Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 139 literature records

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Entrez IDDescription
5925Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context.
5925Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.
23405We conclude that Dicer1 functions as a haploinsufficient tumor suppressor. This finding has implications for cancer etiology and cancer therapy.
7799DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer.
286826These experiments provide the first direct genetic evidence for the role of LIN9 in development and mitotic gene regulation and they suggest that it may function as a haploinsufficient tumor suppressor.
1009Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death
23582It is proposed for the first time that Rad may promote carcinogenesis at least in part by inhibiting GCIP-mediated tumor suppression.
7799"Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation."
5925Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor.
5925The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.
5934The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.
7799Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.
1029The p16(INK4A) tumor suppressor regulates cellular oxidative stress.
1029p16 controls the cell cycle as tumor suppressor
5925Methylation of the retinoblastoma tumor suppressor by SMYD2.
554213"Data indicate that miR-449a is a miRNA component of the Rb pathway and its tumor suppressor-like effects, in part, depends on Rb status in prostate cancer cells."
5925"Data indicate that miR-449a is a miRNA component of the Rb pathway and its tumor suppressor-like effects, in part, depends on Rb status in prostate cancer cells."
693123"Enhanced NPM-retinoblastoma tumor suppressor protein (pRB) interaction, leading to the relief of the repressive pRB-E2F1 circuitry and the consequent transcriptional activation of E2F1 and several downstream DNA repair genes."
5925The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression.
5925miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor.
9046Mutational analysis of DOK2 tumor suppressor gene in acute leukemias.
26524"Results reveal a functional connection between the pRB and Hippo tumor suppressor pathways, and suggest that low levels of LATS2 may undermine the ability of pRB to induce a permanent cell cycle arrest in tumor cells."
5925"Results reveal a functional connection between the pRB and Hippo tumor suppressor pathways, and suggest that low levels of LATS2 may undermine the ability of pRB to induce a permanent cell cycle arrest in tumor cells."
1029Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.
7157Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.
5925The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway.
5925Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association with the proneural subtype.
2100"findings unveil a potential tumor-suppressor role of ERbeta in ovarian carcinogenesis, which could be of potential clinical relevance for the selection of the most appropriate treatment for patients"
1894miR-223 functions as a tumor suppresser in osteosarcoma and miR-223/Ect2/p21 signaling is an important pathway that regulates the osteosarcoma cell cycle progression and proliferaion
407008miR-223 functions as a tumor suppressor in osteosarcoma and miR-223/Ect2/p21 signaling is an important pathway that regulates the osteosarcoma cell cycle progression and proliferaion
5925Tumor suppressor gene expression during normal and pathologic myocardial growth.
5933Tumor suppressor gene expression during normal and pathologic myocardial growth.
7157Tumor suppressor gene expression during normal and pathologic myocardial growth.
6764"The tumor-suppressor gene locus ST5 (21), located proximal to HBB, had no LOH, suggesting that it is not involved in NSCLC pathogenesis."
1029Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.
7490Expression of the tumor suppressor gene WT1 in both human and mouse bone marrow.
5925Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.
5925"Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells."
7490Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition.


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