Gene Page: GOSR1

Summary
GeneID  9527
Symbol  GOSR1
Synonyms  GOLIM2|GOS-28|GOS28|GOS28/P28|GS28|P28
Description  golgi SNAP receptor complex member 1
See related  HGNC:4430|MIM:604026|Ensembl:ENSG00000108587|
Locus tag  -
Gene type  protein-coding
Map location  17q11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STIM10.840.88
AC105206.10.840.91
MAP2K10.830.89
NPTN0.830.88
RP5-1187M17.10.830.88
ACTN10.830.83
RASGEF1A0.830.89
C2orf550.830.82
SLC35F30.820.87
NCDN0.820.83
Top 10 negatively co-expressed genes
BCL7C-0.43-0.53
HEBP2-0.40-0.55
KIAA1949-0.40-0.28
TUBB2B-0.39-0.39
TRAF4-0.39-0.43
SH2B2-0.38-0.41
FABP7-0.38-0.47
AF186192.1-0.38-0.27
RBMX2-0.38-0.42
FADS2-0.38-0.32
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005484SNAP receptor activityIDA15215310 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006886intracellular protein transportIEA-
GO:0006891intra-Golgi vesicle-mediated transportTAS8636227 
GO:0016192vesicle-mediated transportIEA-
GO:0042147retrograde transport, endosome to GolgiIDA15215310 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0031201SNARE complexTASneuron, Synap (GO term level: 6)15215310 
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIDA15215310 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BET1DKFZp781C0425 | HBET1blocked early in transport 1 homolog (S. cerevisiae)Affinity Capture-WesternBioGRID11927603 
BET1LBET1L1 | GOLIM3 | GS15 | HSPC197blocked early in transport 1 homolog (S. cerevisiae)-likeAffinity Capture-WesternBioGRID11927603 |12388752 
EBI3IL27BEpstein-Barr virus induced 3-HPRD,BioGRID12121660 
GABARAPL2ATG8 | GATE-16 | GATE16 | GEF-2 | GEF2GABA(A) receptor-associated protein-like 2-HPRD10747018 
IL27RACRL1 | IL27R | TCCR | WSX1 | zcytor1interleukin 27 receptor, alphaAffinity Capture-WesternBioGRID12121660 
NAPASNAPAN-ethylmaleimide-sensitive factor attachment protein, alpha-HPRD9325254 
NSFSKD2N-ethylmaleimide-sensitive factor-HPRD8636227 |9325254 
SNAP25FLJ23079 | RIC-4 | RIC4 | SEC9 | SNAP | SNAP-25 | bA416N4.2 | dJ1068F16.2synaptosomal-associated protein, 25kDaReconstituted ComplexBioGRID9325254 
STX5SED5 | STX5Asyntaxin 5-HPRD,BioGRID9094723 
USO1P115 | TAP | VDPUSO1 homolog, vesicle docking protein (yeast)Co-purification
Reconstituted Complex		BioGRID11927603 
YKT6-YKT6 v-SNARE homolog (S. cerevisiae)Affinity Capture-WesternBioGRID11927603 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 3825All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN 7038All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP 181108All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON 13378All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
NOUZOVA_TRETINOIN_AND_H4_ACETYLATION 14385All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_UP 7456All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_UP 15692All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-17-5p/20/93.mr/106/519.d42854291m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-93723781Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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