Gene Page: PRPF4B

Summary
GeneID  8899
Symbol  PRPF4B
Synonyms  KIAA0536|PR4H|PRP4|PRP4H|PRP4K|dJ1013A10.1
Description  PRP4 pre-mRNA processing factor 4 homolog B (yeast)
See related  HGNC:17346|MIM:602338|Ensembl:ENSG00000112739|HPRD:09087|
Locus tag  RP5-1013A10.2
Gene type  protein-coding
Map location  6p25.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HSDL10.960.91
CTTNBP2NL0.950.90
CD240.950.89
WDR40A0.950.93
C2orf440.940.91
GNG20.940.91
KBTBD60.940.90
SLAIN20.940.91
ACLY0.940.90
RBM120.940.92
Top 10 negatively co-expressed genes
C5orf53-0.74-0.78
HLA-F-0.71-0.75
AIFM3-0.69-0.72
AF347015.27-0.69-0.84
FBXO2-0.69-0.66
MT-CO2-0.68-0.85
AF347015.31-0.68-0.83
S100B-0.68-0.77
AF347015.33-0.67-0.82
FXYD1-0.67-0.82
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIPI15452250 |16169070 |17513757 
|17620599 
GO:0005524ATP bindingIEA-
GO:0004672protein kinase activityIEA-
GO:0004674protein serine/threonine kinase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006397mRNA processingIEA-
GO:0008380RNA splicingTAS9102632 
GO:0006468protein amino acid phosphorylationIEA-
GO:0006468protein amino acid phosphorylationTAS9102632 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005681spliceosomeIEA-
GO:0005694chromosomeIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HSPB3HSPL27heat shock 27kDa protein 3Two-hybridBioGRID16169070 
PNNDRS | SDK3 | memA | pininpinin, desmosome associated protein-HPRD,BioGRID12077342 
POLR3FMGC13517 | RPC39 | RPC6polymerase (RNA) III (DNA directed) polypeptide F, 39 kDaTwo-hybridBioGRID16169070 
RNPS1E5.1 | MGC117332RNA binding protein S1, serine-rich domainAffinity Capture-MSBioGRID17353931 
SFRS1ASF | MGC5228 | SF2 | SF2p33 | SRp30asplicing factor, arginine/serine-rich 1-HPRD11418604 
YWHAG14-3-3GAMMAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptideAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP 170114All SZGR genes in this pathway
CHOI_ATL_STAGE_PREDICTOR 4424All SZGR genes in this pathway
XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN 2717All SZGR genes in this pathway
DAUER_STAT3_TARGETS_DN 5034All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN 8151All SZGR genes in this pathway
GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 6345All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_DN 5843All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP 156101All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_UP 7353All SZGR genes in this pathway
FINETTI_BREAST_CANCERS_KINOME_GRAY 1510All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
RAY_TARGETS_OF_P210_BCR_ABL_FUSION_UP 1813All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_DN 185116All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP 11370All SZGR genes in this pathway
LU_EZH2_TARGETS_DN 414237All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101752758m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-103/107226122681A,m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-132/21241924198m8hsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-13816601666m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-1391962031A,m8hsa-miR-139brainUCUACAGUGCACGUGUCU
miR-142-5p7998061A,m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-146124412501Ahsa-miR-146aUGAGAACUGAAUUCCAUGGGUU
hsa-miR-146bbrainUGAGAACUGAAUUCCAUAGGCU
hsa-miR-146aUGAGAACUGAAUUCCAUGGGUU
hsa-miR-146bbrainUGAGAACUGAAUUCCAUAGGCU
miR-182214220m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-186109310991Ahsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
miR-215335391Ahsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-22411401146m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-2311371143m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-299-5p5385441Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-323113711431Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-329398404m8hsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-335105310591Ahsa-miR-335brainUCAAGAGCAAUAACGAAAAAUGU
miR-375105810641Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
miR-377630636m8hsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-49415521558m8hsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
miR-4958128181Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-539156515711Ahsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.