Found 148 literature records

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Entrez ID	Description
135138	"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
5071	"candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm"
11186	[The RASSF1 (Ras association domain family protein 1) gene. Category: tumor suppressor gene].
672	"BRCA1 affects lipogenesis through binding to P-ACCA, suggesting a new mechanism by which BRCA1 may exert a tumor suppressor function"
5728	[Pathogenic role of PTEN tumor suppressor gene in ovarian cancer associated to endometriosis].
1316	E-cadherin pathway is a novel and functionally important mediator by which changes in Kruppel-like KLF6 tumor suppressor can directly alter ovarian tumor invasion and metastasis.
9940	Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer.
6196	"RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer."
672	BRCA1 is a tumor suppressor gene and is known to be responsible for breast cancer and breast-ovarian cancers running in families.
672	distinct single nucleotide changes in the BRCT domain of BRCA1 affect binding of this protein to the tumor suppressor p53
7157	distinct single nucleotide changes in the BRCT domain of BRCA1 affect binding of this protein to the tumor suppressor p53
1630	Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer.
10395	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
90627	Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.
11145	Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells.
54756	Inhibitory effect of hSef on cell proliferation combined with consistent downregulation in human carcinoma indicates a tumor suppressor-like role for Sef.
4216	"In this review, the role of MKK4 in cancer development appears complex, as some studies support a pro-oncogenic role for MKK4, while others suggest it may have tumor suppressor functions."
1490	Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
6794	Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).
90480	"NAC-1 contributes to tumor growth and survival by at least inhibiting Gadd45GIP1 expression, which has a tumor suppressor effect in cancer cells."
51741	Wwox hypomorphs had an increased incidence of B-cell lymphomas supports a role of Wwox as a tumor suppressor
11009	"MDA-7/IL-24, a novel tumor suppressor/cytokine is ubiquitinated and regulated by the ubiquitin-proteasome system, and inhibition of MDA-7/IL-24 degradation enhances the antitumor activity."
580	Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
11186	Adiposity and age are statistically related to enhanced RASSF1A tumor suppressor gene promoter methylation in normal autopsy kidney tissue.
27429	A significant downregulation of HtrA2 transcription is found in the group of borderline tumors of the ovary; HtrA2 may function as a tumor suppressor.
94031	In ovarian cancer there is a dramatic decrease of HtrA3 mRNA and protein levels in all ovarian tumor groups; HtrA3 may function as a tumor suppressor.
5654	There is a significant decrease in HtrA1 mRNA in malignant ovarian tumors compared to benign; HtrA1 may function as a tumor suppressor.
5178	Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation.
9077	Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation.
580	"The remarkable similarities between the mammary carcinomas of Bard1-, Brca1-, and Bard1/Brca1-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1/BARD1 heterodimer."
672	"The remarkable similarities between the mammary carcinomas of Bard1-, Brca1-, and Bard1/Brca1-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1/BARD1 heterodimer."
5934	Characterization of alterations of Rb2/p130 tumor suppressor in all-trans-retinoic acid resistant SK-OV3 ovarian carcinoma cells.
3488	IGFBP-5 expression prevented tumor growth and inhibited tumor vascularity in a xenograft model of human ovarian cancer. These results are the first evidence showing that IGFBP-5 plays a role as tumor suppressor by inhibiting angiogenesis
56849	"A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation."
26038	study demonstrated the existence of somatic mutations and methylation of CHD5 in primary epithelial ovarian cancers; CHD5 may play a role as a tumor suppressor gene in ovarian cancer
9077	The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
3732	"Tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation."
8821	"INPP4B has been identified as a tumor suppressor. Loss of heterozygosity (LOH) is found at the INPP4B locus in basal-like breast cancers, as well as in a significant fraction of ovarian cancers."
3685	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
3690	This study shows that alpha(v)beta(3)-integrin expression on tumor cells actually slows tumor progression and acts as a tumor suppressor.
51741	"WWOX acts as an ovarian tumor suppressor by modulating the interaction between tumor cells and the extracellular matrix, decreasing integrin activity and adhesion of tumor cells to fibronectin."
56849	"TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway."
114907	"The novel tumor suppressor FBXO32 is epigenetically silenced in ovarian cancer cell lines with disrupted TGF-beta/SMAD4 signaling, and FBXO32 methylation status predicts survival in patients with ovarian cancer."
23189	"KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia."
26136	TES gene functions as a tumor suppressor gene and is frequently silenced by hypermethylation and loss of heterozygosity in ovarian cancers.
78986	DUSP26 may function as a tumour suppressor in particular cancers.
675	Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells.
83719	"Findings point to YPEL3 being a novel tumor suppressor, which upon induction triggers a permanent growth arrest in human tumor and normal cells."
11145	role of PKC isoenzymes in PP2A and HRSL3(H-REV107-1) tumor suppressor-dependent cell death induction in ovarian carcinoma cell line; verified contribution to PP2A- and HRLS3-dependent apoptosis for PKCzeta suggesting a proapoptotic function of this kinase
672	Presymptomatic breast cancer in Egypt: role of BRCA1 and BRCA2 tumor suppressor genes mutations detection.

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