Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 29 literature records

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Entrez IDDescription
27086The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
864"Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor."
1500roles of p120 as a tumor suppressor or metastasis promoter are discussed (review)
219699UNC5H may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
8633may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
90249may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
137075"characterization of CLDN23 gene, a candidate tumor suppressor gene implicated in intestinal-type gastric cancer"
1002CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis
26136TES acts as a tumor suppressor in an established model of carcinogen-induced gastric cancer
864The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.
822CapG is a new tumor suppressor gene involved in the tumorigenic progression of certain cancers
2272"Nit1 and Fhit share tumor suppressor signaling pathways, while localization of the NIT1 gene at a stable chromosome site explains the paucity of gene alterations and in frequent loss of expression of the NIT1 gene in human malignancies."
3486"Results showed that IGFBP-3 methylation played an important role in the silencing of its expression, suggesting that IGFBP-3 may act as a tumor suppressor gene in several human cancers examined."
2272"absence or poor expression of the Fhit protein in anal cancers suggests a role for this tumor suppressor gene product, as a risk factor, in the onset of this cancer, as reported before for other gastrointestinal tumors"
1029"ISOC2 is a novel functional protein, which is able to bind and co-localize with a tumor suppressor gene p16(INK4a)."
8379"The MAD1 gene could be a candidate tumor suppressor gene, and the down-regulation of MAD1 expression may contribute to tumorigenesis in human stomach."
55294FBXW7/hCDC4 is a general tumor suppressor in human cancer.
57491These results therefore demonstrate that AHRR is a putative new tumor suppressor gene in multiple types of human cancers.
27250mir-21 functions as an oncogene by a mechanism that involves translational repression of the tumor suppressor Pdcd4
7345Epigenetic inactivation of UCHL1 is common in primary hepatocellular carcinomas(HCCs) and other digestive tumors and appears to be functional tumor suppressor involved in tumorigenesis of HCCs and other digestive cancers.
2272Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients.
1015Targeting CDH17 in HCC can inhibit tumor growth and inactivate Wnt signaling pathway in concomitance with activation of tumor suppressor genes.[review]
84651ECRG2 is a novel member of the Kazal-type serine protease inhibitor family and may function as a tumor suppressor gene regulating the protease cascades during carcinogenesis and invasion of esophageal cancer.
11186Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
2272Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.
1500Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.
1036CDO1 as a novel tumor suppressor gene and a potentially valuable molecular marker for human cancer
2272Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
11145Growth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumors.

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