Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10016573HBVENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TVIS44041305HTLV-1ENSG00000102468.11protein_codingHTR2ANoNo3356P28223
TCGA Plot Options
Drug Information
GeneHTR2A
DrugBank IDDB01537
Drug Name4-Bromo-2,5-dimethoxyphenethylamine
Target IDBE0000451
UniProt IDP28223
Regulation Typepartial agonist
PubMed IDs15006903; 17337633
CitationsVillalobos CA, Bull P, Saez P, Cassels BK, Huidobro-Toro JP: 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes. Br J Pharmacol. 2004 Apr;141(7):1167-74. Epub 2004 Mar 8.@@Moya PR, Berg KA, Gutierrez-Hernandez MA, Saez-Briones P, Reyes-Parada M, Cassels BK, Clarke WP: Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J Pharmacol Exp Ther. 2007 Jun;321(3):1054-61. Epub 2007 Mar 2.
GroupsExperimental; Illicit
Direct ClassificationDimethoxybenzenes
SMILESCOC1=CC(Br)=C(OC)C=C1CCN
Pathways
PharmGKB
ChEMBLCHEMBL292821