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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PACSIN1

Summary

GeneID

29993

Symbol

PACSIN1

Synonyms

KIAA1379|SDPI

Description

protein kinase C and casein kinase substrate in neurons 1

Locus tag

Gene type

protein-coding

Map location

6p21.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.033

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.04433

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004672

protein kinase activity

NAS

GO:0008092

cytoskeletal protein binding

IEA

GO:0016301

kinase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0045806

negative regulation of endocytosis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

GO:0005737

cytoplasm

NAS

GO:0030137

COPI-coated vesicle

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARHGAP17	DKFZp564A1363 \| FLJ37567 \| FLJ43368 \| MGC87805 \| MST066 \| MST110 \| MSTP038 \| MSTP066 \| MSTP110 \| NADRIN \| RICH1 \| WBP15	Rho GTPase activating protein 17	Reconstituted Complex	BioGRID	11431473
DNM1	DNM	dynamin 1	-	HPRD,BioGRID	11082044
DNM1	DNM	dynamin 1	-	HPRD	9950691 \|11082044
HTT	HD \| IT15	huntingtin	-	HPRD,BioGRID	12354780
HTT	HD \| IT15	huntingtin	huntingtin interacts with PACSIN1.	BIND	12354780
MYST2	HBO1 \| HBOA \| KAT7	MYST histone acetyltransferase 2	Two-hybrid	BioGRID	16169070
PACSIN1	KIAA1379 \| SDPI	protein kinase C and casein kinase substrate in neurons 1	-	HPRD,BioGRID	11082044
PACSIN2	SDPII	protein kinase C and casein kinase substrate in neurons 2	Reconstituted Complex Two-hybrid	BioGRID	11082044 \|16189514
PACSIN3	SDPIII	protein kinase C and casein kinase substrate in neurons 3	-	HPRD,BioGRID	11082044
SOS1	GF1 \| GGF1 \| GINGF \| HGF \| NS4	son of sevenless homolog 1 (Drosophila)	-	HPRD	11352907
SYNJ1	INPP5G	synaptojanin 1	Reconstituted Complex	BioGRID	11082044
WASL	DKFZp779G0847 \| MGC48327 \| N-WASP \| NWASP	Wiskott-Aldrich syndrome-like	-	HPRD	9950691\|11179684
WASL	DKFZp779G0847 \| MGC48327 \| N-WASP \| NWASP	Wiskott-Aldrich syndrome-like	Reconstituted Complex	BioGRID	11082044

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
NUYTTEN_EZH2_TARGETS_DN	1024	594	All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_UP	118	66	All SZGR genes in this pathway
RAMALHO_STEMNESS_DN	74	55	All SZGR genes in this pathway
LEIN_NEURON_MARKERS	69	45	All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP	578	341	All SZGR genes in this pathway
MELLMAN_TUT1_TARGETS_DN	47	29	All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2	491	319	All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	435	318	All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE	721	492	All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3	590	403	All SZGR genes in this pathway
SENGUPTA_EBNA1_ANTICORRELATED	173	85	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B	549	316	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	2397	2404	1A,m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	2397	2404	1A,m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-133	2206	2212	m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	2206	2212	m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-18	2034	2040	m8	hsa-miR-18a	UAAGGUGCAUCUAGUGCAGAUA
miR-18	2034	2040	m8	hsa-miR-18b	UAAGGUGCAUCUAGUGCAGUUA
miR-375	136	142	1A	hsa-miR-375	UUUGUUCGUUCGGCUCGCGUGA
miR-9	273	280	1A,m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.