Found 139 literature records

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Entrez ID	Description
274	Missplicing of a brain-specific exon of Bin1 in human melanoma is sufficient to abolish tumor suppressor properties; ectopic WT Bin1 activates PCD in malignant but not normal melanocytes.
11108	"PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1. These results suggest a role for PFM1 in cell differentiation and tumor suppression, remarkably consistent with the known functions of the PR-domain family."
5325	"Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines."
7161	Allelic expression of the putative tumor suppressor gene p73 in human fetal tissues and tumor specimens.
23136	"Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas."
53353	"The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein."
5925	Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
55717	"Represents a candidate gene for the frequently proposed tumor suppressor gene in 10q25-26, which is involved in tumorigenesis of glial and other tumors showing frequent alterations in the distal 10q region."
199731	"Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins."
5728	Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.
5728	Primary malignant lymphoma of the brain: analysis of MMAC1 (PTEN) tumor suppressor gene.
7982	The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system
4763	probably does not have a role as tumor suppressor in sporadic pilocytic astrocytomas
4771	Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.
7249	Polycystic kidney results from a loss of the tuberous sclerosis 2 tumor suppressor gene during development.
7157	Data show that activated protein C directly prevents apoptosis in hypoxic human brain endothelium through transcriptionally dependent inhibition of tumor suppressor protein p53.
672	Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation.
8577	This protein may behave as a tumor suppressor gene in brain cancers.
7490	Wilms' tumor suppressor is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease.
23087	"gene located on chromosome 8p21, a region implicated in leukemias and solid tumors; enforced expression inhibited cell growth, clonogenicity, and tumorigenicity; conceivable HLS5 is one of the tumor suppressor genes thought to reside at the 8p21 locus"
7490	BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1.
11186	Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.
11010	"RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer."
5728	the tumor suppressor PTEN has a profound effect on differentiation by affecting several pathways involved in nerve growth factor signaling
53353	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.
79893	LCRG1 is a novel gene localized to the tumor suppressor locus D17S800-D17S930 involved in laryngeal carcinoma.
324	Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity.
1029	Primary malignant lymphoma of the brain: frequent abnormalities and inactivation of p14 tumor suppressor gene.
23261	"Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene."
10395	"DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development."
11186	The tumor suppressor RASSF1A in human carcinogenesis: an update.
9076	"This review summarizes the role of claudins in cancer and points out that claudin 1 (CLDN1) may support tumor suppressive functions in tissues such as the brain, where dramatic loss of CLDN1 expression has been demonstrated in glioblastoma multiforme."
324	This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP).
2189	"Finally, five novel minimally deleted regions were identified in a subset of tumors, containing putative candidate tumor suppressor genes (TOPORS, FANCG, RAD51, TP53BP1, and BIK) that could have a role in gliomagenesis."
4763	A conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling together with inactivation of p53 induce malignant astrocytoma.
7157	Inactivation of p53 and a conditional allele of the NF1 tumor suppressor that negatively regulates Ras signaling induce malignant astrocytoma.
64101	LRRC4 gene might be involved in tumor suppression by restraining DNA synthesis and nucleoli organizer regions-associated proteins.
22933	"the absence of SIRT2, a potential tumor suppressor, could play a key role in the regulation of the cell-cycle within a multistep pathway that leads to full cellular transformation and, finally, the development of cellular malignancy"
199731	"Cell adhesion and prostate tumor-suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4"
23136	The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
1031	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
5727	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
7157	The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
84707	Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
57509	"Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP."
7248	"According to Knudson's two-hit model of tumorigenesis, second-hit mutation and resulting loss of heterozygosity of a tumor suppressor gene (tsc1 and tsc2) is necessary for tumor formation"
7249	"According to Knudson's two-hit model of tumorigenesis, second-hit mutation and resulting loss of heterozygosity of a tumor suppressor gene (tsc1 and tsc2) is necessary for tumor formation"
253738	Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.
4601	Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma.
5728	Presenilins regulate the cellular level of the tumor suppressor PTEN.

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