Gene Page: BAIAP2

Summary
GeneID  10458
Symbol  BAIAP2
Synonyms  BAP2|IRSP53
Description  BAI1-associated protein 2
See related  HGNC:947|MIM:605475|Ensembl:ENSG00000175866|HPRD:05686|
Locus tag  -
Gene type  protein-coding
Map location  17q25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COPB10.950.96
XRCC50.950.94
ARF40.950.95
POLR2B0.940.93
HSF20.940.94
MATR30.940.93
RFWD20.940.93
CCT6A0.940.92
PTBP20.940.93
CSE1L0.940.93
Top 10 negatively co-expressed genes
MT-CO2-0.75-0.88
AF347015.33-0.74-0.88
MT-CYB-0.74-0.88
AF347015.31-0.74-0.86
AF347015.8-0.73-0.90
AF347015.27-0.73-0.85
AF347015.15-0.72-0.88
HLA-F-0.71-0.78
AIFM3-0.71-0.78
AF347015.26-0.70-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008022protein C-terminus bindingTAS10343108 
GO:0008093cytoskeletal adaptor activityTAS10343108 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007409axonogenesisTASneuron, axon, neurite (GO term level: 12)10343108 
GO:0046847filopodium formationIEAaxon (GO term level: 10)-
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0007165signal transductionIEA-
GO:0008286insulin receptor signaling pathwayTAS10343108 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0005737cytoplasmTAS10343108 
GO:0005886plasma membraneTAS10343108 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATN1B37 | D12S755E | DRPLA | NODatrophin 1-HPRD,BioGRID10332026 
BAI1FLJ41988brain-specific angiogenesis inhibitor 1-HPRD,BioGRID10343108 
C14orf1ERG28 | NET51chromosome 14 open reading frame 1Two-hybridBioGRID16169070 
CDC42CDC42Hs | G25Kcell division cycle 42 (GTP binding protein, 25kDa)-HPRD,BioGRID11696321 
DIAPH1DFNA1 | DIA1 | DRF1 | FLJ25265 | LFHL1 | hDIA1diaphanous homolog 1 (Drosophila)-HPRD10814512 
ENAHENA | MENA | NDPP1enabled homolog (Drosophila)Reconstituted ComplexBioGRID11696321 
EPS8-epidermal growth factor receptor pathway substrate 8-HPRD,BioGRID15289329 
LIN7ALIN-7A | LIN7 | MALS-1 | MGC148143 | TIP-33 | VELI1lin-7 homolog A (C. elegans)-HPRD14596909 
LIN7BLIN-7B | MALS-2 | MALS2 | VELI2lin-7 homolog B (C. elegans)-HPRD14596909 
NCKIPSDAF3P21 | DIP | DIP1 | MGC23891 | ORF1 | SPIN90 | WASLBP | WISHNCK interacting protein with SH3 domainTwo-hybridBioGRID16189514 
PAK1MGC130000 | MGC130001 | PAKalphap21 protein (Cdc42/Rac)-activated kinase 1Reconstituted ComplexBioGRID11130076 
RAC1MGC111543 | MIG5 | TC-25 | p21-Rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-HPRD,BioGRID11130076 |12054568 
SHANK1SPANK-1 | SSTRIP | synamonSH3 and multiple ankyrin repeat domains 1-HPRD,BioGRID12504591 
SHANK2CORTBP1 | CTTNBP1 | ProSAP1 | SHANK | SPANK-3SH3 and multiple ankyrin repeat domains 2-HPRD12504591 
WASF1FLJ31482 | KIAA0269 | SCAR1 | WAVE | WAVE1WAS protein family, member 1Far Western
Reconstituted Complex
Two-hybrid		BioGRID11130076 
WASF2SCAR2 | WAVE2 | dJ393P12.2WAS protein family, member 2-HPRD,BioGRID11130076 
YWHAG14-3-3GAMMAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptideAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ADHERENS_JUNCTION 7553All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
BIOCARTA_RHO_PATHWAY 3223All SZGR genes in this pathway
PID_CDC42_PATHWAY 7051All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY 10578All SZGR genes in this pathway
PID_PDGFRB_PATHWAY 129103All SZGR genes in this pathway
PID_RAC1_PATHWAY 5437All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_DN 260143All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN 153100All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP 146104All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP 181108All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN 3123All SZGR genes in this pathway
RICKMAN_METASTASIS_DN 261155All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT 6637All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON 335181All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 6733All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
MCCLUNG_COCAINE_REWARD_5D 7962All SZGR genes in this pathway
DELASERNA_MYOD_TARGETS_DN 5742All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_DN 12386All SZGR genes in this pathway
KIM_GASTRIC_CANCER_CHEMOSENSITIVITY 10364All SZGR genes in this pathway
VARELA_ZMPSTE24_TARGETS_UP 4030All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
OUYANG_PROSTATE_CANCER_PROGRESSION_DN 2116All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_DN 2917All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_DN 11376All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G1_S 14776All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-149338344m8hsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-181136913761A,m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-29171177m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-331134513521A,m8hsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-4958793m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
miR-496140514111Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-504162168m8hsa-miR-504AGACCCUGGUCUGCACUCUAU
miR-97917971Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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