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Gene Page: NR3C1

Summary

GeneID

2908

Symbol

NR3C1

Synonyms

GCCR|GCR|GR|GRL

Description

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Locus tag

Gene type

protein-coding

Map location

5q31.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0032

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00459

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01718

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.1127

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MYRIP

0.77

RAPGEFL1

0.73

0.76

IQSEC2

0.73

0.74

GARNL4

0.72

0.73

LRRK1

0.72

0.71

KIAA1045

0.72

0.74

PITPNM3

0.72

0.74

GDA

0.71

0.75

PITPNM2

0.71

0.73

AJAP1

0.70

Top 10 negatively co-expressed genes

BCL7C

-0.36

-0.40

UXT

-0.35

-0.31

SNRPG

-0.34

-0.39

RPL35

-0.34

-0.38

RPS12

-0.34

-0.39

C21orf57

-0.34

-0.36

RPL27

-0.34

-0.32

RPL24

-0.34

-0.31

RPL37

-0.33

-0.41

RPS27A

-0.33

-0.35

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004883

glucocorticoid receptor activity

TAS

8621628

GO:0003700

transcription factor activity

TAS

7769088 |10903900

GO:0005496

steroid binding

IEA

GO:0005515

protein binding

IPI

9079630 |10364267 |11266503
|12773562

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

GO:0043565

sequence-specific DNA binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006366

