Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 476 literature records
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Entrez ID
Description
5268
"The function of maspin as a tumor suppressor gene involved in tumor invasion, metastasis, and angiogenesis may not be limited to breast cancer."
4507
"Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line."
5325
"LOT1 (PLAGL1/ZAC1), the candidate tumor suppressor gene at chromosome 6q24-25, is epigenetically regulated in cancer."
55193
"cDNA cloning; the hPB1 gene is located on chromosome 3p21, where the tumor suppressor genes for breast, lung and kidney cancers have been mapped"
1500
roles of p120 as a tumor suppressor or metastasis promoter are discussed (review)
5268
"Maspin, a breast tumor suppressor gene is a valuable marker of the disease progression in breast neoplasms."
10395
"Genomic deletion of DLC-1 was observed in 40% of breast tumors, whereas reduced levels of DLC-1 mRNA were seen in 70% of breast, 70% of colon, 50% of prostate tumor cell lines.DLC-1 gene plays a role in breast cancer by acting as a tumor suppressor gene"
665
"Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer."
9353
SLIT2 is an excellent candidate tumor suppressor gene for colorectal cancer.
6598
"Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2."
10395
"Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers."
219699
UNC5H may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
8633
may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
90249
may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
5071
"Parkin, implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 in breast asnd ovarian cancers."
23328
tumor suppressor gene possibly involved in tumorigenesis of breast and other solid cancers
5655
Loss of expression of the putative tumor suppressor NES1 gene in biopsy-proven ductal carcinoma in situ predicts for invasive carcinoma at definitive surgery
10395
"DNA variants of DLC-1, a candidate tumor suppressor gene in human hepatocellular carcinoma."
9077
"Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers."
11186
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
4013
The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
9077
Loss of the expression of the tumor suppressor gene ARHI is associated with progression of breast cancer.
672
risks of breast and ovarian cancer were determined for Ashkenazi Jewish women with inherited mutations in the tumor suppressor genes BRCA1 and BRCA2
675
risks of breast and ovarian cancer were determined for Ashkenazi Jewish women with inherited mutations in the tumor suppressor genes BRCA1 and BRCA2
6294
"REVIEW: possibility that SAFB1 and SAFB2 are novel breast tumor suppressor genes, and how they might function in this role, are discussed"
9667
"REVIEW: possibility that SAFB1 and SAFB2 are novel breast tumor suppressor genes, and how they might function in this role, are discussed"
8065
"The chromosomal location of CUL-5 (11q 22-23) is associated with LOH in breast cancer, suggesting that CUL-5 may be a tumor suppressor."
7161
"p73 plays a tumor suppressor role in bladder cancer, and its inactivation occurs through an epigenetic mechanism, most probably involving protein degradation."
10395
DLC-1 plays a role in non-small cell lung carcinoma by acting as a bona fide new tumor suppressor gene.
7490
Inhibition of breast cancer cell growth by the Wilms' tumor suppressor WT1 is associated with a destabilization of beta-catenin.
51741
An opposing view on WWOX protein function as a tumor suppressor.
5268
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
1801
Ovca1 is a tumor suppressor that can modify p53-induced tumorigenesis and suggest that it acts as a positive regulator for cell cycle progression.
5216
tumor suppressor function of PFN1 requires a functional actin binding site
5371
Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
7490
Activation of the WT1 tumor suppressor gene promoter by Pea3.
3090
"Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1."
5071
Parkin is a tumor suppressor gene whose inactivation may play an important role in non-small cell lung cancer tumorigenesis
6416
Disruption of MKK4 signaling reveals its tumor suppressor role in embryonic stem cells.
5934
"pRb2/p130 overexpression is able to arrest cell growth in ovarian carcinoma cells, suggesting the putative role of pRb2/p130 as a tumor suppressor in this malignancy."
23136
Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation.
5728
Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells.
4087
"Differential gene expression of Smad2, a tumor suppressor gene, plays a significant role in the proliferation of breast cancer"
7071
"Differential gene expression of TIEG, a tumor suppressor gene, plays a significant role in the proliferation of breast cancer"
580
"differential gene expression of Bard1, a tumor suppressor gene, plays a significant role in the proliferation of breast cancer"
3659
"a novel tumor necrosis factor (ligand) superfamily, member 10-mediated tumor suppressor activity of interferon regulatory factor 1 and suggest a mechanistic basis for the synergistic antitumor activities of certain retinoids and interferons"
324
"The tumor suppressor gene, APC, is an independent prognostic parameter with poor outcome in breast cancer patients."
11186
"The tumor suppressor gene, RASSF1A, is an independent prognostic parameter with poor outcome in breast cancer patients."
2810
The present immunohistochemical study confirmed 14-3-3sigma as a tumor suppressor in breast carcinogenesis.
23136
DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.
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