VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS10016573 | HBV | ENSG00000102468.11 | protein_coding | HTR2A | No | No | 3356 | P28223 |
TVIS44041305 | HTLV-1 | ENSG00000102468.11 | protein_coding | HTR2A | No | No | 3356 | P28223 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | HTR2A |
---|---|
DrugBank ID | DB00477 |
Drug Name | Chlorpromazine |
Target ID | BE0000451 |
UniProt ID | P28223 |
Regulation Type | antagonist |
PubMed IDs | 10821438; 8593484 |
Citations | Kusumi I, Takahashi Y, Suzuki K, Kameda K, Koyama T: Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain. J Neural Transm (Vienna). 2000;107(3):295-302.@@Yamada J, Sugimoto Y, Horisaka K: Serotonin2 (5-HT2) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) inhibits chlorpromazine- and haloperidol-induced hypothermia in mice. Biol Pharm Bull. 1995 Nov;18(11):1580-3. |
Groups | Approved; Investigational; Vet_approved |
Direct Classification | Phenothiazines |
SMILES | CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2 |
Pathways | |
PharmGKB | PA448964 |
ChEMBL | CHEMBL71 |