transcription from RNA polymerase II promoter

TAS

8621628

GO:0007165

signal transduction

TAS

7769088

GO:0007530

sex determination

IEA

GO:0016568

chromatin modification

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

TAS

9873044

GO:0005730

nucleolus

IDA

18029348

GO:0005737

cytoplasm

TAS

9873044

GO:0005759

mitochondrial matrix

TAS

10887960

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ADA	-	adenosine deaminase	-	HPRD,BioGRID	9154805
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD,BioGRID	9162033
ARPC5	ARC16 \| MGC88523 \| dJ127C7.3 \| p16-Arc	actin related protein 2/3 complex, subunit 5, 16kDa	Two-hybrid	BioGRID	10508170
BAG1	RAP46	BCL2-associated athanogene	-	HPRD,BioGRID	11101523
CALR	CRT \| FLJ26680 \| RO \| SSA \| cC1qR	calreticulin	-	HPRD,BioGRID	8107808 \|9089287
CEBPA	C/EBP-alpha \| CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	Reconstituted Complex	BioGRID	9817600
CEBPA	C/EBP-alpha \| CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	-	HPRD	11818365
CEBPB	C/EBP-beta \| CRP2 \| IL6DBP \| LAP \| MGC32080 \| NF-IL6 \| TCF5	CCAAT/enhancer binding protein (C/EBP), beta	-	HPRD,BioGRID	9817600
COPS6	CSN6 \| MOV34-34KD	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	-	HPRD	12237292
CREB1	CREB \| MGC9284	cAMP responsive element binding protein 1	-	HPRD,BioGRID	7621901 \|8449898
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD,BioGRID	9649342
DAP3	DAP-3 \| DKFZp686G12159 \| MGC126058 \| MGC126059 \| MRP-S29 \| MRPS29 \| bMRP-10	death associated protein 3	-	HPRD,BioGRID	10903152 \|12099703
DAXX	BING2 \| DAP6 \| EAP1 \| MGC126245 \| MGC126246	death-domain associated protein	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	12595526
DDC	AADC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	Reconstituted Complex	BioGRID	12864730
DDX54	DP97 \| MGC2835	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	-	HPRD,BioGRID	12466272
ECD	GCR2 \| HSGT1	ecdysoneless homolog (Drosophila)	-	HPRD,BioGRID	9928932
ETS1	ETS-1 \| EWSR2 \| FLJ10768	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	-	HPRD	11279115
ETS2	ETS2IT1	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	-	HPRD,BioGRID	11279115
FKBP4	FKBP52 \| FKBP59 \| HBI \| Hsp56 \| PPIase \| p52	FK506 binding protein 4, 59kDa	-	HPRD,BioGRID	8341706
HMGB1	DKFZp686A04236 \| HMG1 \| HMG3 \| SBP-1	high-mobility group box 1	Reconstituted Complex	BioGRID	9671457
HMGB2	HMG2	high-mobility group box 2	Reconstituted Complex	BioGRID	9671457
HNRNPU	HNRPU \| SAF-A \| U21.1	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	-	HPRD,BioGRID	9353307
HOXB1	HOX2 \| HOX2I \| Hox-2.9 \| MGC116843 \| MGC116844 \| MGC116845	homeobox B1	-	HPRD,BioGRID	12487626
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	8621522 \|8645634 \|8898375 \|9334248 \|10066374
HSPA1A	FLJ54303 \| FLJ54370 \| FLJ54392 \| FLJ54408 \| FLJ75127 \| HSP70-1 \| HSP70-1A \| HSP70I \| HSP72 \| HSPA1 \| HSPA1B	heat shock 70kDa protein 1A	-	HPRD,BioGRID	12093808
HSPD1	CPN60 \| GROEL \| HSP60 \| HSP65 \| HuCHA60 \| SPG13	heat shock 60kDa protein 1 (chaperonin)	Two-hybrid	BioGRID	10508170
IDE	FLJ35968 \| INSULYSIN	insulin-degrading enzyme	-	HPRD	8051160
IL1RN	ICIL-1RA \| IL-1ra3 \| IL1F3 \| IL1RA \| IRAP \| MGC10430	interleukin 1 receptor antagonist	-	HPRD	10948677
JARID1A	KDM5A \| RBBP2 \| RBP2	jumonji, AT rich interactive domain 1A	Reconstituted Complex	BioGRID	11358960
JARID1A	KDM5A \| RBBP2 \| RBP2	jumonji, AT rich interactive domain 1A	Rbp2 interacts with GR. This interaction was modeled on a demonstrated interaction between human Rbp2 and rat GR.	BIND	11358960
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD	7823959 \|8733011
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	Reconstituted Complex	BioGRID	14522952
