Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44018958HTLV-1ENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB09128
Drug NameBrexpiprazole
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs26913177; 29955525; 26310190
CitationsDas S, Barnwal P, Winston A B, Mondal S, Saha I: Brexpiprazole: so far so good. Ther Adv Psychopharmacol. 2016 Feb;6(1):39-54. doi: 10.1177/2045125315614739.@@Diefenderfer LA, Iuppa C: Brexpiprazole: A review of a new treatment option for schizophrenia and major depressive disorder. Ment Health Clin. 2018 Mar 23;7(5):207-212. doi: 10.9740/mhc.2017.09.207. eCollection 2017 Sep.@@Greig SL: Brexpiprazole: First Global Approval. Drugs. 2015 Sep;75(14):1687-97. doi: 10.1007/s40265-015-0462-2.
GroupsApproved; Investigational
Direct ClassificationN-arylpiperazines
SMILESO=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1
Pathways
PharmGKBPA166160053
ChEMBLCHEMBL2105760