Gene Page: ANK1

Summary
GeneID  286
Symbol  ANK1
Synonyms  ANK|SPH1|SPH2
Description  ankyrin 1, erythrocytic
See related  HGNC:492|MIM:182900|Ensembl:ENSG00000029534|HPRD:01693|
Locus tag  -
Gene type  protein-coding
Map location  8p11.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.772 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0437 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005200structural constituent of cytoskeletonTAS8640229 
GO:0008093cytoskeletal adaptor activityTAS11427698 
GO:0030507spectrin bindingNAS8640229 
GO:0019899enzyme bindingTAS11427698 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007010cytoskeleton organizationNAS9430667 
GO:0007165signal transductionIEA-
GO:0006887exocytosisNAS1833445 
GO:0045199maintenance of epithelial cell apical/basal polarityTAS11427698 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonNAS1833445 
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneNAS9430667 
GO:0016323basolateral plasma membraneNAS12409278 
GO:0016529sarcoplasmic reticulumIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
L1CAMCAML1 | CD171 | HSAS | HSAS1 | MASA | MIC5 | N-CAML1 | S10 | SPG1L1 cell adhesion molecule-HPRD,BioGRID11222639 
NBPF3AE2 | DKFZp434D177neuroblastoma breakpoint family, member 3-HPRD9587054 
OBSCNDKFZp666E245 | FLJ14124 | KIAA1556 | KIAA1639 | MGC120409 | MGC120410 | MGC120411 | MGC120412 | MGC138590 | UNC89obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF-HPRD,BioGRID12527750 |12631729 
RHAGCD241 | RH2 | RH50A | Rh50 | Rh50GP | SLC42A1Rh-associated glycoprotein-HPRD,BioGRID12719424 
SLC4A1AE1 | BND3 | CD233 | DI | EMPB3 | EPB3 | FR | MGC116750 | MGC116753 | MGC126619 | MGC126623 | RTA1A | SW | WD | WD1 | WRsolute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)-HPRD6449514 
Affinity Capture-WesternBioGRID8227202 
SLC4A3AE3 | SLC2Csolute carrier family 4, anion exchanger, member 3-HPRD,BioGRID8227202 
SPTA1EL2 | SPTAspectrin, alpha, erythrocytic 1 (elliptocytosis 2)Reconstituted ComplexBioGRID2971657 
SPTAN1(ALPHA)II-SPECTRIN | FLJ44613 | NEASspectrin, alpha, non-erythrocytic 1 (alpha-fodrin)-HPRD492324 |2141335 
|2970468 |2971657 
SPTBHSpTB1spectrin, beta, erythrocyticReconstituted ComplexBioGRID2141335 
TIAM1FLJ36302T-cell lymphoma invasion and metastasis 1-HPRD,BioGRID10893266 
TTNCMD1G | CMH9 | CMPD4 | CONNECTIN | DKFZp451N061 | EOMFC | FLJ26020 | FLJ26409 | FLJ32040 | FLJ34413 | FLJ39564 | FLJ43066 | HMERF | LGMD2J | TMDtitin-HPRD,BioGRID12444090 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS 2319All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP 6437All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
KERLEY_RESPONSE_TO_CISPLATIN_UP 4430All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION 7751All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_8P12_P11_AMPLICON 5732All SZGR genes in this pathway
NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER 9460All SZGR genes in this pathway
WELCH_GATA1_TARGETS 2212All SZGR genes in this pathway
ROSS_AML_OF_FAB_M7_TYPE 6844All SZGR genes in this pathway
SCHURINGA_STAT5A_TARGETS_UP 2113All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA_UP 5233All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
VALK_AML_CLUSTER_7 2816All SZGR genes in this pathway
VALK_AML_CLUSTER_8 2617All SZGR genes in this pathway
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP 4023All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME2 1711All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_DN 187109All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
STEINER_ERYTHROCYTE_MEMBRANE_GENES 1510All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/107229923061A,m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-124.1148214881Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-1286316371Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-1388999061A,m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-1391371441A,m8hsa-miR-139brainUCUACAGUGCACGUGUCU
miR-153101510221A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-218152615321Ahsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-27631637m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-32815641570m8hsa-miR-328brainCUGGCCCUCUCUGCCCUUCCGU
miR-448101610221Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-45210181024m8hsa-miR-452UGUUUGCAGAGGAAACUGAGAC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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