Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44018958HTLV-1ENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB01224
Drug NameQuetiapine
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs11132243; 17848919
CitationsRichelson E, Souder T: Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci. 2000 Nov 24;68(1):29-39.@@Nasrallah HA: Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol Psychiatry. 2008 Jan;13(1):27-35. Epub 2007 Sep 11.
GroupsApproved
Direct ClassificationDibenzothiazepines
SMILESOCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12
PathwaysQuetiapine H1-Antihistamine Action
PharmGKBPA451201
ChEMBLCHEMBL716