Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44018958HTLV-1ENSG00000196639.7protein_codingHRH1NoNo3269P35367
TCGA Plot Options
Drug Information
GeneHRH1
DrugBank IDDB00420
Drug NamePromazine
Target IDBE0000442
UniProt IDP35367
Regulation Typeantagonist
PubMed IDs2899826; 19110200
CitationsHals PA, Hall H, Dahl SG: Muscarinic cholinergic and histamine H1 receptor binding of phenothiazine drug metabolites. Life Sci. 1988;43(5):405-12.@@Kim DH, Maneen MJ, Stahl SM: Building a better antipsychotic: receptor targets for the treatment of multiple symptom dimensions of schizophrenia. Neurotherapeutics. 2009 Jan;6(1):78-85. doi: 10.1016/j.nurt.2008.10.020.
GroupsApproved; Vet_approved
Direct ClassificationPhenothiazines
SMILESCN(C)CCCN1C2=CC=CC=C2SC2=CC=CC=C12
Pathways
PharmGKBPA451126
ChEMBLCHEMBL564