Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB00477
Drug NameChlorpromazine
Target IDBE0000451
UniProt IDP28223
Regulation Typeantagonist
PubMed IDs10821438; 8593484
CitationsKusumi I, Takahashi Y, Suzuki K, Kameda K, Koyama T: Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain. J Neural Transm (Vienna). 2000;107(3):295-302.@@Yamada J, Sugimoto Y, Horisaka K: Serotonin2 (5-HT2) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) inhibits chlorpromazine- and haloperidol-induced hypothermia in mice. Biol Pharm Bull. 1995 Nov;18(11):1580-3.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationPhenothiazines
SMILESCN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
Pathways
PharmGKBPA448964
ChEMBLCHEMBL71