Gene Page: SDC1

Summary
GeneID  6382
Symbol  SDC1
Synonyms  CD138|SDC|SYND1|syndecan
Description  syndecan 1
See related  HGNC:10658|MIM:186355|Ensembl:ENSG00000115884|HPRD:01718|
Locus tag  -
Gene type  protein-coding
Map location  2p24.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.008 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NOL110.960.96
SMARCE10.960.96
CBX30.960.95
FAM76B0.960.94
HNRNPH10.950.95
SMC30.950.93
CEP570.950.95
COIL0.950.95
SNW10.950.96
DHX90.950.95
Top 10 negatively co-expressed genes
HLA-F-0.73-0.84
AIFM3-0.71-0.81
TSC22D4-0.71-0.85
AF347015.31-0.70-0.88
C5orf53-0.70-0.75
FXYD1-0.70-0.90
IFI27-0.70-0.90
MT-CO2-0.69-0.89
PTH1R-0.69-0.78
ALDOC-0.69-0.75
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008092cytoskeletal protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0009986cell surfaceIEA-
GO:0005887integral to plasma membraneTAS2324102 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CASKCAGH39 | CMG | FLJ22219 | FLJ31914 | LIN2 | MICPCH | TNRC8calcium/calmodulin-dependent serine protein kinase (MAGUK family)-HPRD,BioGRID9660868 
CCL5D17S136E | MGC17164 | RANTES | SCYA5 | SISd | TCP228chemokine (C-C motif) ligand 5-HPRD,BioGRID14637022 
CTSGCG | MGC23078cathepsin G-HPRD,BioGRID9565572 
ELA2GE | HLE | HNE | NE | PMN-Eelastase 2, neutrophil-HPRD9565572 
FGF2BFGF | FGFB | HBGF-2fibroblast growth factor 2 (basic)Co-purificationBioGRID16982797 
HGFF-TCF | HGFB | HPTA | SFhepatocyte growth factor (hepapoietin A; scatter factor)-HPRD,BioGRID11830493 
IGFBP7FSTL2 | IGFBP-7 | IGFBP-7v | IGFBPRP1 | MAC25 | PSFinsulin-like growth factor binding protein 7-HPRD14521955 
IL8CXCL8 | GCP-1 | GCP1 | LECT | LUCT | LYNAP | MDNCF | MONAP | NAF | NAP-1 | NAP1interleukin 8-HPRD,BioGRID12902511 
LACRTMGC71934lacritinCo-purificationBioGRID16982797 
MDKFLJ27379 | MK | NEGF2midkine (neurite growth-promoting factor 2)-HPRD9089390 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophin-HPRD7592855 
Reconstituted ComplexBioGRID8175719 
SDCBPMDA-9 | ST1 | SYCL | TACIP18syndecan binding protein (syntenin)-HPRD,BioGRID11179419 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ECM_RECEPTOR_INTERACTION 8453All SZGR genes in this pathway
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
PID_INTEGRIN3_PATHWAY 4325All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY 7553All SZGR genes in this pathway
PID_SYNDECAN_1_PATHWAY 4629All SZGR genes in this pathway
PID_INTEGRIN5_PATHWAY 179All SZGR genes in this pathway
REACTOME_HS_GAG_DEGRADATION 2015All SZGR genes in this pathway
REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM 4933All SZGR genes in this pathway
REACTOME_HS_GAG_BIOSYNTHESIS 3117All SZGR genes in this pathway
REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM 5233All SZGR genes in this pathway
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 11169All SZGR genes in this pathway
REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS 2517All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT 4637All SZGR genes in this pathway
REACTOME_LIPOPROTEIN_METABOLISM 2824All SZGR genes in this pathway
REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT 1615All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
FRASOR_TAMOXIFEN_RESPONSE_UP 5136All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN 182111All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_UP 13582All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_DN 260143All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
CASTELLANO_NRAS_TARGETS_UP 6841All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP 170114All SZGR genes in this pathway
TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP 75All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_DN 7954All SZGR genes in this pathway
MCBRYAN_TERMINAL_END_BUD_UP 1212All SZGR genes in this pathway
LUND_SILENCED_BY_METHYLATION 1612All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN 5142All SZGR genes in this pathway
HASINA_NOL7_TARGETS_DN 139All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
INGRAM_SHH_TARGETS_DN 6441All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN 382224All SZGR genes in this pathway
RICKMAN_METASTASIS_DN 261155All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP 283177All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP 7151All SZGR genes in this pathway
IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_UP 2814All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL 254164All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
GERHOLD_ADIPOGENESIS_DN 6444All SZGR genes in this pathway
BURTON_ADIPOGENESIS_2 7252All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C7 6844All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_UP 8152All SZGR genes in this pathway
BILD_HRAS_ONCOGENIC_SIGNATURE 261166All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE 7750All SZGR genes in this pathway
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN 3623All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_DN 1816All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_UP 5429All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
GU_PDEF_TARGETS_UP 7149All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
CHANG_CYCLING_GENES 14883All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN 204114All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G1_S 14776All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
VANOEVELEN_MYOGENESIS_SIN3A_TARGETS 220133All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway
NABA_ECM_AFFILIATED 17189All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-107507571A,m8hsa-miR-10aUACCCUGUAGAUCCGAAUUUGUG
hsa-miR-10bUACCCUGUAGAACCGAAUUUGU
miR-195105171A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2811181124m8hsa-miR-28brainAAGGAGCUCACAGUCUAUUGAG
miR-9116711731Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-93.hd/291-3p/294/295/302/372/373/5204034101A,m8hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.