Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB01623
Drug NameThiothixene
Target IDBE0000451
UniProt IDP28223
Regulation Typeantagonist
PubMed IDs10821438; 12629531
CitationsKusumi I, Takahashi Y, Suzuki K, Kameda K, Koyama T: Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain. J Neural Transm (Vienna). 2000;107(3):295-302.@@Kroeze WK, Hufeisen SJ, Popadak BA, Renock SM, Steinberg S, Ernsberger P, Jayathilake K, Meltzer HY, Roth BL: H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology. 2003 Mar;28(3):519-26.
GroupsApproved
Direct ClassificationThioxanthenes
SMILESCN(C)S(=O)(=O)C1=CC2=C(SC3=CC=CC=C3C2=CCCN2CCN(C)CC2)C=C1
Pathways
PharmGKBPA451669
ChEMBLCHEMBL1201