Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44018958HTLV-1ENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB09016
Drug NameButriptyline
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs6086881; 3816971; 9537821
CitationsRichelson E, Nelson A: Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. J Pharmacol Exp Ther. 1984 Jul;230(1):94-102.@@Wander TJ, Nelson A, Okazaki H, Richelson E: Antagonism by antidepressants of serotonin S1 and S2 receptors of normal human brain in vitro. Eur J Pharmacol. 1986 Dec 16;132(2-3):115-21.@@Tatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.
GroupsApproved; Withdrawn
Direct ClassificationDibenzocycloheptenes
SMILES
Pathways
PharmGKB
ChEMBLCHEMBL2110816