| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44000004 | HTLV-1 | ENSG00000168539.4 | protein_coding | CHRM1 | No | No | 1128 | P11229 Q53XZ3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM1 |
|---|---|
| DrugBank ID | DB00979 |
| Drug Name | Cyclopentolate |
| Target ID | BE0000092 |
| UniProt ID | P11229 |
| Regulation Type | antagonist |
| PubMed IDs | 1848211; 17992517; 10025113; 19486927; 29085421 |
| Citations | Walkenbach RJ, Ye GS: Muscarinic cholinoceptor regulation of cyclic guanosine monophosphate in human corneal epithelium. Invest Ophthalmol Vis Sci. 1991 Mar;32(3):610-5.@@Solanki P, Cuprian-Beltechi AM, Cunnane TC: Cholinergic innervation of the guinea-pig isolated vas deferens. Naunyn Schmiedebergs Arch Pharmacol. 2007 Dec;376(4):265-74. doi: 10.1007/s00210-007-0198-y. Epub 2007 Nov 9.@@Tokoro T: [Developmental mechanism of low myopia and therapeutic possibilities. A review]. Nippon Ganka Gakkai Zasshi. 1998 Dec;102(12):796-812.@@Cuprian-Beltechi AM, Solanki P, Teramoto N, Cunnane TC: High spatial resolution studies of muscarinic neuroeffector junctions in mouse isolated vas deferens. Neuroscience. 2009 Sep 15;162(4):1366-76. doi: 10.1016/j.neuroscience.2009.05.064. Epub 2009 May 29.@@Kyei S, Nketsiah AA, Asiedu K, Awuah A, Owusu-Ansah A: Onset and duration of cycloplegic action of 1% cyclopentolate - 1% tropicamide combination. Afr Health Sci. 2017 Sep;17(3):923-932. doi: 10.4314/ahs.v17i3.36. |
| Groups | Approved |
| Direct Classification | Benzene and substituted derivatives |
| SMILES | CN(C)CCOC(=O)C(C1=CC=CC=C1)C1(O)CCCC1 |
| Pathways | |
| PharmGKB | PA164743019 |
| ChEMBL | CHEMBL1201338 |
