Gene Page: WNK1

Summary
GeneID  65125
Symbol  WNK1
Synonyms  KDP|KIAA0344|PHA2C|PRKWNK1|PSK
Description  WNK lysine deficient protein kinase 1
See related  HGNC:14540|MIM:605232|Ensembl:ENSG00000060237|HPRD:05570|
Locus tag  -
Gene type  protein-coding
Map location  12p13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 2.562 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003674molecular_functionND-
GO:0005515protein bindingIPI15350218 
GO:0005524ATP bindingIDA10660600 
GO:0004860protein kinase inhibitor activityIEA-
GO:0004674protein serine/threonine kinase activityIDA10660600 
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIDA10660600 
GO:0007243protein kinase cascadeIDA10660600 
GO:0008150biological_processND-
GO:0006811ion transportISS-
GO:0050794regulation of cellular processISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005625soluble fractionIEA-
GO:0005737cytoplasmIDA10660600 
GO:0005737cytoplasmNAS-
GO:0042598vesicular fractionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
E2F3DKFZp686C18211 | E2F-3 | KIAA0075 | MGC104598E2F transcription factor 3Two-hybridBioGRID12748276 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP 194112All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_DN 13797All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
PARK_HSC_MARKERS 4431All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_DN 14588All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
MCCLUNG_COCAIN_REWARD_4WK 7547All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP 196137All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN 3729All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP 7451All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP 181112All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 6850All SZGR genes in this pathway
GABRIELY_MIR21_TARGETS 289187All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE 293119All SZGR genes in this pathway


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