Gene Page: TUBGCP4
Summary ?
GeneID | 27229 |
Symbol | TUBGCP4 |
Synonyms | 76P|GCP-4|GCP4|Grip76|MCCRP3 |
Description | tubulin gamma complex associated protein 4 |
Reference | MIM:609610|HGNC:HGNC:16691|HPRD:10616| |
Gene type | protein-coding |
Map location | 15q15 |
Pascal p-value | 6.025E-4 |
Sherlock p-value | 0.253 |
eGene | Cortex Putamen basal ganglia Myers' cis & trans |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs10497672 | 0 | TUBGCP4 | 27229 | 0.04 | trans | |||
rs884704 | 15 | 43691150 | TUBGCP4 | ENSG00000137822.8 | 8.90251E-6 | 0.05 | 29731 | gtex_brain_putamen_basal |
rs201576404 | 15 | 43696166 | TUBGCP4 | ENSG00000137822.8 | 8.20396E-6 | 0.05 | 34747 | gtex_brain_putamen_basal |
rs397730626 | 15 | 43696168 | TUBGCP4 | ENSG00000137822.8 | 8.20396E-6 | 0.05 | 34749 | gtex_brain_putamen_basal |
rs1837960 | 15 | 43698602 | TUBGCP4 | ENSG00000137822.8 | 8.06416E-6 | 0.05 | 37183 | gtex_brain_putamen_basal |
rs1837959 | 15 | 43698679 | TUBGCP4 | ENSG00000137822.8 | 8.06416E-6 | 0.05 | 37260 | gtex_brain_putamen_basal |
rs2242067 | 15 | 43699303 | TUBGCP4 | ENSG00000137822.8 | 8.3873E-6 | 0.05 | 37884 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
![Not available](/SZGR/GeneImg/TUBGCP4_DE_GTEx.png)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
AP2B1 | ADTB2 | AP105B | AP2-BETA | CLAPB1 | DKFZp781K0743 | adaptor-related protein complex 2, beta 1 subunit | Two-hybrid | BioGRID | 16189514 |
CCDC85B | DIPA | coiled-coil domain containing 85B | Two-hybrid | BioGRID | 16189514 |
FBF1 | Alb | FBF-1 | FLJ00103 | Fas (TNFRSF6) binding factor 1 | Two-hybrid | BioGRID | 16189514 |
GFAP | FLJ45472 | glial fibrillary acidic protein | Two-hybrid | BioGRID | 16189514 |
GOLGA2 | GM130 | MGC20672 | golgi autoantigen, golgin subfamily a, 2 | Two-hybrid | BioGRID | 16189514 |
KCTD17 | FLJ12242 | FLJ98761 | potassium channel tetramerisation domain containing 17 | Two-hybrid | BioGRID | 16189514 |
KRT15 | CK15 | K15 | K1CO | keratin 15 | Two-hybrid | BioGRID | 16189514 |
KRT18 | CYK18 | K18 | keratin 18 | Two-hybrid | BioGRID | 16189514 |
MAD1L1 | HsMAD1 | MAD1 | PIG9 | TP53I9 | TXBP181 | MAD1 mitotic arrest deficient-like 1 (yeast) | Two-hybrid | BioGRID | 16189514 |
OBFC1 | FLJ22559 | RP11-541N10.2 | bA541N10.2 | oligonucleotide/oligosaccharide-binding fold containing 1 | Two-hybrid | BioGRID | 16189514 |
PAK7 | KIAA1264 | MGC26232 | PAK5 | p21 protein (Cdc42/Rac)-activated kinase 7 | Two-hybrid | BioGRID | 16189514 |
RPRD1B | C20orf77 | CREPT | DKFZp434P0735 | FLJ44520 | dJ1057B20.2 | regulation of nuclear pre-mRNA domain containing 1B | Two-hybrid | BioGRID | 16189514 |
SDSL | SDS-RS1 | serine dehydratase-like | Two-hybrid | BioGRID | 16189514 |
SPERT | CBY2 | FLJ35810 | NURIT | spermatid associated | Two-hybrid | BioGRID | 16189514 |
USHBP1 | AIEBP | FLJ38709 | FLJ90681 | MCC2 | Usher syndrome 1C binding protein 1 | Two-hybrid | BioGRID | 16189514 |
VIM | FLJ36605 | vimentin | Two-hybrid | BioGRID | 16189514 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
SOTIRIOU BREAST CANCER GRADE 1 VS 3 DN | 52 | 34 | All SZGR 2.0 genes in this pathway |
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
BIDUS METASTASIS UP | 214 | 134 | All SZGR 2.0 genes in this pathway |
DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
WOOD EBV EBNA1 TARGETS UP | 110 | 71 | All SZGR 2.0 genes in this pathway |
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | 584 | 395 | All SZGR 2.0 genes in this pathway |
RICKMAN METASTASIS UP | 344 | 180 | All SZGR 2.0 genes in this pathway |
UEDA CENTRAL CLOCK | 88 | 62 | All SZGR 2.0 genes in this pathway |
BYSTRYKH HEMATOPOIESIS STEM CELL QTL CIS | 128 | 77 | All SZGR 2.0 genes in this pathway |
CHESLER BRAIN QTL CIS | 75 | 51 | All SZGR 2.0 genes in this pathway |
BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL CIS | 65 | 38 | All SZGR 2.0 genes in this pathway |
LEE LIVER CANCER MYC TGFA UP | 61 | 40 | All SZGR 2.0 genes in this pathway |
MANALO HYPOXIA DN | 289 | 166 | All SZGR 2.0 genes in this pathway |
HASLINGER B CLL WITH 13Q14 DELETION | 24 | 18 | All SZGR 2.0 genes in this pathway |
NADLER HYPERGLYCEMIA AT OBESITY | 58 | 35 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 16HR UP | 225 | 139 | All SZGR 2.0 genes in this pathway |
BACOLOD RESISTANCE TO ALKYLATING AGENTS DN | 60 | 45 | All SZGR 2.0 genes in this pathway |
MCCABE BOUND BY HOXC6 | 469 | 239 | All SZGR 2.0 genes in this pathway |
CADWELL ATG16L1 TARGETS DN | 70 | 43 | All SZGR 2.0 genes in this pathway |
MILI PSEUDOPODIA CHEMOTAXIS DN | 457 | 302 | All SZGR 2.0 genes in this pathway |
MILI PSEUDOPODIA HAPTOTAXIS UP | 518 | 299 | All SZGR 2.0 genes in this pathway |
VALK AML CLUSTER 6 | 33 | 22 | All SZGR 2.0 genes in this pathway |
WIERENGA STAT5A TARGETS DN | 213 | 127 | All SZGR 2.0 genes in this pathway |
PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |