Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 81 literature records
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Entrez ID
Description
1029
Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
375
Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
1029
Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
1030
Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
8915
These data suggest that wild-type BCL10 may act as a tumor suppressor.
27086
The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
1029
p14(ARF) nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathways.
5728
Primary malignant lymphoma of the brain: analysis of MMAC1 (PTEN) tumor suppressor gene.
1029
Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
1030
Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
5728
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.
1029
ATM and the ARF-p53 tumor suppressor pathway may cooperate in the pathogenesis of diffuse large B-cell lymphoma
5934
Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: implications for disease pathogenesis.
7157
investigated whether Tat might alter p53 acetylation and p53-responsive transcription; results allude to mechanism where the HIV-1 trans-activator might impair tumor suppressor functions favoring establishment of neoplasia in AIDS
1027
deregulation of control mechanisms at G1/S transition by combination of high cyclin E levels in the absence of p27(Kip1) is sufficient to predispose mice to develop lymphoid malignancies and further support a role of p27(Kip1) as a tumor suppressor
5629
PROX1 gene corresponds to that of a candidate tumor-suppressor gene.
122953
c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene
5655
"The normal epithelial cell-specific 1 (NES1) gene, a candidate tumor suppressor gene on chromosome 19q13.3-4, is downregulated by hypermethylation in acute lymphoblastic leukemia."
1031
"p18INK4c may function as a tumor suppressor in Hodgkin lymphoma, and inactivation may contribute to cell cycle deregulation and defective terminal differentiation of the Reed-Sternberg cells."
7474
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue.
355
Tumor suppressor gene regions responsible for lymphomagenesis might not considerably differ due to the Fas gene status.
5371
Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
80198
studies demonstrate a critical role for the proper biallelic expression of the mammalian Mus81 in the maintenance of genomic integrity and tumor suppression
6091
Dutt1/Robo1 is a classic tumor suppressor gene requiring inactivation of both alleles to elicit lung tumorigenesis in these mice.
1029
Primary malignant lymphoma of the brain: frequent abnormalities and inactivation of p14 tumor suppressor gene.
5777
STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.
10912
Results show that GADD45G can act as a functional new-age tumor suppressor but being frequently inactivated epigenetically in multiple tumors.
3621
the suggested role of ing1 as a candidate tumor suppressor gene involved in control of DNA damage response.
9937
Snm1 is a tumor suppressor in mice that in addition has a role in immunity
639
identifies PRDM1 inactivation as a recurrent genetic defect in diffuse large B-cell lymphomas cells and establishes PRDM1 as a potential tumor suppressor gene.
639
"Blimp1 is a tumor suppressor gene, whose inactivation may contribute to lymphomagenesis by blocking post-germinal center differentiation of B cells toward plasma cells."
8651
Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
5783
The PTPN13 protein has proapoptotic functions and can fuction as TSGs to suppress tumorigenesis.
9314
The work identifies KLF4 as a putative tumor suppressor in B-cell malignancies.
1029
Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: longitudinal study of Myc-induced lymphomagenesis.
51741
analysis in mice shows that WWOX has a tumor suppressor function
9411
PARG1 expression was substantially reduced & it displayed at least partial promoter methylation in all investigated mantle-cell lines & in 31 primary cases. PARG1 is a strong candidate tumor suppressor gene in MCL.
1026
P21(WAF1/CIP1) may be a tumor suppressor after all.
51741
Wwox hypomorphs had an increased incidence of B-cell lymphomas supports a role of Wwox as a tumor suppressor
8651
mediastinal B-cell lymphoma and hodgkin lymphoma cells share overlapping features and defective tumor suppressor gene SOCS-1 triggers an oncogenic pathway operative in both Hodgkin and non-Hodgkin lymphomas.
6776
Acts as a key tumor suppressor by reciprocally inhibiting expression of oncogenic nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) in T-cell anaplastic large cell lymphomas.
10395
"Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas."
100132074
FoxO factors mediate Myc-induced Arf expression and provide direct genetic evidence for their tumor-suppressive capacity.
3090
Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
7157
Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
8651
SOCS-1 mutations qualify as a tumor suppressor in mediastinal b-cell lymphoma.
8795
Thus TRAIL-R may function as an inflammation and tumor suppressor in multiple tissues in vivo.
1326
"Tpl2, a potent oncogene, functions as a tumor suppressor gene in chronically stimulated T cells."
90427
Bmf plays a critical role in apoptosis signaling and can function as a tumor suppressor.
639
PRDM1 may be a tumor suppressor in some primary central nervous system lymphoma and contribute to lymphomagenesis by impairing terminal differentiation
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