DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
VHTTS
Uniprot ID:
A8MWA6
Source protein:
Putative protein FAM90A22
Source gene:
FAM90A22
Class:
DEG_SPOP_SBC_1
Location:
152:156
E3 ligase:
SPOP
DEGRON score:
0.9225
ASA_SCORE:
87.24
COIL:
0.9146
CONS_SCORE:
0.2645
DSS_SCORE:
0.6172
HELIX:
0.0308
FCONS_SCORE:
0.6823
RIG_SCORE:
0.6893
Degron related mutations and impact score
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Degron
Degron class
Impact score
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Drug responses associated with FAM90A22 mutations
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All proteins holding degron of VHTTS
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NE21
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.7681
More...
Q8IWE5
Pleckstrin homology domain-containing family M member 2
DEG_SPOP_SBC_1
288:292
VHTTS
SPOP
0.8723
More...
Q86YD7
Protein FAM90A1
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.6922
More...
A6NDY2
Putative protein FAM90A10
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.6026
More...
P0C7W8
Putative protein FAM90A13P
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.9301
More...
P0C7W9
Putative protein FAM90A14
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.9792
More...
P0C7V4
Putative protein FAM90A15P
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.72
More...
A8MWA6
Putative protein FAM90A22
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.9225
More...
A8MXZ1
Putative protein FAM90A23
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.5879
More...
P0C7X0
Putative protein FAM90A24P
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.9832
More...
D6RGX4
Putative protein FAM90A26
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.976
More...
Q658T7
Putative protein FAM90A2P
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.8547
More...
A6NKC0
Putative protein FAM90A7
DEG_SPOP_SBC_1
152:156
VHTTS
SPOP
0.7459
More...
Q92618
Zinc finger protein 516
DEG_SPOP_SBC_1
1134:1138
VHTTS
SPOP
0.9673
More...
Showing 1 to 14 of 14 entries
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