| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44000004 | HTLV-1 | ENSG00000168539.4 | protein_coding | CHRM1 | No | No | 1128 | P11229 Q53XZ3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM1 |
|---|---|
| DrugBank ID | DB01085 |
| Drug Name | Pilocarpine |
| Target ID | BE0000092 |
| UniProt ID | P11229 |
| Regulation Type | agonist |
| PubMed IDs | 32310588; 28893976 |
| Citations | Panarese V, Moshirfar M: Pilocarpine. .@@Pronin AN, Wang Q, Slepak VZ: Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor. Mol Pharmacol. 2017 Nov;92(5):601-612. doi: 10.1124/mol.117.109678. Epub 2017 Sep 11. |
| Groups | Approved; Investigational |
| Direct Classification | Alkaloids and derivatives |
| SMILES | CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O |
| Pathways | |
| PharmGKB | PA450962 |
| ChEMBL | CHEMBL550 |
