DegronMD

Uniprot ID: Q02505

Source protein: Mucin-3A

Source gene: MUC3A

Class: DEG_SPOP_SBC_1

Location: 1380:1384

E3 ligase: SPOP

DEGRON score: 0.6573

ASA_SCORE: 94.46

COIL: 0.9048

CONS_SCORE: 0.4534

DSS_SCORE: 0.5824

HELIX: 0.0092

FCONS_SCORE: 1

RIG_SCORE: 0.7157

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A1380T	SIDM00660	Colorectal Carcinoma	GDSC	AMTST	DEG_SPOP_SBC_1	0.7139

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02505	Mucin-3A	DEG_SPOP_SBC_1	1380:1384	AMTST	SPOP	0.6573	More...
Q8WXI7	Mucin-16	DEG_SPOP_SBC_1	3003:3007	AMTST	SPOP	0.95	More...
Q9H987	Synaptopodin 2-like protein	DEG_SPOP_SBC_1	575:579	AMTST	SPOP	0.9382	More...
Q9NP60	X-linked interleukin-1 receptor accessory protein-like 2	DEG_SPOP_SBC_1	588:592	AMTST	SPOP	0.5216	More...
Q9UGU0	Transcription factor 20	DEG_SPOP_SBC_1	1463:1467	AMTST	SPOP	0.5189	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons