DegronMD

Uniprot ID: Q9H992

Source protein: E3 ubiquitin-protein ligase MARCHF7

Source gene: MARCHF7

Class: DEG_APCC_KENBOX_2

Location: 186:190

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9681

ASA_SCORE: 92.6

COIL: 0.7436

CONS_SCORE: 0.7207

DSS_SCORE: 0.6491

HELIX: 0.165

FCONS_SCORE: 1.1407

RIG_SCORE: 0.6407

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O43164	E3 ubiquitin-protein ligase Praja-2	DEG_APCC_KENBOX_2	72:76	PKENS	APC,CDC20,FZR1	0.9147	More...
Q6EMB2	Tubulin polyglutamylase TTLL5	DEG_APCC_KENBOX_2	630:634	PKENS	APC,CDC20,FZR1	0.983	More...
Q86W42	THO complex subunit 6 homolog	DEG_APCC_KENBOX_2	136:140	PKENS	APC,CDC20,FZR1	0.6367	More...
Q9H992	E3 ubiquitin-protein ligase MARCHF7	DEG_APCC_KENBOX_2	186:190	PKENS	APC,CDC20,FZR1	0.9681	More...
Q9P260	RAB11-binding protein RELCH	DEG_APCC_KENBOX_2	449:453	PKENS	APC,CDC20,FZR1	0.7041	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons