Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB06446
Drug NameDotarizine
Target IDBE0000451
UniProt IDP28223
Regulation Type
PubMed IDs8830881; 9379783
CitationsBelcheva S, Petkov VD, Konstantinova E, Petkov VV, Boyanova E: Effects on nociception of the Ca2+ and 5-HT antagonist dotarizine and other 5-HT receptor agonists and antagonists. Acta Physiol Pharmacol Bulg. 1995;21(4):93-8.@@Farre M, Roset PN, Llorente M, Marquez M, Albet C, Perez JA, Herrero E, Ortiz JA: Clinical pharmacokinetics and tolerability of dotarizine in healthy subjects after single and multiple oral administration. Methods Find Exp Clin Pharmacol. 1997 Jun;19(5):343-50.
GroupsInvestigational
Direct ClassificationDiphenylmethanes
SMILESC(CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1)CC1(OCCO1)C1=CC=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL2106316