Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44018958HTLV-1ENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB08800
Drug NameChloropyramine
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs19610651
CitationsKurenova EV, Hunt DL, He D, Magis AT, Ostrov DA, Cance WG: Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo. J Med Chem. 2009 Aug 13;52(15):4716-24. doi: 10.1021/jm900159g.
GroupsExperimental
Direct Classification2-benzylaminopyridines
SMILESCN(C)CCN(CC1=CC=C(Cl)C=C1)C1=CC=CC=N1
PathwaysChloropyramine H1-Antihistamine Action
PharmGKBPA165958419
ChEMBLCHEMBL1194287