Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB01079
Drug NameTegaserod
Target IDBE0000451
UniProt IDP28223
Regulation Typeantagonist
PubMed IDs15466450
CitationsBeattie DT, Smith JA, Marquess D, Vickery RG, Armstrong SR, Pulido-Rios T, McCullough JL, Sandlund C, Richardson C, Mai N, Humphrey PP: The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. Br J Pharmacol. 2004 Nov;143(5):549-60. Epub 2004 Oct 4.
GroupsApproved; Investigational; Withdrawn
Direct ClassificationIndoles
SMILESCCCCCNC(=N)NN=CC1=CNC2=C1C=C(OC)C=C2
Pathways
PharmGKBPA130413154
ChEMBLCHEMBL76370