MED1	CRSP1 \| CRSP200 \| DRIP205 \| DRIP230 \| MGC71488 \| PBP \| PPARBP \| PPARGBP \| RB18A \| TRAP220 \| TRIP2	mediator complex subunit 1	Reconstituted Complex	BioGRID	10508170 \|11266503
MED14	CRSP150 \| CRSP2 \| CSRP \| CXorf4 \| DRIP150 \| EXLM1 \| MGC104513 \| RGR1 \| TRAP170	mediator complex subunit 14	-	HPRD,BioGRID	10508170
NCL	C23 \| FLJ45706	nucleolin	-	HPRD,BioGRID	8530516 \|11162542
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	nuclear receptor coactivator 1	-	HPRD	12118039 \|12569182 \|12917342
NCOA1		nuclear receptor coactivator 1	in vitro Reconstituted Complex Two-hybrid	BioGRID	11266503 \|12118039
NCOA2	GRIP1 \| KAT13C \| MGC138808 \| NCoA-2 \| TIF2	nuclear receptor coactivator 2	-	HPRD,BioGRID	12151000
NCOA2	GRIP1 \| KAT13C \| MGC138808 \| NCoA-2 \| TIF2	nuclear receptor coactivator 2	GR-alpha interacts with GRIP1.	BIND	11704662
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	nuclear receptor coactivator 3	Affinity Capture-Western Reconstituted Complex	BioGRID	11266503 \|12917342
NCOA4	ARA70 \| DKFZp762E1112 \| ELE1 \| PTC3 \| RFG	nuclear receptor coactivator 4	Two-hybrid	BioGRID	10517667
NCOA6	AIB3 \| ANTP \| ASC2 \| HOX1.1 \| HOXA7 \| KIAA0181 \| NRC \| PRIP \| RAP250 \| TRBP	nuclear receptor coactivator 6	-	HPRD,BioGRID	10567404
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	nuclear receptor co-repressor 1	-	HPRD,BioGRID	12011091
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	nuclear receptor co-repressor 2	-	HPRD,BioGRID	12011091
NEDD4L	FLJ33870 \| KIAA0439 \| NEDD4-2 \| RSP5 \| hNedd4-2	neural precursor cell expressed, developmentally down-regulated 4-like	Reconstituted Complex	BioGRID	9649342
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	-	HPRD,BioGRID	7823959 \|8290595
NFKB2	LYT-10 \| LYT10	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	-	HPRD,BioGRID	7823959
NR2F6	EAR-2 \| EAR2 \| ERBAL2	nuclear receptor subfamily 2, group F, member 6	-	HPRD,BioGRID	10713182
NR3C1	GCCR \| GCR \| GR \| GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	Co-crystal Structure	BioGRID	12151000
NR3C2	MCR \| MGC133092 \| MLR \| MR	nuclear receptor subfamily 3, group C, member 2	-	HPRD,BioGRID	11154266
NRIP1	FLJ77253 \| RIP140	nuclear receptor interacting protein 1	Affinity Capture-Western Reconstituted Complex	BioGRID	10364267 \|11266503 \|12773562
NRIP1	FLJ77253 \| RIP140	nuclear receptor interacting protein 1	-	HPRD	10364267 \|12773562
ONECUT1	HNF-6 \| HNF6 \| HNF6A	one cut homeobox 1	-	HPRD,BioGRID	10430878
PBX1	DKFZp686B09108 \| MGC126627	pre-B-cell leukemia homeobox 1	Affinity Capture-Western	BioGRID	12487626
PELP1	HMX3 \| MNAR \| P160	proline, glutamate and leucine rich protein 1	-	HPRD,BioGRID	12415108
PIAS2	MGC102682 \| MIZ1 \| PIASX \| PIASX-ALPHA \| PIASX-BETA \| SIZ2 \| ZMIZ4 \| miz	protein inhibitor of activated STAT, 2	Reconstituted Complex	BioGRID	11117529
POU1F1	GHF-1 \| PIT1 \| Pit-1	POU class 1 homeobox 1	-	HPRD,BioGRID	9426156
POU2F1	OCT1 \| OTF1	POU class 2 homeobox 1	-	HPRD,BioGRID	9584182 \|10480874 \|10490647 \|14522952
POU2F2	OCT2 \| OTF2 \| Oct-2	POU class 2 homeobox 2	-	HPRD,BioGRID	9584182 \|10480874 \|10490647
PPARGC1A	LEM6 \| PGC-1(alpha) \| PGC-1v \| PGC1 \| PGC1A \| PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	-	HPRD,BioGRID	10713165
PRPF6	ANT-1 \| C20orf14 \| TOM \| U5-102K \| hPrp6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	-	HPRD	12039962
PSMC3IP	GT198 \| HOP2 \| HUMGT198A \| TBPIP	PSMC3 interacting protein	-	HPRD,BioGRID	11739747
PTGES3	P23 \| TEBP \| cPGES	prostaglandin E synthase 3 (cytosolic)	-	HPRD,BioGRID	10691735
PTMS	ParaT	parathymosin	-	HPRD	10601862
RAD9A	RAD9	RAD9 homolog A (S. pombe)	Reconstituted Complex	BioGRID	14966297
