Found 616 literature records

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Entrez ID	Description
11186	The high incidence of 3p loss and RASSF1A promoter hypermethylation detected may have implications for this tumor suppressor gene in the malignant progression of cholangiocarcinoma.
2296	FOXC1 functions as a tumor suppressor through TGF-beta1 mediated signals.
6422	These results indicate that the human secreted frizzled-related protein (hsFRP) gene probably functions as a tumor suppressor in normal cervical epithelium and down-regulation of hsFRP contributes to development of cervical cancer.
7184	GRP94-elicited tumor suppression can occur independent of the GRP94 tissue of origin and suggest a primary role for GRP4 natural adjuvant function in antitumor immune responses.
11009	study demonstrate that expression of the MDA-7 tumor suppressor can negatively regulate iNOS expression in malignant melanoma cell lines
10395	"Genomic deletion of DLC-1 was observed in 40% of breast tumors, whereas reduced levels of DLC-1 mRNA were seen in 70% of breast, 70% of colon, 50% of prostate tumor cell lines.DLC-1 gene plays a role in breast cancer by acting as a tumor suppressor gene"
3814	Tumor suppressor role of KiSS-1 in bladder cancer: loss of KiSS-1 expression is associated with bladder cancer progression and clinical outcome.
2706	The expression of the tumor suppressor gene connexin 26 is not mediated by methylation in human esophageal cancer cells.
6595	This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
6597	This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
4851	Notch1 functions as a tumor suppressor in mouse skin.
665	"Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer."
9353	SLIT2 is an excellent candidate tumor suppressor gene for colorectal cancer.
7157	"EGR1 as a major regulator of cell senescence and previously undescribed upstream ""gatekeeper"" of the p53 tumor suppressor pathway."
283518	the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene
11186	Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.
83593	Nore1 is a member of a family of Ras effector/tumor suppressors that includes RASSF1
5728	Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas.
7249	Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma is associated with loss of Tsc-2 tumor suppressor gene.
1848	Results show that DUSP6 exerts apparent tumor-suppressive effects in vitro and suggest that DUSP6 is a strong candidate tumor suppressor gene at 12q22 locus.
11186	"Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells."
5728	Data suggest that PTEN tumor suppressor gene malfunction seems to be involved in metastasing capacity of hepatocellular carcinoma.
23328	tumor suppressor gene possibly involved in tumorigenesis of breast and other solid cancers
4221	Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.
10395	"DNA variants of DLC-1, a candidate tumor suppressor gene in human hepatocellular carcinoma."
11186	RASSF1 is a putative tumor suppressor in non-small cell lung cancer
51364	BLU may be one of the critical tumor suppressor genes on chromosome 3p21.3 involved in the development of nasopharyngeal carcinoma
10395	Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.
160728	"SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers."
7490	Expression of Wilms' tumor suppressor in the liver with cirrhosis: relation to hepatocyte nuclear factor 4 and hepatocellular function.
4221	Multiple tumor suppressor pathways negatively regulate telomerase.
11186	"Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma."
2272	"Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma."
5915	"Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma."
7428	"Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma."
5629	PROX1 gene corresponds to that of a candidate tumor-suppressor gene.
2272	"exogenous expression of FHIT in Panc-1 cells affects genes regulating cell cycle arrest and apoptosis, and these molecular changes may contribute to the tumor suppressor activity of the FHIT gene"
11009	Tumor suppressor MDA-7/IL-24 selectively inhibits vascular smooth muscle cell growth and migration.
11186	The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
23705	The results support the hypothesis that TSLC1 is a tumor suppressor of NSCLC and also suggest that preserved integrity of TSLC1 may contribute to less invasive phenotypes of lepidic growth tumor cells.
23705	Clinical implication and prognostic significance of the tumor suppressor TSLC1 gene detected in adenocarcinoma of the lung.
27113	"PUMA suppresses tumor cell growth in head/neck cancer, but it does not appear to be a direct target of inactivation in head and neck tumorigenesis."
838	Caspase-5 might be a suppressor gene of highly metastatic potential in lung cancer
23705	"Lung tumor suppressor gene,TSLC1, associates with MPP3, a human homologue of Drosophila tumor suppressor Dlg."
4013	The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
1647	"GADD45 is an important mediator for the tumor-suppressing activity of 1,25-dihydroxyvitamin D3 in human ovarian cancer cells"
5728	Expression of the tumor suppressor gene PTEN is not altered in the progression of ovarian carcinomas and does not correlate with p27Kip1 expression.
4601	These findings support MXI1 as a putative tumor suppressor gene involved in conventional melanoma progression.
7249	Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.
54739	"Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas."

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