Summary ?
GeneID10553
SymbolHTATIP2
SynonymsCC3|SDR44U1|TIP30
DescriptionHIV-1 Tat interactive protein 2
ReferenceMIM:605628|HGNC:HGNC:16637|Ensembl:ENSG00000109854|HPRD:09288|Vega:OTTHUMG00000166015
Gene typeprotein-coding
Map location11p15.1
Pascal p-value0.287
Sherlock p-value0.109
DMG1 (# studies)
eGeneCaudate basal ganglia
Cortex
Hippocampus
Nucleus accumbens basal ganglia
Putamen basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg255335561120385280HTATIP23.95E-6-0.740.009DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs110255241120379276HTATIP2ENSG00000109854.99.297E-120-5955gtex_brain_putamen_basal
rs110255251120379963HTATIP2ENSG00000109854.91.187E-110-5268gtex_brain_putamen_basal
rs47579401120382453HTATIP2ENSG00000109854.91.367E-110-2778gtex_brain_putamen_basal
rs123605931120384003HTATIP2ENSG00000109854.91.203E-110-1228gtex_brain_putamen_basal
rs3977534611120384886HTATIP2ENSG00000109854.93.251E-110-345gtex_brain_putamen_basal
rs104376081120385606HTATIP2ENSG00000109854.91.637E-110375gtex_brain_putamen_basal
rs108333121120386301HTATIP2ENSG00000109854.95.031E-1101070gtex_brain_putamen_basal
rs104375831120386761HTATIP2ENSG00000109854.94.793E-1101530gtex_brain_putamen_basal
rs110255351120387062HTATIP2ENSG00000109854.93.709E-901831gtex_brain_putamen_basal
rs108333131120387375HTATIP2ENSG00000109854.93.954E-1102144gtex_brain_putamen_basal
rs79251361120387798HTATIP2ENSG00000109854.94.687E-902567gtex_brain_putamen_basal
rs79285031120388097HTATIP2ENSG00000109854.92.638E-902866gtex_brain_putamen_basal
rs71039341120389743HTATIP2ENSG00000109854.91.026E-904512gtex_brain_putamen_basal
rs71122131120391426HTATIP2ENSG00000109854.99.743E-906195gtex_brain_putamen_basal
rs116079821120395162HTATIP2ENSG00000109854.91.192E-609931gtex_brain_putamen_basal
rs79373331120499112HTATIP2ENSG00000109854.97.613E-70113881gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ONKEN UVEAL MELANOMA UP 783507All SZGR 2.0 genes in this pathway
KIM RESPONSE TO TSA AND DECITABINE UP 12973All SZGR 2.0 genes in this pathway
SAMOLS TARGETS OF KHSV MIRNAS DN 6235All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE UP 423283All SZGR 2.0 genes in this pathway
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN 663425All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS UP 306188All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS UP 290177All SZGR 2.0 genes in this pathway
RODRIGUES NTN1 TARGETS DN 158102All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 UP 380236All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418263All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557331All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS DN 459276All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN 805505All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS F DN 3324All SZGR 2.0 genes in this pathway
ROVERSI GLIOMA LOH REGIONS 4430All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER 747453All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS UP 414287All SZGR 2.0 genes in this pathway
MANTOVANI VIRAL GPCR SIGNALING UP 8654All SZGR 2.0 genes in this pathway
FRIDMAN SENESCENCE UP 7760All SZGR 2.0 genes in this pathway
FRIDMAN IMMORTALIZATION DN 3424All SZGR 2.0 genes in this pathway
KOYAMA SEMA3B TARGETS UP 292168All SZGR 2.0 genes in this pathway
BENPORATH ES CORE NINE CORRELATED 10068All SZGR 2.0 genes in this pathway
MORI PLASMA CELL UP 5129All SZGR 2.0 genes in this pathway
LEE LIVER CANCER MYC UP 5430All SZGR 2.0 genes in this pathway
LEE LIVER CANCER MYC TGFA UP 6140All SZGR 2.0 genes in this pathway
LEE LIVER CANCER ACOX1 UP 6440All SZGR 2.0 genes in this pathway
UEDA PERIFERAL CLOCK 169111All SZGR 2.0 genes in this pathway
SMITH LIVER CANCER 4527All SZGR 2.0 genes in this pathway
GERY CEBP TARGETS 12690All SZGR 2.0 genes in this pathway
GALE APL WITH FLT3 MUTATED UP 5635All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN 225163All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS MATURE CELL 293160All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 16911088All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487303All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE DN 373196All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS UP 388234All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3 UNMETHYLATED 536296All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE UP 181106All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS 535325All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 UP 430288All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549316All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137655All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE VIA P38 COMPLETE 227151All SZGR 2.0 genes in this pathway
FOSTER KDM1A TARGETS UP 266142All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL DN 428246All SZGR 2.0 genes in this pathway