might be a tumor suppressor gene"
23047"We mapped the complete BRCA2 deletion, which extends over at least 298 kb and showed that it does not affect APRIN/AS3, previously characterized as a tumor suppressor gene, but it comprises several loci corresponding to proven or putative transcripts of unknown functional significance."
51741Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.
23221High expression during neurogenesis but not mammogenesis of a murine homologue of the Deleted in Breast Cancer2/Rhobtb2 tumor suppressor.
5268Prognostic significance of the tumor suppressor gene maspin in non-small cell lung cancer.
1801Gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor OVCA1 is a component of the biosynthetic pathway of diphthamide on elongation factor 2.
7157Epigallocatechin-3-gallate increased expression of tumor suppressor protein p53 in brest cancer cells.
11337GABARAP mRNA expression and protein expression were significantly down-regulated in invasive ductal and invasive lobular carcinomas; GABARAP acts via a vesicle transport mechanism as a tumor suppressor in breast cancer.
55615"Thus, PRR5 may represent a potential candidate tumor suppressor gene in breast cancer"
55193The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer.
11186The tumor suppressor RASSF1A in human carcinogenesis: an update.
5268the human tumor suppressor maspin has a conformational switch in the G-helix
11315"DJ-1, a novel regulator of the tumor suppressor PTEN."
5728"DJ-1, a novel regulator of the tumor suppressor PTEN."
23513data establishs a potential link between the E-cadherin and hScrib tumor suppressors
57805Caspase-dependent processing of DBC-1 may act as a feed-forward mechanism to promote apoptosis and possibly also tumor suppression.
11186"Review summarizes current knowledge on genetic, epigenetic, and functional analysis of RASSF1A tumor suppressor gene and its homologues."
3659Functional role for IRF-1 in the growth suppression of breast cancer cells and strongly implicate IRF-1 as a tumor suppressor gene in breast cancer that act to control apoptosis.
5728The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN.
11186A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast.
11186Methylation of the tumor suppressor gene RASSF1A in human tumors.
27075NET-6 may represent a novel breast cancer suppressor gene.
9077Association between STAT3 and ARHI as well as the functional inhibition of STAT3 transcriptional activity by ARHI suggests a novel mechanism through which a putative tumor suppressor gene can inhibit STAT3 activity in breast and ovarian cancers.
7490The WT1 Wilms' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells.
1540The tumor suppressor familial cylindromatosis gene (CYLD) was found to be a direct target of BAF57 as determined by chromatin immunoprecipitation analysis. (CYLD)
23136Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma.
9077E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.
54971Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex.
4089Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway.
5325The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas.
57575"Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation."
5915RARbeta2 induces a number of tumor suppressor functions and metastasis suppressors
92304"Studies provide further evidence that HIN-1 possesses tumor suppressor functions, and that these activities may be mediated through the AKT signaling pathway."
135138"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
5071"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
11186[The RASSF1 (Ras association domain family protein 1) gene. Category: tumor suppressor gene].
672"BRCA1 affects lipogenesis through binding to P-ACCA, suggesting a new mechanism by which BRCA1 may exert a tumor suppressor function"
1474"The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin."
79791"FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex."
7157"BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis."
7832"BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis."
23136The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
149628IFIX alpha1 isoform functions as a tumor suppressor by repressing HDM2 function
4335Mnt functions as a tumor suppressor and reveal a critical and surprising role for Mnt in the regulation of T-cell development and in T-cell-dependent immune homeostasis.
4830These data imply that nm-23 may be tumor suppressor gene involved in neck squamous cell carcinomas but that it may not function as a tumor metastasis suppressor in high-stage laryngeal carcinoma.
10181Results suggest that LUCA-15 plays a central role in regulating cell fate consistent with its tumor suppressor activity.


')