RAF1	CRAF \| NS5 \| Raf-1 \| c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1	-	HPRD,BioGRID	11005817
RAN	ARA24 \| Gsp1 \| TC4	RAN, member RAS oncogene family	Two-hybrid	BioGRID	10508170
RANBP9	RANBPM	RAN binding protein 9	Affinity Capture-Western Two-hybrid	BioGRID	12361945
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Affinity Capture-Western in vitro in vivo	BioGRID	7659084 \|8290595 \|10995388
RELA	MGC131774 \| NFKB3 \| p65		-	HPRD	7659084 \|10995388
SELENBP1	FLJ13813 \| LPSB \| SP56 \| hSBP \| hSP56	selenium binding protein 1	-	HPRD	8157642
SFN	YWHAS	stratifin	-	HPRD,BioGRID	12730237
SLC25A4	AAC1 \| ANT \| ANT1 \| PEO2 \| PEO3 \| T1	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	-	HPRD	12039962
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	-	HPRD,BioGRID	10518526 \|12902338
SMARCA2	BAF190 \| BRM \| FLJ36757 \| MGC74511 \| SNF2 \| SNF2L2 \| SNF2LA \| SWI2 \| Sth1p \| hBRM \| hSNF2a	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	-	HPRD,BioGRID	8223438
SMARCA4	BAF190 \| BRG1 \| FLJ39786 \| SNF2 \| SNF2-BETA \| SNF2L4 \| SNF2LB \| SWI2 \| hSNF2b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Affinity Capture-Western Reconstituted Complex	BioGRID	10688647 \|12917342
SMARCB1	BAF47 \| INI1 \| RDT \| SNF5 \| SNF5L1 \| Sfh1p \| Snr1 \| hSNFS	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	-	HPRD	10688647
SMARCC1	BAF155 \| CRACC1 \| Rsc8 \| SRG3 \| SWI3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	Affinity Capture-Western	BioGRID	12917342
SMARCD1	BAF60A \| CRACD1 \| Rsc6p	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	-	HPRD,BioGRID	12917342
SMARCE1	BAF57	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	-	HPRD,BioGRID	12917342
STAT3	APRF \| FLJ20882 \| HIES \| MGC16063	signal transducer and activator of transcription 3 (acute-phase response factor)	-	HPRD,BioGRID	9388192 \|14522952
STAT5A	MGF \| STAT5	signal transducer and activator of transcription 5A	-	HPRD	9528750
STAT5B	STAT5	signal transducer and activator of transcription 5B	-	HPRD,BioGRID	8878484 \|9528750 \|11158330
SUMO1	DAP-1 \| GMP1 \| OFC10 \| PIC1 \| SENP2 \| SMT3 \| SMT3C \| SMT3H3 \| SUMO-1 \| UBL1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	-	HPRD	12193561
SVIL	DKFZp686A17191	supervillin	Two-hybrid	BioGRID	11792840
TADA2L	ADA2 \| ADA2A \| FLJ12705 \| KL04P \| hADA2	transcriptional adaptor 2 (ADA2 homolog, yeast)-like	Reconstituted Complex	BioGRID	9649342
TBP	GTF2D \| GTF2D1 \| MGC117320 \| MGC126054 \| MGC126055 \| SCA17 \| TFIID	TATA box binding protein	-	HPRD,BioGRID	9649342
TDG	-	thymine-DNA glycosylase	Reconstituted Complex	BioGRID	12874288
TGFB1I1	ARA55 \| HIC-5 \| HIC5 \| TSC-5	transforming growth factor beta 1 induced transcript 1	-	HPRD,BioGRID	10848625
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	11080152
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	p53 interacts with GR. This interaction was modelled on a demonstrated interaction between p53 from an unspecified species and GR from an unspecified species.	BIND	9215863
TRIM24	PTC6 \| RNF82 \| TF1A \| TIF1 \| TIF1A \| TIF1ALPHA \| hTIF1	tripartite motif-containing 24	-	HPRD,BioGRID	9115274
TRIM28	FLJ29029 \| KAP1 \| RNF96 \| TF1B \| TIF1B	tripartite motif-containing 28	-	HPRD,BioGRID	9742105
TSG101	TSG10 \| VPS23	tumor susceptibility gene 101	-	HPRD,BioGRID	10508170
TXN	DKFZp686B1993 \| MGC61975 \| TRX \| TRX1	thioredoxin	-	HPRD,BioGRID	9915858
UBE2I	C358B7.1 \| P18 \| UBC9	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	-	HPRD	11812797
YWHAH	YWHA1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	-	HPRD,BioGRID	9079630 \|11266503 \|12730237
ZBTB16	PLZF \| ZNF145	zinc finger and BTB domain containing 16	-	HPRD,BioGRID	14521715

