Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB00555
Drug NameLamotrigine
Target IDBE0000451
UniProt IDP28223
Regulation Typeinhibitor
PubMed IDs22306746
CitationsAbelaira HM, Reus GZ, Ribeiro KF, Zappellini G, Cipriano AL, Scaini G, Streck EL, Quevedo J: Lamotrigine treatment reverses depressive-like behavior and alters BDNF levels in the brains of maternally deprived adult rats. Pharmacol Biochem Behav. 2012 May;101(3):348-53. doi: 10.1016/j.pbb.2012.01.019. Epub 2012 Jan 27.
GroupsApproved; Investigational
Direct ClassificationDichlorobenzenes
SMILESNC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
Pathways
PharmGKBPA450164
ChEMBLCHEMBL741