| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44000004 | HTLV-1 | ENSG00000168539.4 | protein_coding | CHRM1 | No | No | 1128 | P11229 Q53XZ3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM1 |
|---|---|
| DrugBank ID | DB00340 |
| Drug Name | Metixene |
| Target ID | BE0004890 |
| UniProt ID | P08912 |
| Regulation Type | antagonist |
| PubMed IDs | 12608172; 14315148; 5330346; 4866169 |
| Citations | Authors unspecified: Evaluation of an antispasmodic agent. Methixene hydrochloride (Trest). JAMA. 1966 Mar 7;195(10):851. doi: 10.1001/jama.1966.03100100103030.@@ABRUZZI W: THE USE OF METHIXENE HYDROCHLORIDE TO RELIEVE FUNCTIONAL GASTROINTESTINAL DISORDERS. J New Drugs. 1965 Mar-Apr;5(2):109-13. doi: 10.1002/j.1552-4604.1965.tb00233.x.@@Clarke S, Hay GA, Vas CJ: Therapeutic action of methixene hydrochloride on Parkinsonian tremor and a description of a new tremor-recording transducer. Br J Pharmacol Chemother. 1966 Feb;26(2):345-50. doi: 10.1111/j.1476-5381.1966.tb01913.x.@@Norris JW, Vas CJ: Mehixene hydrochloride and parkinsonian tremor. Acta Neurol Scand. 1967;43(4):535-8. doi: 10.1111/j.1600-0404.1967.tb05760.x. |
| Groups | Approved |
| Direct Classification | Thioxanthenes |
| SMILES | CN1CCCC(CC2C3=CC=CC=C3SC3=CC=CC=C23)C1 |
| Pathways | |
| PharmGKB | PA164783811 |
| ChEMBL | CHEMBL1201342 |
