Found 616 literature records

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Entrez ID	Description
7980	TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
6598	Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.
3621	The tumor suppressor ING1 contributes to epigenetic control of cellular senescence.
1029	Alterations in the tumor suppressor gene p16(INK4A) are associated with aggressive behavior of penile carcinomas.
7157	Alterations in the tumor suppressor gene p16(INK4A) are associated with aggressive behavior of penile carcinomas.
5925	The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression.
8821	INPP4B functions as a tumor suppressor by negatively regulating normal and malignant mammary epithelial cell proliferation through regulation of the PI3K/Akt signaling pathway
1029	ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice
7157	"Mouse double minute 2 (Mdm2) gene links genotoxic stress and metabolism to tumor suppressor, p53. (Review)"
10395	A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors.
57447	Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
6597	MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4.
8125	MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4.
5079	tumor suppressor gene PAX5 is inactivated by promoter methylation in liver cancer. PAX5 contributes to suppression of hepatocarcinogenesis by inhibiting cell proliferation and inducing cell apoptosis through direct regulating p53 signaling pathway.
8099	miR-21 downregulates the tumor suppressor P12 CDK2AP1 and stimulates cell proliferation and invasion.
7545	"ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer."
406988	"EMT was epigenetically driven by chromatin remodeling through H3K27me3 enrichment and later by ensuing DNA methylation to sustain silencing of tumor-suppressive microRNAs (miRNA), miR-200b, miR-200c, and miR-205."
619554	miR-486 may function as a novel tumor-suppressor miRNA in gastric cancer. Its antioncogenic activity may involve the direct targeting and inhibition of OLFM4.
8856	"These results demonstrate a novel and unsuspected role for steroid and xenobiotic receptor (SXR) signaling in the B-1 cell compartment, establish SXR as a tumor suppressor in B-1 cells"
5728	role of post-translational modification of PTEN in host tumor suppressor functions; possibility of antineoplastic therapy using drugs that regulate post-translational modification of PTEN [REVIEW]
1029	"Cancerous tissues from 30 patients with HPSCC were examined for LOH in 4 tumor suppressor genes (TSGs) (p16, Rb, E-cadherin, and p53) at loci 9p21, 13q21, 6q22, and 17p13, respectively, using microsatellite markers amplified by polymerase chain reaction."
5925	"Cancerous tissues from 30 patients with HPSCC were examined for LOH in 4 tumor suppressor genes (TSGs) (p16, Rb, E-cadherin, and p53) at loci 9p21, 13q21, 6q22, and 17p13, respectively, using microsatellite markers amplified by polymerase chain reaction."
7157	"Cancerous tissues from 30 patients with HPSCC were examined for LOH in 4 tumor suppressor genes (TSGs) (p16, Rb, E-cadherin, and p53) at loci 9p21, 13q21, 6q22, and 17p13, respectively, using microsatellite markers amplified by polymerase chain reaction."
999	"Cancerous tissues from 30 patients with HPSCC were examined for LOH in 4 tumor suppressor genes (TSGs) (p16, Rb, E-cadherin, and p53) at loci 9p21, 13q21, 6q22, and 17p13, respectively, using microsatellite markers amplified by polymerase chain reaction."
9365	our results suggest that klotho is inactivated through promoter hypermethylation and potentially functions as a tumor suppressor gene in colorectal cancer
7048	TGF-? acts as a suppressor of primary tumor initiation but has been implicated as a promoter of the later malignant stages.
3090	Identification of novel subregions of LOH in gastric cancer and analysis of the HIC1 and TOB1 tumor suppressor genes in these subregions.
4089	"Aberrant TGF??/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer."
139285	The constellation of anomalies in Wtx null mice suggests that this tumor suppressor broadly regulates mesenchymal progenitor cells in multiple tissues.
27122	data demonstrate that MYCN-regulated miRNAs are able to modulate the expression of the tumor suppressor DKK3 in neuroblastoma
6416	Analysis of the mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer.
659	BMPR2 has tumor-suppressive function in mammary epithelia and microenvironment and that disruption can accelerate mammary carcinoma metastases.
23136	miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3.
26038	data suggest that CHD5 is a tumor suppressor gene that is epigenetically downregulated in laryngeal squamous cell carcinoma.
11334	Regulation of tumor suppressor gene FUS1 expression by the untranslated regions of mRNA in human lung cancer cells.
1002	CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma.
2272	Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
51741	Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
406935	miR-143 functions as a tumor suppressor in MLL-AF4 B-cell acute lymphoblastic leukemia.
285671	RNF180 is a novel potential tumor suppressor in gastric carcinogenesis.
4851	"identified mutations in FBXW7 and NOTCH in head and neck squamous cell carcinoma; nearly 40% of mutations in NOTCH1 predicted to truncate the gene product, suggesting NOTCH1 may function as tumor suppressor gene rather than oncogene in this tumor type"
1029	Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.
7157	Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.
27303	"a tumor suppression function for the human RBMS3 gene in esophageal squamous cell carcinoma, acting through c-Myc downregulation, with genetic loss of this gene contributing to poor outcomes in disease"
55164	study suggests that GRIM-1 (SHQ1) might act as a co-tumor suppressor in the prostate
407024	These findings suggest that miRNA-29b may play an important role in MM as a tumor suppressor.
54778	Arkadia enhances transforming growth factor-beta signaling responses and supports its tumor-suppressing properties in colorectal cancer.
2203	epigenetic inactivation of FBP1 is also common in human liver and colon cancer. FBP1 appears to be a functional tumor suppressor involved in the liver and colon carcinogenesis
3663	IRF5 is an important tumor suppressor that regulates multiple cellular processes involved in the conversion of normal mammary epithelial cells to tumor epithelial cells with metastatic potential.
22882	results demonstrate multiple mechanisms decreasing expression of tumor suppressor gene ZHX2 in Hodgkin lymphoma cell lines

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