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	272	195	All SZGR genes in this pathway
BIOCARTA_GCR_PATHWAY	22	17	All SZGR genes in this pathway
BIOCARTA_NTHI_PATHWAY	24	20	All SZGR genes in this pathway
PID_SMAD2_3NUCLEAR_PATHWAY	82	63	All SZGR genes in this pathway
PID_HDAC_CLASSII_PATHWAY	34	27	All SZGR genes in this pathway
PID_HNF3B_PATHWAY	45	37	All SZGR genes in this pathway
PID_REG_GR_PATHWAY	82	60	All SZGR genes in this pathway
PID_AR_TF_PATHWAY	53	38	All SZGR genes in this pathway
PID_AP1_PATHWAY	70	60	All SZGR genes in this pathway
REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION	36	27	All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	352	181	All SZGR genes in this pathway
REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	49	36	All SZGR genes in this pathway
REACTOME_CIRCADIAN_CLOCK	53	40	All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_UP	201	125	All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP	255	177	All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN	463	290	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	455	304	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	460	312	All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP	306	188	All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN	367	220	All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN	291	176	All SZGR genes in this pathway
KIM_WT1_TARGETS_UP	214	155	All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP	171	112	All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP	130	85	All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_DN	91	58	All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_UP	77	62	All SZGR genes in this pathway
VANHARANTA_UTERINE_FIBROID_DN	67	45	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP	191	128	All SZGR genes in this pathway
BUSA_SAM68_TARGETS_UP	7	6	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	855	609	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	483	336	All SZGR genes in this pathway
WANG_HCP_PROSTATE_CANCER	111	69	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP	127	79	All SZGR genes in this pathway
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN	26	19	All SZGR genes in this pathway
WOTTON_RUNX_TARGETS_DN	29	18	All SZGR genes in this pathway
BENPORATH_CYCLING_GENES	648	385	All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_SUBSET	33	20	All SZGR genes in this pathway
ROZANOV_MMP14_CORRELATED	11	9	All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_UP	266	171	All SZGR genes in this pathway
BYSTROEM_CORRELATED_WITH_IL5_DN	64	47	All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_UP	38	25	All SZGR genes in this pathway
GRANDVAUX_IRF3_TARGETS_UP	15	12	All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP	182	119	All SZGR genes in this pathway
ZHAN_V2_LATE_DIFFERENTIATION_GENES	45	34	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL	293	160	All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP	314	201	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_DN	56	37	All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C2	54	39	All SZGR genes in this pathway
LEONARD_HYPOXIA	47	35	All SZGR genes in this pathway
ZHU_CMV_8_HR_DN	53	40	All SZGR genes in this pathway
ZHU_CMV_24_HR_DN	91	64	All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D7	40	21	All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN	312	203	All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP	198	132	All SZGR genes in this pathway
ZHU_CMV_ALL_DN	128	93	All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN	318	220	All SZGR genes in this pathway
BURTON_ADIPOGENESIS_11	57	40	All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN	434	302	All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G6	153	112	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN	160	101	All SZGR genes in this pathway
BILD_CTNNB1_ONCOGENIC_SIGNATURE	82	52	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	953	554	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP	783	442	All SZGR genes in this pathway
LOPES_METHYLATED_IN_COLON_CANCER_DN	28	26	All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	196	137	All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN	409	268	All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN	281	179	All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP	673	430	All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP	602	364	All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP	601	369	All SZGR genes in this pathway
AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53	109	63	All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_DN	101	65	All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE	242	168	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP	374	247	All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002	429	260	All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA	447	277	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP	1305	895	All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	196	124	All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN	442	275	All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP	518	299	All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION	422	277	All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED	351	238	All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_VINBLASTINE	18	12	All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2	182	102	All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN	91	56	All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP	134	85	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN	336	211	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	898	516	All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN	229	135	All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN	321	200	All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP	344	215	All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A	770	480	All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_COMPLETE	227	151	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	2	9	1A,m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124.1	2	9	1A,m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	20	26	1A	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-142-3p	135	141	1A	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-142-5p	531	537	1A	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-18	1378	1385	1A,m8	hsa-miR-18a	UAAGGUGCAUCUAGUGCAGAUA
miR-18	1378	1385	1A,m8	hsa-miR-18b	UAAGGUGCAUCUAGUGCAGUUA
miR-181	2254	2260	m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-183	1287	1294	1A,m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-200bc/429	739	745	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-204/211	480	487	1A,m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
				hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
				hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
				hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-218	2501	2507	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-22	611	618	1A,m8	hsa-miR-22^brain	AAGCUGCCAGUUGAAGAACUGU
miR-30-3p	1480	1487	1A,m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	1480	1487	1A,m8	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC
miR-30-5p	460	466	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-328	154	161	1A,m8	hsa-miR-328^brain	CUGGCCCUCUCUGCCCUUCCGU
miR-377	663	670	1A,m8	hsa-miR-377	AUCACACAAAGGCAACUUUUGU
miR-410	1687	1694	1A,m8	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-496	2135	2141	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-543	2255	2262	1A,m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.